Material Safety Data Sheet for 2-Methoxy-3-Isobutyl Pyrazine

Identification

Chemical Name: 2-Methoxy-3-Isobutyl Pyrazine
Synonyms: MIBP; 2-Methoxy-3-(2-methylpropyl)pyrazine
CAS Number: 24683-00-9
Recommended Use: Flavor and fragrance manufacturing
Manufacturer: [Enter manufacturer details]
Emergency Contact: [Enter emergency contact details]

Hazard Identification

GHS Classification: Acute Toxicity (Oral) Category 4, Skin Sensitization Category 1
Signal Word: Warning
Hazard Statements: Harmful if swallowed, may cause allergic skin reaction, may cause respiratory irritation
Pictograms: Exclamation mark
Precautionary Statements: Wash skin thoroughly after handling, avoid breathing dust/vapor, use only outdoors or in well-ventilated area, wear protective gloves/clothes/eye protection, call poison center/doctor if feeling unwell.

Composition / Information on Ingredients

Substance: 2-Methoxy-3-Isobutyl Pyrazine
Chemical Formula: C9H14N2O
Concentration: 100% (for pure substance)
Impurities/Additives: None reported that affect classification

First Aid Measures

Inhalation: Move person into fresh air, keep comfortable for breathing, seek medical advice if symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin with water for at least 15 minutes, seek attention for irritation or reaction
Eye Contact: Rinse eyes with water, remove contact lenses if present and easy, continue rinsing, get help if irritation continues
Ingestion: Rinse mouth, do not induce vomiting unless directed by medical personnel, seek immediate medical attention if feeling unwell

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, foam
Unsuitable Extinguishing Media: High volume water jets
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, nitrogen oxides
Protective Equipment for Firefighters: Wear full protective gear, self-contained breathing apparatus
Fire Hazards: Vapor may form explosive mixture with air, keep containers cool with water spray

Accidental Release Measures

Personal Precautions: Use personal protective equipment, ventilate area, avoid dust formation or vapor inhalation
Environmental Precautions: Prevent entry into sewers/waterways, do not let product reach soil
Cleanup Methods: Absorb spill with inert material (sand, universal binder), shovel into container, wash spill site after material pickup

Handling and Storage

Handling: Handle in well-ventilated areas, avoid spills and contact with skin or eyes, keep away from ignition sources, no smoking
Storage Requirements: Store in tightly sealed containers, keep in a cool, dry place, protect from light, keep away from incompatible substances (strong acids/oxidizers)

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific limits established, minimize exposure
Engineering Controls: Use local exhaust ventilation, safety shower and eyewash recommended
Personal Protection: Protective gloves (nitrile or similar), chemical-resistant goggles, lab coat or apron, approved respirator if ventilation is insufficient

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Strong, earthy-green/vegetal scent
Boiling Point: Approx. 196°C
Melting Point: No available data
Vapor Pressure: Low at room temperature
Solubility: Slightly soluble in water, freely soluble in most organic solvents
Density: About 0.97 g/cm³ at 25°C
Flash Point: > 70°C (closed cup)
pH: Not applicable (non-aqueous)

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: No hazardous reactions expected under normal conditions
Incompatible Materials: Strong acids, strong oxidizers
Hazardous Decomposition Products: Combustion releases toxic fumes including carbon monoxide, nitrogen oxides
Conditions to Avoid: High heat, open flames, incompatible materials

Toxicological Information

Acute Toxicity: LD50 (oral, rat): Est. 200-600 mg/kg
Symptoms: Eye/skin irritation, respiratory discomfort, allergic reaction possible
Chronic Effects: No long-term studies, prolonged exposure may cause sensitization
Carcinogenicity: Not listed as carcinogen by IARC, OSHA, NTP
Other Data: No data on reproductive toxicity or mutagenicity

Ecological Information

Aquatic Toxicity: Toxic to aquatic life with long-lasting effects
Persistence and Degradability: Not rapidly biodegradable, may persist in the environment
Bioaccumulation Potential: Potential exists for bioaccumulation in aquatic organisms
Mobility in Soil: Low to moderate, due to low water solubility

Disposal Considerations

Waste Disposal: Dispose of in accordance with local, state, and federal regulations, do not pour down drains
Container Disposal: Rinse containers, dispose as hazardous waste
Special Precautions: Avoid release into environment, incinerate or send to chemical waste facility

Transport Information

UN Number: Not regulated for transport
Proper Shipping Name: Non-hazardous chemical
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Precautions: Use adequate packaging, keep containers tightly sealed to prevent accidental release, protect from physical damage and climatic extremes

Regulatory Information

Labeling: Label as hazardous if required by local law
Inventory Status: Listed on TSCA, REACH limits apply in the EU
Other Regulations: Satisfies OSHA Hazard Communication Standard; workplace exposure controls recommended
Restrictions: Avoid unregulated discharge, inform workers of hazards through training and labeling