Product Name: 2-Methoxy-3(5Or6)-Methoxy Pyrazine
Chemical Formula: C6H8N2O2
Synonyms: 2,3-Dimethoxypyrazine, Pyrazine, 2,5-dimethoxy- or 2,6-dimethoxy-
CAS Number: 1206-67-7
Intended Use: Used in flavor and fragrance industries, research and development
Manufacturer: [Insert supplier or laboratory information]
Contact Information: [Phone number, email, and address for emergencies or more details]
Emergency Telephone: [Insert 24/7 emergency number]
Hazard Classification: Eye irritant, mild respiratory irritant, low acute toxicity
Signal Word: Warning
Hazard Statements: Causes mild skin and eye irritation, may cause respiratory irritation if inhaled, could cause minor discomfort on ingestion
Pictograms: Exclamation mark (irritant)
Precautionary Statements: Avoid breathing dust or vapors, wear appropriate personal protective equipment, wash skin after handling, handle in well-ventilated spaces
Routes of Entry: Inhalation, skin contact, eye contact, ingestion
Potential Health Effects: Short-term exposure brings eye and skin irritation, prolonged exposure compounds irritation, inhaling dust may lead to coughing or sneezing
Chemical Identity: 2-Methoxy-3(5or6)-Methoxy Pyrazine
Common Name: Dimethoxypyrazine
Concentration: ≥98% (pure form)
Impurities: Trace aromatic hydrocarbons, pyrazine isomers
CAS Number: 1206-67-7
EC Number: [Insert EC number if available]
Other Components: Minor solvents or stabilizers as indicated by the supplier label
Inhalation: Move person to fresh air, support breathing if symptoms of coughing or dizziness appear, seek medical advice if discomfort persists
Skin Contact: Rinse exposed skin with plenty of water and mild soap, strip away contaminated clothing, monitor for rash or irritation
Eye Contact: Flush eyes with water for at least 15 minutes, holding eyelids open, remove contact lenses if present, consult a healthcare professional if eye redness continues
Ingestion: Rinse mouth with water, do not induce vomiting, give small sips of water if the person is conscious, obtain medical attention if unwell
Most Important Symptoms: Eye redness, skin dryness, mild throat irritation
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical powder, carbon dioxide
Unsuitable Extinguishing Media: High-pressure water streams
Specific Hazards: Combustion releases nitrogen oxides (NOx), carbon monoxide, carbon dioxide
Protective Equipment: Firefighters wear self-contained breathing apparatus and full chemical-resistant gear
Special Fire Procedures: Keep containers cool with water mist, prevent run-off from contaminating surface waters
Personal Precautions: Ventilate spill area, keep unnecessary personnel out, wear gloves, safety goggles, and dust mask
Environmental Precautions: Prevent chemical from entering drains, sewers, or open waterways, use dikes or absorbent material to contain
Cleanup Methods: Scoop up spilled material using non-sparking tools, place in a sealable container for disposal, wash spill site with water and detergent
Handling: Ensure good ventilation at workplaces, keep away from sources of ignition, avoid forming potentially dangerous dust clouds, wear eye and skin protection
Storage Conditions: Store in tightly sealed containers, keep container in a cool, dry, well-ventilated place, lock up and keep away from incompatible substances like acids or strong oxidizers
Storage Temperature: Keep below 25°C, protect from light and moisture
Engineering Controls: Use local exhaust systems, handle inside chemical hoods or well-ventilated rooms
Personal Protective Equipment: Safety goggles, Nitrile gloves, lab coats, dust mask or respirator (in dusty environments)
Hygiene Measures: Wash hands and forearms after use, take off protective clothing and wash before re-use, do not eat, drink, or smoke while working
Occupational Exposure Limits: Not established for this compound; observe general limits for nuisance dust (10 mg/m3 for inhalable particles)
Appearance: Pale yellow to light brown crystalline powder
Odor: Strong earthy, green, bell pepper-like aroma
Molecular Weight: 140.14 g/mol
Melting Point: 57 – 64°C
Boiling Point: Decomposes before boiling
Flash Point: Over 85°C (closed cup)
Vapor Pressure: Low at room temperature
Solubility: Slightly soluble in water, well soluble in ethanol, diethyl ether, and most organic solvents
Partition Coefficient (log Kow): Estimated 1 – 2
pH: Not applicable (neutral powder)
Density: Approximately 1.15 g/cm3
Chemical Stability: Stable in normal storage and use conditions, may decompose slowly on exposure to strong light or air
Incompatible Materials: Avoid contact with strong acids, oxidizing agents, and bases
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides during combustion
Conditions to Avoid: Heat, flame, prolonged exposure to moisture and air
Polymerization: No risk of hazardous polymerization occurs
Acute Toxicity: Limited animal data, expected to show low toxicity based on structural relatives
Irritation: Skin and eye irritant, likely to cause discomfort with repeated exposure
Sensitization: No data on skin or respiratory sensitization, chemically related pyrazines are rarely sensitizers
Long-term Effects: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity in related compounds, handle with care to avoid chronic inhalation
Other Health Effects: Inhaled dust causes throat and airway irritation; ingestion at small quantities unlikely to be strongly toxic but may upset stomach
Ecotoxicity: Data on aquatic or terrestrial toxicity not fully available; structurally similar pyrazines are not regarded as highly toxic to fish or insects
Persistence and Degradability: Not known to be persistent, expected to degrade slowly in the environment
Bioaccumulation: No established data; pyrazines typically have low potential for bioaccumulation
Mobility: Slight water solubility limits movement in soil, more mobile in organic-rich environments
Other Information: Handle accidental releases with care, limit environmental introduction as a precaution
Waste Treatment Methods: Collect waste material in sealed, labelled containers; hand off to licensed hazardous waste disposal operator
Disposal of Contaminated Packaging: Empty containers still pose a risk, triple rinse and recycle if acceptable or send for incineration at chemical waste facility
Special Precautions: Do not discharge waste to drains, waterways, or public sewers; comply with local, regional, and national waste disposal regulations
European Waste Code: Consult local regulations for classification (e.g., code for unused chemicals)
UN Number: Not assigned for this specific substance
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not classified as hazardous for transport
Packing Group: Not required
Special Precautions: Protect from physical damage, keep containers tightly closed during transport, check with carrier for packaging compatibility
Marine Pollutant: Not listed as a marine pollutant under IMDG
OSHA: Not specifically listed as a hazardous chemical under US regulations
SARA Title III: Not classified as an extremely hazardous substance
TSCA Inventory: Check if listed
REACH Registration: Evaluate need for REACH compliance if imported to EU
Other Regulations: Look for inclusion on national or state chemical inventories such as Canada (DSL/NDSL), Australia (AICS), Japan (ENCS), South Korea (KECI) prior to commercial use
Labeling: Ensure containers carry hazard pictogram, signal word, and hazard statements as defined
