Chemical Name: 2-Methoxy-3-Isopropyl Pyrazine
Synonyms: MIP, Pyrazine, 2-methoxy-3-(1-methylethyl)-, Flavoring compound
CAS Number: 25773-40-4
Recommended Use: Used in flavors and fragrances, research applications
Supplier Details: Manufacturer details usually printed on packaging, with address and emergency contact number.
Product Code: Varies by supplier, critical for identifying the substance during purchase or shipping.
Classification: Eye and skin irritant, Harmful if inhaled or ingested
Signal Word: Warning
Hazard Statements: May cause eye, skin, and respiratory irritation, Prolonged exposure could bring discomfort or headaches
Pictograms: Exclamation mark symbol for irritants
Precautionary Statements: Avoid breathing dust or vapor, Wear protective gloves and goggles, Wash thoroughly after handling; Seek medical attention if symptoms persist.
Substance: 2-Methoxy-3-Isopropyl Pyrazine
Formula: C8H12N2O
Concentration: Usually supplied neat or in diluted form for industry use, check actual label
Impurities: Information provided by supplier or batch-specific, important when used in sensitive environments
Chemical Family: Pyrazine derivatives, known for strong odor and flavor properties
Inhalation: Remove from exposure area to fresh air, Provide artificial respiration if not breathing, Seek medical attention for symptoms
Skin Contact: Remove contaminated clothing, Rinse skin thoroughly with soap and water, If irritation continues consult a doctor
Eye Contact: Flush eyes with water for at least 15 minutes, Remove contact lenses if present and safe, Consult an ophthalmologist if discomfort lingers
Ingestion: Rinse mouth with water, Don’t induce vomiting unless directed by a medical professional, Seek immediate medical advice for persistent symptoms
Suitable Extinguishing Media: Use carbon dioxide, dry chemical powder, foam; Water spray to cool exposed surfaces
Hazards from Combustion: May produce hazardous vapors, including nitrogen oxides, carbon monoxide, and carbon dioxide
Protective Equipment: Wear self-contained breathing apparatus and protective gear to avoid inhalation of fumes
Firefighting Instructions: Approach fire from upwind, Cool containers with water to prevent rupture, Evacuate area if flames spread
Personal Precautions: Evacuate unnecessary personnel, Ensure adequate ventilation, Wear gloves and eye protection
Environmental Precautions: Prevent runoff into drains and waterways, Contain spill with absorbent material
Cleanup Methods: Collect residue with inert absorbent (sand or earth), Shovel into secure container for disposal, Wash area with detergent and water after material is removed.
Reporting: Notify local authorities if spill enters public waterways or extensive contamination occurs
Handling: Use only in well-ventilated spaces, Avoid contact with skin and eyes, Do not breathe vapors, Wash hands before eating or drinking
Storage Conditions: Store in original tightly closed container, Keep away from heat sources, flames, and incompatible substances, Keep in a cool, dry, ventilated location
Incompatible Materials: Strong oxidizers, strong acids, alkali metals
Special Considerations: Label all containers with substance name and hazard identification to avoid confusion or accidental misuse
Engineering Controls: Use fume hoods or proper exhaust to keep airborne concentrations low, Eyewash stations and safety showers should be available
Personal Protective Equipment (PPE): Wear chemical splash goggles, resistant gloves (nitrile recommended), lab coat; In case of high vapor risk, use organic vapor respirator
Hygiene Measures: Do not eat, drink, or smoke near chemical, Wash hands and forearms after handling, Remove contaminated clothing immediately
Exposure Limits: Not established for this chemical, follow best laboratory safety practices
Appearance: Colorless to pale yellow liquid
Odor: Earthy, green bell pepper-like, very potent even at low concentrations
Melting Point: Not readily available, generally remains liquid at room temperature
Boiling Point: Around 210°C at atmospheric pressure
Solubility: Limited solubility in water, high solubility in organic solvents like ethanol or ether
Density: Approximately 0.98 g/cm³
Vapor Pressure: Low, but vapor may still be irritating due to strong odor
pH: Not relevant for neutral organic substances
Flash Point: Estimated above 85°C, handle away from open flames
Chemical Stability: Stable at ambient temperature and pressures when stored as recommended
Reactive Conditions: Heat, flames, strong oxidizers, acids, or alkalis can trigger hazardous reactions
Decomposition: Burning releases noxious gases, mainly nitrogen oxides and carbon oxides, irritating and potentially hazardous
Polymerization: Will not spontaneously polymerize under normal conditions
Potential Health Risks: Inhalation may bring headaches, dizziness, respiratory discomfort; Skin exposure causes irritation or redness; Eye contact burns or irritates; Ingestion brings nausea or abdominal distress
Acute Toxicity: Data specific to 2-methoxy-3-isopropyl pyrazine is limited; Similar pyrazines show low acute toxicity but strong odor effect at trace levels
Chronic Effects: No evidence of carcinogenicity; Prolonged exposure may lead to skin sensitization or respiratory irritation
Routes of Entry: Inhalation, dermal absorption, ingestion
Symptoms of Overexposure: Red or itchy skin, watery eyes, cough, headaches, nausea—especially after extended handling periods or large vapor releases
Aquatic Toxicity: Data limited, but pyrazines tend to be harmful to aquatic life at high concentrations
Persistence and Degradability: Not expected to persist long in environment, microbial action breaks it down; High odorant potency means even small leaks may have noticeable impact
Bioaccumulative Potential: Unlikely to bioaccumulate, based on available chemical analogs
Mobility: Moderate mobility in soil, quickly disperses if spilled on ground
Other Environmental Impact: Potent aroma may disrupt odor-based communication in wildlife near production or spill sites
Disposal Methods: Incinerate in a chemical incinerator equipped with afterburner and scrubber, When not available, send to licensed waste disposal center
Container Disposal: Empty containers should be rinsed with suitable solvent, then destroyed to prevent reuse
Waste Codes: Local or regional regulatory codes should be checked, usually treated as special chemical waste
Avoid: Do not pour into drains or allow to reach surface water or large soil areas
UN Number: Not assigned for this compound, but ships as a chemical not otherwise specified
Proper Shipping Name: Organic liquid NOS (with additional details according to carrier requirements)
Transport Classification: No special hazard class; Strong odor may require communication during shipping
Packing Group: III (if classified based on irritant nature)
Labeling: Clearly labeled with hazard pictograms and chemical name to alert handlers to risks
Shipping Conditions: Ship only in containers designed for tight sealing, avoid cargo areas exposed to heat
Global Inventory Status: Listed in TSCA (USA), EINECS/ELINCS (EU), AICS (Australia) or equivalents for major chemical inventories
Labeling Requirements: Conform to GHS labeling guidelines, including hazard pictograms and signal words
Workplace Regulations: OSHA workplace standard (USA) applies general chemical handling rules
Environmental Release: Must comply with limits for release to air, water, and soil under local and national laws
Food Additive Use: Subject to GRAS or equivalent review for use in flavors depending on jurisdiction, but always clarify intended use before purchase
