Product Name: 2-Ethoxy Pyrazine
Chemical Family: Pyrazine Derivatives
CAS Number: 18138-04-0
Synonyms: Pyrazine, 2-ethoxy-
Recommended Use: Flavor and fragrance ingredient, chemical research
Supplier: Refer to manufacturer’s address on label
Emergency Contact: Local poison control center or regional emergency response number
Phone Number: Listed on supplier SDS label
Date Prepared: Refer to document footer for issue date
Classification: Acute toxicity (oral, inhalation), Eye irritation
Label Elements: Pictogram (exclamation mark), Signal Word: Warning
Hazard Statements: Harmful if swallowed, harmful if inhaled, causes eye irritation
Precautionary Statements: Avoid breathing vapors, wash hands thoroughly after handling, use eye protection
Routes of Exposure: Inhalation, ingestion, skin, eyes
Symptoms: Respiratory irritation, eye redness or pain, headache, nausea
Chemical Name: 2-Ethoxy Pyrazine
CAS Number: 18138-04-0
Concentration: 99% or higher
Impurities: Trace level (<1%) organic byproducts from synthesis
Hazardous Components: No classified hazardous additives present
Inhalation: Move to fresh air immediately, keep at rest, seek medical attention if symptoms persist
Ingestion: Rinse mouth with water, do not induce vomiting, obtain medical attention
Skin Contact: Wash with soap and water, remove contaminated clothing
Eye Contact: Rinse with water for several minutes, remove contact lenses if present, consult physician
Notes to Physician: Treat symptomatically, consider airway support for respiratory symptoms
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Specific Hazards from Fire: May emit nitrogen oxides, carbon oxides, toxic fumes
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective gear
Special Procedures: Cool exposed containers with water, avoid inhaling combustion gases
Combustion Products: Pyrazines break down to small organics and possible corrosive gases
Personal Precautions: Evacuate area, keep unnecessary personnel away, ventilate enclosed spaces
Environmental Precautions: Keep material out of drains, surface water, and soil
Spill Cleanup Methods: Absorb on inert material (sand, diatomaceous earth), place in chemical waste container, wash spill area with plenty of water
Protective Equipment: Chemical-resistant gloves, safety goggles, lab coat, respirator for dust or vapor
Handling: Handle with care, avoid breathing vapors, prevent contact with skin and eyes, use appropriate PPE
Storage Conditions: Store in cool, dry, well-ventilated area, keep container tightly closed, protect from sunlight, store away from incompatible materials such as acids, bases, and oxidizers
Hygiene Recommendations: Wash hands after handling, do not eat or drink in working area
Transfer Considerations: Use spark-resistant tools and proper grounding
Engineering Controls: Local exhaust ventilation, fume hood
Personal Protective Equipment: Chemical safety goggles, nitrile or neoprene gloves, protective clothing
Respiratory Protection: Approved respirator in case of insufficient ventilation
Control Parameters: No established occupational exposure limit, keep airborne levels low
Other Measures: Shower and eye-wash stations in area, avoid open flames or sources of ignition
Appearance: Clear colorless or pale yellow liquid
Odor: Strong earthy, green bell pepper aroma
Odor Threshold: Very low, detectable at parts-per-billion
Boiling Point: Approximately 150°C (302°F)
Melting Point: Not well documented, generally low
Flash Point: 56°C (133°F)
Autoignition Temperature: Not confirmed
Vapor Pressure: Low at room temperature
Solubility: Sparingly soluble in water, miscible with organic solvents
Density: 1.11 g/cm³ at 20°C
Partition Coefficient (Log Kow): Estimated between 1 and 2
Viscosity: Low
pH: Not applicable
Evaporation Rate: Not rapid at ambient conditions
Chemical Stability: Stable at standard temperature and pressure
Reactivity: No self-reactivity under normal use
Conditions to Avoid: High temperatures, open flames, strong oxidizing agents
Incompatible Materials: Strong acids, strong bases, oxidizers
Decomposition Products: Nitrogen oxides, carbon oxides, acidic gases on thermal breakdown
Hazardous Polymerization: Does not polymerize during storage or use
Acute Toxicity: LD50 oral (rat) approx. 200-400 mg/kg (moderate toxicity)
Skin Irritation: May cause mild to moderate irritation on contact
Eye Irritation: Causes irritation and redness
Inhalation: Exposure causes throat irritation, coughing, headaches at higher concentrations
Sensitization: No data suggesting strong allergenic response
Chronic Effects: No data on long-term toxicity; handle with standard laboratory caution
Mutagenicity/Carcinogenicity: Not listed as a known mutagen or carcinogen by IARC, NTP, or OSHA
Ecotoxicity: May be toxic to aquatic organisms at higher concentrations
Persistence and Degradability: Not rapidly biodegradable, stable under normal environmental conditions
Bioaccumulation Potential: Moderate due to partition coefficients
Mobility in Soil: Limited, absorbs onto soil particles
Other Effects: Report releases to proper authorities if product contaminates water bodies
Waste Management: Collect and contain material, do not flush to sewer
Methods of Disposal: Use high-temperature incineration, avoid landfill disposal; hand off only to licensed chemical disposal company
Contaminated Packaging: Triple rinse containers, consult local hazardous waste regulations
Special Precautions: Wear full PPE during disposal
UN Number: 2810
UN Proper Shipping Name: Toxic liquid, organic, n.o.s. (2-Ethoxy Pyrazine)
Transport Hazard Class: 6.1 (Toxic Substances)
Packing Group: III
DOT / IATA / IMDG: Regulated for ground, air, and sea transport
Special Transport Notes: Secure containers, ensure outer packaging prevents leaks, carry documentation
Environmental Hazards: Notify carrier if transported in bulk, prevent spillage during transit
OSHA Status: Not specifically listed, regulated under hazardous chemicals
TSCA Inventory: Listed or predicted based on similar derivatives
DSL/NDSL: Check Canadian regulations for any new substance requirements
SARA Title III: Does not appear on SARA 313 list
WHMIS Classification: Class D2B (toxic material causing other toxic effects)
EU Regulation: Classified as harmful (Xn), Risk Phrases 22/36/37, Safety Phrases S23/24/25/26
Other: Consult regional, state, and local regulations for unique restrictions or allowance
