Product Name: 2-Ethyl-6-Methylpyrazine
Chemical Family: Pyrazines
CAS Number: 27043-05-6
Synonyms: 2-Ethyl-6-methyl-1,4-diazine
Recommended Uses: Flavor and fragrance ingredient, specialty chemical in laboratory research, possible industrial use in aroma chemistry
Supplier Details: Always found on the label or product information sheet shipped with the container; includes emergency contact phone number for quick access in case things go sideways
Classification: Flammable liquid, skin and eye irritant, may cause allergies in some people, hazardous if inhaled in large quantities, considered harmful if swallowed
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor, causes skin and eye irritation, may cause respiratory irritation, can provoke allergic skin reaction, toxic to aquatic life with long lasting effects
Precautionary Statements: Keep away from sparks or open flame, wear goggles and gloves, avoid breathing vapors, wash hands after handling, use only outdoors or in a well-ventilated area
Chemical: 2-Ethyl-6-Methylpyrazine
CAS No.: 27043-05-6
Purity: Minimum 98% pure
Impurities: Trace other pyrazines and potential solvents from manufacturing process
Formulation: Liquid (clear, pale yellow to colorless), single ingredient, no major additives unless otherwise noted on label
Inhalation: Move person outdoors into fresh air right away, loosen tight clothing, monitor breathing, seek medical attention if symptoms continue or worsen
Skin Contact: Wash skin with cool running water and mild soap for several minutes, remove contaminated clothing, get medical advice if irritation, swelling, or rash persists
Eye Contact: Rinse carefully with clean water for several minutes, blink often to help remove substance, do not rub the eye, seek medical care if irritation or blurred vision follows
Ingestion: Rinse mouth thoroughly, never try to make the person vomit, get prompt medical help, show container or SDS sheet to the healthcare provider if possible
Suitable Extinguishing Media: Use dry chemical powder, alcohol-resistant foam, or carbon dioxide for direct fires, water spray may help cool surrounding surfaces but cannot put out the flames directly
Special Hazards: Burning can produce noxious fumes like nitrogen oxides or carbon oxides, risk of flashback or re-ignition, vapors heavier than air may travel and reach flames
Protective Equipment for Firefighters: Full gear with self-contained breathing apparatus, avoid breathing fumes, keep upwind, do not let run-off reach drains or watercourses
Personal Precautions: Wear eye protection, gloves, work in a well-ventilated space, avoid breathing vapors
Environmental Precautions: Prevent spills from reaching drains, rivers, or soil
Cleanup Methods: Soak up with inert material (like sand or absorbent pads), shovel into tightly sealed containers, label for proper disposal as chemical waste, wipe contaminated areas with appropriate cleaning agents, ventilate area after cleanup, wash hands thoroughly afterward
Handling: Always keep containers closed when not in use, never use around ignition sources, avoid any unnecessary contact with skin or eyes, pour or transfer liquids inside a fume hood or under local exhaust, keep off clothing and shoes
Storage: Store cool and dry in a tightly sealed bottle, separate from strong oxidizers or acids, away from direct sunlight or temperature extremes, use secondary containment to reduce risk of leaks or spills, lock up if stored in shared spaces to minimize misuse
Engineering Controls: Local exhaust ventilation or lab fume hood, avoid using in enclosed, unventilated rooms
Personal Protection: Chemical resistant gloves (nitrile or neoprene), safety goggles or face shield, lab coat or protective clothing, if risk of splashing add face mask or splash apron
Respiratory Protection: Use respirator with organic vapor cartridges if exposure exceeds safe air levels or in case of accidental release
Work/Hygiene Practices: Wash hands and skin after working with this chemical, change out of contaminated clothing as soon as possible, do not eat or drink near the area of use
Appearance: Clear to pale yellow liquid, mild nutty or roasted aroma
Boiling Point: Around 178–181°C (352–358°F)
Melting Point: Below room temperature, specific data limited
Flash Point: Roughly 63°C (closed cup)
Vapor Pressure: Moderate at room temperature
Solubility: Slightly soluble in water, highly soluble in alcohols, ethers, and non-polar solvents
Density: Approx. 1.04 g/cm³
pH: Not applicable
Odor Threshold: Detectable at low concentrations (as it is a flavor compound)
Chemical Stability: Stable under normal lab and storage conditions
Reactivity: May react poorly with strong oxidizers, strong acids or reducing agents, incompatibility can cause heat and toxic fumes
Decomposition Products: Fumes of nitrogen oxides or carbon oxides if broken down by high heat or fire
Conditions to Avoid: Open flames, high heat, prolonged exposure to air (can degrade quality and increase risk of side reactions)
Likely Routes of Exposure: Inhalation, skin or eye contact, accidental ingestion
Acute Effects: May cause itchy skin, burning eyes, coughing or sore throat, stomach upset if swallowed
Chronic Effects: No long-term toxicity data available, not listed as a carcinogen under IARC, NTP or OSHA
Sensitization: Allergic reactions (like skin rash or sneezing) can occur in sensitive people
LD50: Oral toxicity in rats estimated above 1000 mg/kg, considered moderately toxic if swallowed
Other Health Hazards: Individuals with asthma or chemical sensitivities could react to vapors or prolonged exposure
Aquatic Toxicity: Harmful to aquatic life, can linger in waterways, keep out of storm drains, ponds, or rivers
Persistence and Degradability: Somewhat persistent, slow breakdown in soil or water, not easily biodegradable
Bioaccumulative Potential: Potential for buildup in aquatic organisms not fully documented
Mobility in Soil: Moderately mobile, especially if dissolved in rainwater or spilled on porous ground
Other Adverse Effects: Keep spills small, practice good containment and clean up to prevent problems downstream in nature
Waste Disposal Method: Collect in a tightly closed, leak-proof container, label as hazardous waste, transfer to a licensed chemical destruction or incineration facility
Contaminated Packaging: Clean empty container before disposal, follow local rules for chemical packaging, do not reuse for other materials
Special Precautions: Never pour down the drain, do not toss in regular trash, consult your organization’s waste management officer or local authority for best options
UN Number: UN 1993
Proper Shipping Name: Flammable Liquids, n.o.s. (contains 2-Ethyl-6-Methylpyrazine)
Hazard Class: 3 (Flammable Liquids)
Packing Group: III
Label: Flammable Liquid symbol
Transport Precautions: Keep sealed and upright, store containers securely in transit, avoid temperature extremes, notify carrier of any leaks or accidental releases
US Regulations: Not regulated as a hazardous air pollutant, not a controlled substance, included on the TSCA inventory, OSHA workplace hazard rules apply for labeling and safe work procedures
EU Regulations: Listed on EINECS, subject to CLP labeling (flammable and irritant), must be handled following REACH guidelines
Other Labelling: GHS message symbols—flame for flammable, exclamation for health risk
Further Requirements: Keep SDS available to all trained users, review safe handling each year, report significant spills to environment authorities as required in your region
