Chemical Name: 2-Ethylimidazole
Synonyms: 2-EtIm, 1H-Imidazole, 2-ethyl-
CAS Number: 1072-62-4
Molecular Formula: C5H8N2
Molecular Weight: 96.13 g/mol
Use: Intermediate in pharmaceuticals, epoxy resin curing agent, and chemical research applications.
GHS Classification: Acute Toxicity (Oral), Skin Corrosion/Irritation, Serious Eye Damage/Irritation, Specific Target Organ Toxicity
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin irritation, causes serious eye irritation
Precautionary Statements: Wear protective gloves, wash thoroughly after handling, avoid breathing dust or vapors, do not eat, drink or smoke during use
Pictograms: Exclamation Mark
Ingredient: 2-Ethylimidazole
Concentration: ≥99%
Impurities: Trace related imidazole compounds, trace water content
EINECS No: 213-646-0
REACH Registration: 01-2119979555-20-0004
Inhalation: Move person to fresh air, support breathing if necessary, seek immediate medical advice for symptoms.
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, consult medical attention if irritation persists.
Eye Contact: Rinse with plenty of water for at least 15 minutes, lift eyelids occasionally, seek prompt medical attention.
Ingestion: Rinse mouth, do not induce vomiting, provide water if victim is conscious, contact poison control or physician.
Suitable Extinguishing Media: Use water spray, dry chemical powder, carbon dioxide or foam.
Specific Hazards: Emits irritating or toxic fumes such as nitrogen oxides and carbon oxides when burned.
Protective Equipment: Firefighters use full protective suit and self-contained breathing apparatus to avoid inhaling decomposition products.
Special Precautions: Keep product containers cool using water spray to prevent explosion in heat or fire.
Personal Precautions: Wear suitable protective clothing, chemical resistant gloves, safety goggles or face shield; avoid contact with skin and eyes.
Environmental Precautions: Prevent spillage from entering drains or water systems, contain spill using inert absorbent material.
Clean-Up Methods: Sweep or scoop spilled material in a suitable container for disposal; ventilate area and wash spill site after material pickup is complete.
Handling: Work in a well-ventilated place, minimize dust generation, avoid inhaling fumes, avoid contact with skin and eyes, wash hands after handling.
Storage: Store in a cool, dry, well-ventilated area, keep away from incompatible substances such as oxidizers and strong acids, store in tightly closed containers, protect from direct sunlight.
Storage Class: Chemical Storage - General, not near food or drink
Special Considerations: Label storage container clearly, check for leaks regularly.
Occupational Exposure Limit: No specific limit established, use as low as reasonably achievable principle.
Engineering Controls: Use local exhaust ventilation, safety shower and eyewash station nearby.
Respiratory Protection: Use NIOSH-approved respirator for dust or mist if exposure limits risk of exceedance.
Skin Protection: Wear impervious gloves such as nitrile or neoprene.
Eye Protection: Chemical splash goggles or face shield.
General Hygiene: Remove contaminated clothing, wash hands before eating, avoid skin and eye contact.
Appearance: Off-white to yellowish crystalline solid
Odor: Slight amine-like smell
Melting Point: 47-49°C
Boiling Point: 267°C
Solubility: Soluble in water, ethanol, and other organic solvents
Density: 1.029 g/cm³ at 20°C
Vapor Pressure: Low
pH: Basic, around 9 (1% solution in water)
Flash Point: 122°C (closed cup)
Chemical Stability: Stable under normal storage and usage conditions.
Conditions to Avoid: Moisture, exposure to air, high temperature, sources of ignition.
Incompatible Materials: Strong oxidizing agents, acids, acid chlorides, acid anhydrides.
Hazardous Decomposition: Under fire, emits nitrogen oxides, carbon monoxide, carbon dioxide.
Polymerization: Does not occur under recommended conditions of use.
Acute Toxicity: Oral LD50 in rats approximately 619 mg/kg
Inhalation: May cause respiratory irritation.
Skin: Irritant to skin, prolonged/repeated exposure can cause redness, dryness.
Eyes: Causes eye irritation, redness, watering.
Sensitization: Not classified as a sensitizer.
Long-Term Effects: Prolonged exposure may affect liver, kidney function based on imidazole analog studies.
Carcinogenicity: No classification, no data on carcinogenic effects.
Mutagenicity: No indication in available data.
Reproductive Toxicity: No evidence recorded for this specific compound.
Aquatic Toxicity: Potentially harmful to aquatic life if released in significant quantities, LC50 for fish ~ 70 mg/L (96h, Oryzias latipes).
Degradation: Readily biodegradable under aerobic conditions, decomposes by microorganisms over time.
Bioaccumulation: Low bioaccumulation potential predicted.
Mobility: High solubility in water enhances mobility in the environment.
Other Effects: Avoid release to environment, monitor accidental release and contain immediately.
Disposal Methods: Dispose in accordance with local, regional and national regulations, incinerate or use licensed chemical disposal services.
Contaminated Packaging: Dispose of empty containers through municipal waste stream after cleaning, or send for professional recycling where appropriate.
Special Precautions: Avoid dispersal onto soil, into drains, or natural waterways.
UN Number: Not regulated for transport
Proper Shipping Name: 2-Ethylimidazole
Transport Hazard Class: Not classified
Packing Group: Not applicable
Environmental Hazards: Not classified as marine pollutant
Special Transport Precautions: Keep away from sources of ignition and strong oxidizers during transit, ensure proper labeling and secure packaging to prevent leaks.
TSCA Status: Listed on U.S. Toxic Substances Control Act inventory.
EU Classification: Xi – Irritant, R36/37/38 (Irritating to eyes, respiratory system, skin)
REACH Status: Registered with ECHA, compliant with European chemical safety guidelines.
Other National Inventories: Included on Canada DSL/NDSL, Australia AICS, Japan ENCS.
Label Elements: Pictograms, hazard statements, and safety instructions required on primary container or packaging.
Workplace Classification: Use in controlled environments, industrial exposure guidelines recommended by local authority.
