MSDS for 2-Methyl-3(5Or6)-Ethoxy Pyrazine

Identification

Product Name: 2-Methyl-3(5Or6)-Ethoxy Pyrazine
Chemical Synonyms: Ethoxymethylpyrazine, Pyrazine, 2-methyl-5-ethoxy- or 2-methyl-6-ethoxy-
Chemical Formula: C7H10N2O
Molecular Weight: 138.17 g/mol
Manufacturer: Contact supplier/manufacturer for detailed information
Supplier Contact: Listed in purchase documents or manufacturer data
Recommended Use: Used in flavor and fragrance applications, research, and chemical synthesis
Restrictions: Avoid use outside recommended laboratory, industrial, or professional settings

Hazard Identification

Classification: Substance may cause eye, skin, and respiratory irritation; not classified as carcinogenic; data limited regarding chronic health effects
Label Elements: Pictogram for irritant, warning symbol
Signal Word: Warning
Hazard Statements: Causes mild skin and eye irritation; may cause respiratory discomfort if inhaled
Precautionary Statements: Avoid breathing vapors or dust; wash skin thoroughly after handling; wear protective gloves and eye protection
Emergency Overview: Slightly yellowish liquid with a strong, earthy, green odor; volatile; can be irritating upon contact or inhalation; no evidence of explosive or highly toxic properties, though safety measures should remain a priority

Composition / Information on Ingredients

Chemical Name: 2-Methyl-3(5Or6)-Ethoxy Pyrazine
CAS Number: 25686-42-4 (typical reference, confirm with supplier)
EC Number: Not specifically listed, derived from structural information
Content: ≥98% (purity depends on synthesis)
Impurities: Pyrazine derivatives, reaction byproducts —less than 2%
Other Components: No additives, stabilizers, or solvents declared for standard analytical samples

First Aid Measures

Eye Contact: Rinse immediately with plenty of clean water for at least 15 minutes; keep eyelids open and remove contact lenses if present; seek medical attention if pain or irritation continues
Skin Contact: Wash area with soap and plenty of water; remove contaminated clothing; in case of persistent redness or discomfort, consult physician
Inhalation: Move to fresh air at once; if symptoms like coughing or shortness of breath do not improve quickly, call for medical assessment
Ingestion: Do not attempt to induce vomiting; rinse mouth with water; if the person feels unwell or shows unusual symptoms, get medical support at hospital or poison center

Fire-Fighting Measures

Suitable Extinguishing Media: Small fires, use dry chemical powder, carbon dioxide, or alcohol-resistant foam; for larger scale fires, use water fog or spray
Unsuitable Media: Direct water stream may spread burning material
Special Hazards: Emits toxic fumes (such as nitrogen oxides and carbon monoxide) when heated or burned
Protective Equipment: Wear self-contained breathing apparatus, protective clothing, and gloves
Firefighting Instructions: Cool fire-exposed containers with water spray; avoid inhalation of fumes; evacuate area if flames threaten storage or containers

Accidental Release Measures

Personal Precautions: Avoid skin and eye contact; ventilate area; use gloves and goggles
Protective Equipment: Use chemical splash goggles, gloves made of nitrile, and lab coat
Emergency Procedures: Restrict access to spill area and notify responsible personnel; prevent release into environment
Spill Clean-Up: Absorb using inert material (such as sand or vermiculite); collect residue in a sealed chemical waste container; avoid generating dust or vapors
Environmental Precautions: Avoid discharge into drains, surface, or groundwater

Handling and Storage

Handling: Work in a well-ventilated space or fume hood; minimize all direct exposures by wearing gloves and eye protection; seal containers immediately after use
Storage: Store in tightly closed, labeled containers; keep away from light, moisture, and incompatible substances like strong oxidizers or acids; temperature control between 5–25°C is best
Incompatibilities: Strong oxidizing agents, acids, and bases can cause decomposition or hazardous reactions
Hygiene Practices: Wash hands thoroughly after handling; keep food, drink, and tobacco away from work area

Exposure Controls and Personal Protection

Exposure Limits: No established occupational limits for this compound; follow good industrial hygiene practices
Engineering Controls: Use local exhaust ventilation or fume hoods where vapor or dust may be generated
Respiratory Protection: Use certified respiratory protection if ventilation is inadequate or large amounts are being handled
Hand Protection: Nitrile or neoprene gloves recommended
Eye Protection: Safety goggles or glasses with side shields
Skin Protection: Suitable long-sleeve lab coat, chemical-resistant apron if significant exposure risk exists
General Safety: Practice regular hand washing and avoid direct contact with skin, eyes, and clothes

Physical and Chemical Properties

Appearance: Clear to pale yellow liquid
Odor: Intense, earthy, green, bell pepper-like
Odor Threshold: Detectable at extremely low concentrations (ppt)
pH: Not available
Melting Point: Below room temperature, estimated - based on structure
Boiling Point: 179–183°C (@ standard pressure)
Flash Point: Above 75°C (closed cup, estimated)
Evaporation Rate: Not measured, likely moderate
Flammability: Flammable liquid (category based on flash point)
Vapor Pressure: Low at room temperature
Solubility: Moderately soluble in water, highly soluble in alcohol and ether
Partition Coefficient (log Kow): 1.0–1.5 (estimated)
Vapor Density: Heavier than air (estimated based on similar pyrazines)
Decomposition Temperature: Above 200°C
Viscosity: Not measured
Density: ~1.06 g/cm³ (@ 20°C)

Stability and Reactivity

Chemical Stability: Remains stable under normal laboratory and storage conditions; avoid strong heat or light
Reactivity: No evidence of violent reactivity under recommended conditions
Hazardous Reactions: Contact with strong oxidizing agents may trigger fires or toxic fume release
Decomposition Products: Burning or decomposition produces nitrogen oxides, carbon monoxide, and carbon dioxide
Polymerization: Not known to occur
Other Incompatibilities: Strong acids or bases speed up decomposition, affecting purity of the material

Toxicological Information

Acute Toxicity: Low oral toxicity expected, but studies limited; estimated LD50 (oral, rat) >2,000 mg/kg
Skin Corrosion / Irritation: Occasional mild irritation if left on skin
Eye Damage / Irritation: Redness, watery eyes or mild pain possible if splashed
Respiratory Effects: Inhalation of vapor or aerosol can cause irritation of throat and nose, coughing; long-term inhalation data lacking
Allergenic Potential: Not a known skin sensitizer
Chronic Effects: No comprehensive studies available on long-term exposure or mutagenicity
Carcinogenicity: Not listed by IARC, NTP, OSHA, or EU as carcinogenic
Other Side Effects: High concentrations may cause headaches, dizziness, or nausea due to strong odor

Ecological Information

Ecotoxicity: Not well-studied; toxicity to aquatic life presumed low, but avoid contamination
Persistence: Expected to degrade slowly under aerobic conditions; likely not persistent over months/years
Bioaccumulation: Predicted low; structure suggests unlikely to accumulate in aquatic organisms
Mobility: Moderate in soil and water, based on solubility and log Kow
Aquatic Impact: Even small spills may impact sensitive organisms if concentrated in waterways
Other Environmental Effects: Prolonged presence in drainage or effluent could lead to odor complaints or affect microflora
Wastewater: Remove during standard wastewater treatment processes before discharge

Disposal Considerations

Product Disposal: Dispose of small quantities as hazardous laboratory waste; use high temperature incineration with afterburner and scrubber
Container Disposal: Triple-rinse and discard as hazardous chemical packaging if local regulations apply
Special Precautions: Do not pour down drain, into soil or regular trash; always separate from food and animal feed
Other Guidance: Consult state, local, or regional authorities about proper disposal procedures for chemicals and containers
Waste Codes: Assign according to local hazardous waste regulations and chemical classification

Transport Information

UN Number: Not yet assigned; consult updated databases
Proper Shipping Name: Organic liquid, n.o.s. (Not Otherwise Specified), if required
Transport Class: Handle as flammable liquid under DOT, IATA, IMDG classification unless evidence says otherwise
Packing Group: III, for low danger substances (estimate based on flammability)
Label: Flammable liquid pictogram
Environmental Hazards: Not regulated as a marine pollutant
Special Precautions: Always ship in tightly closed containers, away from oxidizers, and keep upright

Regulatory Information

US TSCA Status: Substance may require notification or exemption for manufacture/import; confirm with regulatory authority
EU REACH Status: Likely requires registration or notification if used above 1 tonne/year; check specific list
OSHA: Not yet assigned a PEL; general chemical safety regulations cover use
SARA Title III: Not listed as hazardous under Sections 302, 304, or 313
California Prop 65: Not listed
Other National Regulations: Check country-specific workplace, environmental, and chemical usage regulations
GHS Compliance: Labeling and safety data align with GHS recommendations for chemical irritants