MSDS for 2-Ethyl-3-Methoxy Pyrazine

Identification

Chemical Name: 2-Ethyl-3-Methoxy Pyrazine
Synonyms: 2-Ethyl-3-Methoxypyrazine, Pyrazine, 2-ethyl-3-methoxy-
CAS Number: 25649-10-9
Recommended use: Industrial applications, chemical research, flavor or fragrance ingredient
Restrictions: Commercial use only, keep away from non-laboratory environments
Supplier Details: Manufacturer or distributer contact provided on request, safety officer contact available
Emergency Contact: National Poison Control center and company-specific emergency number

Hazard Identification

GHS classification: Flammable liquid, Harmful if swallowed, Eye and skin irritant
Signal Word: Warning
Pictograms: Flame, Exclamation mark
Hazard Statements: May cause respiratory irritation, Causes moderate eye irritation, Harmful if inhaled or ingested, Can ignite at room temperature in the presence of an ignition source
Precautionary Statements: Avoid breathing vapors or mist, Wash exposed skin thoroughly after handling, Wear protective gloves, Keep container tightly closed and away from flames, Store locked up
Health Hazards: Eyes watering or redness, possible drowsiness if inhaled, mild skin rash for sensitive individuals

Composition / Information on Ingredients

Chemical: 2-Ethyl-3-Methoxy Pyrazine
Concentration: ≥98% (w/w)
Impurities: Trace levels of related pyrazines below 2%
Molecular Formula: C7H10N2O
Molecular Weight: 138.17 g/mol

First Aid Measures

Inhalation: Move affected person to fresh air, keep at rest, seek medical attention if dizziness or breathing discomfort continues
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water, wash area with soap, seek medical advice for persistent irritation
Eye Contact: Flush with lukewarm water for at least 15 minutes, lift eyelids to ensure complete rinsing, seek medical care if pain or redness remains
Ingestion: Rinse mouth, do not induce vomiting, give small amount of water if conscious, contact poison center or physician promptly

Fire-Fighting Measures

Suitable Extinguishing Agents: Foam, dry chemical powder, carbon dioxide
Unsuitable Agents: Direct water jet, as it may disperse the substance
Special Hazards: Vapors form explosive mixtures with air, combustion produces toxic oxides of nitrogen and carbon
Protective Equipment: Firefighters should use full protective gear including self-contained breathing apparatus
Firefighting Instructions: Approach fire from upwind, cool unopened containers with water spray, avoid inhalation of fumes

Accidental Release Measures

Personal Precautions: Evacuate area, ventilate if safe, restrict access until clean-up completed, avoid inhaling vapors
Environmental Precautions: Prevent spills from reaching drains, soil, and waterways
Spill Clean-up Methods: Use inert absorbent (sand, earth), collect residue in sealable containers, clean area with water and detergent, dispose according to regulations

Handling and Storage

Handling: Use only in well-ventilated spaces, avoid contact with skin, eyes, and clothing, do not breathe vapors
Storage: Store in cool, dry, well-ventilated space, away from heat or ignition sources, tightly closed containers, keep incompatible substances away, label containers clearly

Exposure Controls and Personal Protection

Engineering Controls: Employ efficient ventilation, fume hood usage required for laboratory handling, local exhaust systems recommended
Personal Protective Equipment: Gloves made of nitrile, lab coat, chemical safety goggles, face shield if splash possible
Respiratory Protection: Use organic vapor respirator if exposure limits exceeded
Hygiene Measures: Wash hands thoroughly after use, remove contaminated clothing and wash before reuse, no eating or drinking in area of use

Physical and Chemical Properties

Appearance: Clear to pale yellow liquid
Odor: Strong, earthy, green bell pepper-like
pH: Not applicable (non-aqueous)
Melting Point: Less than -20°C
Boiling Point: 166–168°C at 760 mmHg
Flash Point: 60°C (closed cup)
Evaporation Rate: Moderate
Flammability: Flammable liquid
Vapor Pressure: 0.3 mmHg at 25°C
Solubility: Slightly soluble in water, soluble in organic solvents
Density: 1.04 g/cm³ at 20°C
Partition Coefficient (log Kow): 1.1–1.5
Auto-ignition Temperature: Above 200°C
Decomposition Temperature: Data not available
Viscosity: Not measured

Stability and Reactivity

Chemical Stability: Stable under ambient conditions in tightly sealed containers
Reactive Conditions: Exposed to open flame or elevated temperatures may decompose forming harmful gases
Incompatible Materials: Strong oxidizers, acids, bases, alkali metals
Hazardous Decomposition Products: Nitrogen oxides, carbon oxides
Polymerization: Not known to occur

Toxicological Information

Acute Toxicity: Oral LD50 (rat): estimated >200 mg/kg
Inhalation: May cause mild upper respiratory discomfort
Skin Irritation: Mild irritant to sensitive skin
Eye Contact: Causes irritation, redness, discomfort
Chronic Effects: Not expected to cause long-term effects in typical occupational use
Sensitization: No data, rare cases of allergic reaction possible
Carcinogenicity: Not listed by IARC, NTP, OSHA as carcinogen
Mutagenicity: Not mutagenic in laboratory tests
Reproductive Toxicity: No information found

Ecological Information

Environmental Toxicity: May be toxic to aquatic life at high concentrations
Persistence and Degradability: Moderately biodegradable in soil and water, breaks down under aerobic conditions
Bioaccumulation: Low potential based on log Kow
Mobility in Soil: Likely to move through soil slowly, binds to organic matter
Other Adverse Effects: No known major ozone depletion or global warming effects

Disposal Considerations

Methods: Dispose of in accordance with local, regional, and national environmental regulations
Unused Product: Hand over to authorized chemical waste disposal company
Contaminated Packaging: Rinse thoroughly, treat as hazardous waste
Incineration: Suitable for combustion in authorized facility
Other Notes: Do not release into surface water or drains, avoid landfill

Transport Information

UN Number: 1993
UN Proper Shipping Name: Flammable Liquid, N.O.S. (2-Ethyl-3-Methoxy Pyrazine)
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III (moderate hazard)
Marine Pollutant: Not classified
Special Precautions: Ensure secure packaging, keep containers upright, provide documentation with shipment
Transport Regulations: Subject to DOT, IMDG, IATA rules for flammable liquids

Regulatory Information

OSHA Status: Covered under hazardous chemical regulations
SARA 311/312: Fire hazard, immediate health hazard
TSCA Status: Listed
DSL/NDSL (Canada): Listed
EU Classification: Xn (Harmful), Xi (Irritant), R10 (Flammable)
Other Regulatory Notes: Check country-specific chemical inventory lists for updates, workplace exposure limits not established