Name: 2-Methyl-3(5 Or 6)-(Methylthio) Pyrazine
Synonyms: Methylthio methylpyrazine
CAS Number: 28520-20-5
Recommended Use: Used in flavoring compounds, laboratory research
Manufacturer Contact: [Manufacturer’s Name, Address, Emergency Phone Number]
Formula: C6H8N2S
Molecular Weight: 140.20 g/mol
Product Codes: [Add as needed per supplier]
Restrictions on Use: Industrial use only, not for food, drug, or household application
Classification: Flammable liquid (Category 4), Skin irritant (Category 2), Eye irritant (Category 2A), Acute toxicity oral (Category 4)
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, harmful if inhaled or swallowed, may cause respiratory irritation
Pictograms: GHS07 (Exclamation mark), GHS02 (Flame)
Precautionary Statements: Avoid breathing vapors, wear gloves and eye protection, use only with adequate ventilation, wash thoroughly after handling
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Symptoms: Redness, itching, tearing, coughing, headache, nausea
Chemical Name: 2-Methyl-3(5 Or 6)-(Methylthio) Pyrazine
Concentration: 98% - 100%
CAS Number: 28520-20-5
Impurities: Minor traces of related pyrazine derivatives (specific levels may vary by batch; check certificate of analysis for limits)
Additives: None
Inhalation: Move person to fresh air, provide artificial respiration if not breathing, seek medical attention if symptoms persist, keep airway clear
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, get medical attention in case of irritation
Eye Contact: Rinse eyes with water for at least 15 minutes, keep eyelids open and apart, seek medical attention for continued irritation
Ingestion: Rinse mouth with water, do not induce vomiting unless instructed by medical personnel, never give anything by mouth to an unconscious person, get medical attention
Notes to Physician: Treat symptomatically, monitor for respiratory and neurological symptoms
Suitable Extinguishing Media: Foam, dry chemical powder, carbon dioxide, water spray (do not use water jet)
Unsuitable Extinguishing Media: Direct water stream may spread material
Specific Hazards: May emit hazardous fumes such as nitrogen oxides, sulfur oxides, carbon monoxide, carbon dioxide
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective clothing
Special Procedures: Cool exposed containers with water spray, avoid inhaling combustion products, move containers from fire area if safe
Personal Precautions: Evacuate area, ensure adequate ventilation, avoid breathing vapors, wear protective clothing including gloves and goggles
Environmental Precautions: Prevent run-off into drains, surface waters, and soil, inform authorities if seepage occurs outside containment
Methods for Clean-up: Absorb with inert material (sand, earth, vermiculite), collect in suitable waste container, decontaminate area with detergent solution, ventilate area, dispose of waste in accordance with local regulations
Spill Reporting: Notify appropriate agencies where necessary
Handling: Work in a well-ventilated area, avoid contact with skin, eyes, and clothing, keep containers tightly closed when not in use, do not eat, drink, or smoke while handling chemicals, wash hands thoroughly
Storage Conditions: Store in original container at cool (15-25°C), dry, well-ventilated location, away from direct sunlight, sources of ignition, and incompatible materials like strong oxidizers, acids
Incompatibilities: Avoid storing with oxidizing agents and acids
Handling Precautions: Use explosion-proof equipment and non-sparking tools, ground containers during transfer
Quantity Limits: Consult local regulations for maximum storage limits
Exposure Limits: No OSHA, ACGIH, NIOSH limits established; minimize exposure by best practices
Engineering Controls: Use local exhaust or general ventilation
Respiratory Protection: Organic vapor respirator if ventilation inadequate, approved by NIOSH
Eye Protection: Chemical safety goggles
Skin Protection: Chemical-resistant gloves (nitrile or neoprene), lab coat or apron
Hygiene Measures: Wash hands, forearms, and face after use, remove contaminated clothing
Environmental Controls: Routine checks for leaks, maintain equipment, prevent release to environment
Appearance: Pale yellow to light brown liquid or solid (depending on purity and temperature)
Odor: Characteristic, strong, sulfurous
Odor Threshold: Not established
pH: Not applicable (not water soluble)
Melting Point: 18–23°C
Boiling Point: 125–130°C at 15 mmHg
Flash Point: 100°C (closed cup, approximate)
Evaporation Rate: Not determined
Flammability: Capable of combustion
Explosion Limits: Not available
Vapor Pressure: Low (<0.1 mmHg at 25°C)
Vapor Density: >1 (air = 1)
Solubility: Insoluble in water, soluble in organic solvents
Partition Coefficient (log Kow): Not available
Auto-ignition Temperature: Not determined
Decomposition Temperature: Not established
Viscosity: Not established
Chemical Stability: Stable at normal temperatures and pressures
Conditions to Avoid: Heat, flames, sparks, incompatible materials
Reactivity: No dangerous reactions expected under normal conditions
Incompatible Materials: Oxidizing agents, strong acids, strong bases
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides, other unidentified toxic and/or irritating compounds
Polymerization: Will not occur
Likely Routes of Exposure: Skin contact, eye contact, inhalation, ingestion
Acute Toxicity: Harmful if swallowed or inhaled; LD50 (oral, rat) data unavailable for this exact compound, but structurally similar pyrazines show low to moderate toxicity
Skin Corrosion/Irritation: Causes irritation on prolonged or repeated contact
Eye Damage/Irritation: May cause redness and pain
Respiratory Sensitization: Possible upper airway tract irritation
Carcinogenicity: No classification or data available from OSHA, IARC, NTP
Mutagenicity: No data available
Reproductive Toxicity: No data available
Symptoms: Headache, nausea, dizziness, respiratory discomfort, possible allergic reactions in sensitized individuals
Ecotoxicity: No data available for aquatic or terrestrial toxicity; structurally similar compounds tend to be toxic to aquatic organisms at high concentrations
Persistence and Degradability: Likely low due to aromatic structure, breakdown through photochemical and microbial processes not established
Bioaccumulative Potential: Low to moderate; no data but expect slow accumulation in higher trophic levels
Mobility in Soil: Low, poorly soluble in water, high affinity for organic matter
Other Adverse Effects: Avoid entry to surface water, ground water, soil
Regulatory Reporting: Not classified as a marine pollutant under current transport regulations
Waste Disposal Methods: Incinerate at approved facility or dispose by chemical waste facility in accordance with local, regional, and national laws
Contaminated Packaging: Triple rinse, puncture, and dispose following hazardous waste regulation
Special Instructions: Do not discharge to environment, avoid landfill disposal where possible, handle residues and wash solutions as hazardous waste
Hazard Code: D001 if flammable; check local requirements for assignment
UN Number: Not assigned
Proper Shipping Name: Not regulated for transport under ADR, DOT, IATA, IMDG
Hazard Class: None assigned
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Special Precautions: Avoid transport with food and feedstuffs, secure containers, observe temperature limits if specified by supplier, inspect for leaks before shipping, label as per workplace requirements
Global Inventory Status: Check for registration in TSCA (USA), REACH (EU), DSL (Canada), AICS (Australia), ENCS (Japan), PICCS (Philippines), IECSC (China)
OSHA Hazard Communication: Classified as hazardous (irritant, flammable)
SARA Title III: Not listed on SARA 313 or Extremely Hazardous Substances
California Proposition 65: Not listed
WHMIS Classification: D2B (Toxic Material causing other toxic effects)
EU Classification: Xi (Irritant), R36/38 (Irritating to eyes and skin), S24/25 (Avoid contact with skin and eyes)
Label Elements: Required in all workplaces using or storing this compound, language as per GHS requirements
Other Regulations: Users must check local restrictions and ensure compliance with jurisdictional requirements
