Product Name: 2-Isocyanatoethyl Methacrylate
Chemical Formula: C7H7NO3
Synonyms: Methacrylic acid 2-isocyanatoethyl ester, IEM
CAS Number: 30674-80-7
Recommended Use: Resin modifier, polymerization agent
Supplier Details: Manufacturer information, emergency contact numbers, address, and telephone number specific to the exporting or distributing party
Emergency Telephone: Region-specific poison control contact, 24/7 emergency line for chemical spills or exposures
GHS Classification: Acute Toxicity (oral, dermal, inhalation), Skin Corrosion/Irritation, Serious Eye Damage, Sensitization (skin, respiratory)
Signal Word: Danger
Hazard Statements: Causes severe skin burns and eye damage, may cause allergic skin reaction, toxic by inhalation, suspected of causing genetic defects, harmful to aquatic life with long-lasting effects
Pictograms: Corrosive, health hazard, exclamation mark, environment
Precautionary Statements: Avoid inhalation of vapors or mists, wear protective gloves and eye protection, in case of inadequate ventilation wear respiratory protection, do not eat, drink, or smoke when handling
Other Hazards: Isocyanate vapors can cause rapid respiratory sensitization; repeated exposure may result in asthma-like symptoms
Chemical Name: 2-Isocyanatoethyl Methacrylate
CAS Number: 30674-80-7
Concentration: >98% by weight
Impurities: Traces of methacrylic acid, methanol, stabilizers to prevent polymerization, low-level residual isocyanate monomers
Stabilizing Additive: Typically contains an inhibitor against spontaneous polymerization (e.g., hydroquinone)
Other Components: No significant non-disclosed ingredients
Inhalation: Move exposed individual to fresh air immediately, keep at rest, seek immediate medical attention, provide oxygen if breathing is difficult, do not administer mouth-to-mouth rescue if exposure to vapors occurred
Skin Contact: Remove contaminated clothing, wash affected area with plenty of water and mild soap for at least 15 minutes, seek medical help for persistent irritation or blistering
Eye Contact: Rinse cautiously with water for at least 15 minutes while holding eyelids open, remove contact lenses if present and easy, obtain immediate medical attention regardless of symptom severity
Ingestion: Do not induce vomiting, rinse mouth well, seek emergency medical treatment immediately, never give anything by mouth to an unconscious person
Notes for Physicians: Treat symptomatically, monitor for delayed pulmonary edema after inhalation, consider possible development of sensitization and allergic reactions
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray for cooling containers exposed to fire but avoid direct water stream
Unsuitable Media: Do not use straight water jets, as risk of spreading or splashing exists
Special Hazards: Combustion releases toxic gases such as carbon monoxide, nitrogen oxides, hydrogen cyanide, and irritating isocyanate fumes
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear, including chemical-resistant suits
Firefighting Instructions: Evacuate area and fight fire from a safe distance, maintain upwind position, use water spray to cool unopened containers, prevent fire effluent from entering drains or open water
Personal Precautions: Evacuate unnecessary personnel, avoid all contact, ventilate area, wear appropriate chemical-resistant gloves, clothing, safety goggles, and respiratory protection
Environmental Precautions: Prevent further leakage by containing spill, do not discharge to drains, waterways, or soil, contact local authorities in case of large spills
Cleanup Methods: Absorb spillage with inert, non-combustible material (e.g., sand, earth, vermiculite), transfer to chemical waste container, decontaminate with dilute ammonia solution or sodium carbonate followed by large-scale water washing, dispose according to regulations
Decontamination: Ensure area is thoroughly washed after clean-up, ventilate area before allowing re-entering
Safe Handling: Wear protective clothing, gloves, eye protection, and face shield, thoroughly wash hands after handling, only handle in well-ventilated areas or under local exhaust systems, keep containers tightly closed when not in use, avoid breathing vapors, do not eat, drink, or smoke near product
Storage Conditions: Store in a cool, dry, and well-ventilated location, away from direct sunlight and sources of heat or ignition, keep separate from acids, bases, oxidizing agents, amines, water, and foodstuffs, use corrosion-resistant, tightly sealed containers, regularly check integrity of storage containers
Incompatible Materials: Avoid contact with strong acids, alkalis, amines, water, alcohols
Special Requirements: Store away from direct contact with air or moisture to prevent polymerization and hazardous decomposition
Occupational Exposure Limits: Specific government or local authority limits for isocyanates (e.g., ACGIH TLV for isocyanates, OSHA PEL)
Engineering Controls: Provide local exhaust ventilation in work areas, equip process enclosures and splash guards, use automated transfer mechanisms when possible
Personal Protective Equipment: Chemical-resistant gloves (nitrile, butyl rubber), goggles or face shield, long-sleeved lab coats or chemical aprons, respiratory protection (full-face air-purifying respirator with isocyanate cartridge or supplied air if exposure limits are exceeded)
Hygiene Measures: Wash hands and face thoroughly after handling, do not bring contaminated clothing home, dispose of protective gear safely, provide emergency eyewash and safety shower stations
Appearance: Clear to pale yellow liquid
Odor: Acrid, pungent
Odor Threshold: Not established, isocyanates can be detected at low concentrations
pH: Not applicable (non-aqueous)
Melting Point: Below room temperature, substance remains a liquid at ambient conditions
Boiling Point: 75-77°C (at reduced pressure)
Flash Point: 100°C (closed cup, varies with purity)
Evaporation Rate: Not established
Flammability: Combustible liquid
Explosion Limits: No data available; vapors may form explosive mixtures with air at high concentrations
Vapor Pressure: 0.1 mmHg at 25°C
Vapor Density: Heavier than air
Relative Density: About 1.07 g/cm³ at 20°C
Solubility: Insoluble in water, reacts with water, miscible with many organic solvents
Partition Coefficient (log Kow): Not determined
Auto-ignition Temperature: 230°C
Decomposition Temperature: Above 200°C, may emit toxic fumes
Viscosity: Low to moderate, depending on temperature
Chemical Stability: Stable under recommended storage conditions, but sensitive to moisture, elevated temperatures, direct light
Reactivity: Reacts with water, alcohols, amines, acids, and bases to form heat and hazardous products
Hazardous Reactions: Risk of rapid polymerization if in contact with moisture or incompatible substances, exothermic reactions possible
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, hydrogen cyanide, methacrylic acid, isocyanate vapors
Polymerization Risk: May occur if not properly inhibited, uncontrolled polymerization may cause hazardous pressure increase in closed containers
Acute Toxicity: Toxic if inhaled, skin contact, or ingested, can cause burns, lung edema, and medical complications
Inhalation: May cause respiratory tract irritation, coughing, shortness of breath, asthma-type symptoms, throat tickling, chest tightness
Skin: Severe irritation, burns, blistering, allergic sensitization possible after repeated/contact
Eyes: Severe irritation, irreversible damage, blindness possible
Chronic Effects: May sensitise through skin or respiratory exposure, repeated exposure linked to isocyanate asthma (chronic allergic respiratory disease), dermatitis
Carcinogenicity: Not officially classified as carcinogen by IARC or NTP; contains reactive isocyanate, which has high hazard for occupational asthma and allergy
Mutagenicity: Some evidence of genotoxicity in vitro, data are inconclusive
Other Data: Delayed effects possible, including occupational asthma and skin sensitization after repeated exposure
Ecotoxicity: Toxic to aquatic organisms, potential chronic effects on aquatic environments from low-level contamination
Persistence and Degradability: Hydrolyzes on contact with water to form insoluble, non-volatile polymers, may persist as solid residues in soil and sediment
Bioaccumulation Potential: Low, as isocyanate groups hydrolyze rapidly in environmental conditions and do not persist in animal tissue
Mobility in Soil: Low due to rapid reaction and polymerization, mobility limited by conversion to insoluble products
Other Adverse Effects: Localized pH changes possible in aquatic settings; runoff can affect water organisms due to high reactivity
Waste Disposal Methods: Incinerate according to local or national regulations, use specialized chemical waste management facilities, avoid discharge into drains or natural watercourses, do not bury containers
Contaminated Packaging: Empty containers retain residue, treat as hazardous, clean before disposal or send to approved drum recycling facilities
Special Precautions: Absorb spills with inert material and dispose with chemical waste, decontaminate packaging using dilute ammonia solution, do not reuse packaging for food or drink purposes
UN Number: 2929
Proper Shipping Name: Toxic liquid, corrosive, organic, n.o.s. (contains 2-Isocyanatoethyl Methacrylate)
Transport Hazard Class: 6.1 (toxic), 8 (corrosive)
Packing Group: I or II, depending on hazard assessment
Marine Pollutant: Yes, according to IMDG code
Special Transport Notes: Keep containers tightly closed, upright, and secured, segregate from incompatible goods (acids, alkalis, foodstuffs), emergency response required if leakage occurs in transit
Labeling: Toxic, corrosive, environmentally hazardous
Regulatory Reference: ADR/RID, IMDG, IATA/ICAO for international shipments
Regulatory Status: Subject to chemical control regulations in markets such as TSCA (USA), REACH (EU), DSL (Canada), and local workplace safety statutes
Label Requirements: GHS hazard pictograms and warning statements per CLP and OSHA Hazard Communication Standard
SARA Title III: Reportable under Section 313 as an isocyanate compound
WHMIS (Canada): Classified as D2A (very toxic material causing other toxic effects), E (corrosive material)
EU Classification: Harmful (Xn), Corrosive (C), Sensitizing (Xi), N (Dangerous for the environment)
Inventory Listings: Listed on most major chemical inventories, with restrictions on use and reporting requirements for employee exposure
Special Restrictions: Restricted access in workplace to trained personnel due to acute respiratory sensitization risk
