MSDS for 2-Chloro-4-Nitro-1H-Imidazole

Identification

Product Name: 2-Chloro-4-Nitro-1H-Imidazole
Synonyms: 2-Chloro-4-nitroimidazole
Chemical Formula: C3H2ClN3O2
CAS Number: 1504-64-1
Recommended Use: Laboratory chemical, research and development
Restrictions on Use: Not for drug, food, or household use
Supplier Details: MSDS available from local chemical distributor or manufacturer, emergency phone contacts included
Emergency Telephone Number: Refer to local regulations and product supplier’s emergency response system

Hazard Identification

Classification: Acute toxicity (inhalation, oral), skin and eye irritation, suspected mutagenicity
Signal Word: Danger
Hazard Statements: Harmful if swallowed, causes skin irritation and serious eye damage, may cause respiratory irritation, suspected of causing genetic defects
Pictograms: Health hazard symbol, exclamation mark
Precautionary Statements: Avoid breathing dust or vapors, wash hands thoroughly after use, wear protective gloves and eye protection, handle only in well-ventilated area

Composition / Information on Ingredients

Chemical Identity: 2-Chloro-4-Nitro-1H-Imidazole
Concentration: 98-100%
Other Components: No significant impurities considered to influence classification

First Aid Measures

Inhalation: Move victim to fresh air, keep at rest, seek medical attention if symptoms occur such as coughing, dizziness, or breathing difficulty
Skin Contact: Remove contaminated clothing immediately, wash skin with plenty of water and soap, seek medical help if irritation persists
Eye Contact: Rinse continuously with water for several minutes, remove contact lenses if possible, continue rinsing, obtain medical attention at once
Ingestion: Rinse mouth with water, do not induce vomiting, get immediate medical advice
Most Important Symptoms/Effects: Burning sensation, irritation, redness, potential tissue damage depending on exposure route

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, foam, do not use water jet
Hazards from Combustion: Releases toxic fumes such as hydrogen chloride, nitrogen oxides
Special Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full chemical protective clothing
Firefighting Instructions: Evacuate area, keep containers cool with water spray, approach from upwind, avoid runoff to waterways
Explosion Hazard: Dust from finely divided material may form explosive mixtures in air under certain conditions

Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel, ventilate enclosed spaces, avoid breathing dust, wear recommended protective equipment
Environmental Precautions: Prevent product from entering drains, waterways, or soil, report spill to authorities under local regulations
Methods for Clean Up: Sweep up and collect spillage without generating dust, place in suitable container for disposal, decontaminate area with detergent solution, ventilate space thoroughly
Other Information: Handle waste as hazardous chemical, consult local environmental regulations

Handling and Storage

Safe Handling Recommendations: Use in chemical fume hood or well-ventilated area, avoid exposure to dust, avoid incompatible substances, never eat, drink, or smoke during use, maintain good industrial hygiene
Storage Conditions: Keep tightly closed in original container, store in cool, dry, well-ventilated place away from direct sunlight, segregate from oxidizers, acids, alkalis, and reducing agents, store at temperatures indicated by manufacturer
Specific End Use(s): Chemical manufacturing, research applications only

Exposure Controls and Personal Protection

Engineering Measures: Provide local exhaust ventilation, use closed handling systems for transfer, monitor airborne levels if possible
Occupational Exposure Limits: No formal threshold limit value established, minimize exposure based on precautionary principles
Personal Protective Equipment: Wear chemical-resistant gloves (nitrile or similar), lab coat, safety goggles or face shield, use respiratory protection if exposure risk exists, wash hands after handling, emergency eye wash and safety showers recommended in the work area
Environmental Controls: Prevent release into environment, use containment methods for handling powders

Physical and Chemical Properties

Appearance: Pale yellow to light brown crystalline solid or powder
Odor: Odorless or faint chemical odor
Odor Threshold: Not available
pH (solution): Not available
Melting Point/Freezing Point: 153-157°C
Boiling Point: Decomposes before boiling
Flash Point: Data not available
Evaporation Rate: Not available
Flammability: No flammability data, dust can be a fire hazard
Solubility: Slightly soluble in water, soluble in organic solvents such as DMF, DMSO
Vapor Pressure: Not applicable
Relative Density: Not specified
Partition Coefficient (n-octanol/water): Not determined
Auto-Ignition Temperature: Not established
Decomposition Temperature: Above 150°C
Viscosity: Not applicable for solids

Stability and Reactivity

Chemical Stability: Stable under recommended storage and use conditions, sensitive to strong light, heat, or acids
Reactivity: Reacts with strong oxidizing agents, incompatible with bases, acids, active metals
Conditions to Avoid: Strong heat, sparks, open flame, moist or humid environments
Incompatible Materials: Strong oxidizers, strong acids, reducing agents, alkali metals, moisture
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide and dioxide on decomposition
Polymerization: No hazardous polymerization expected

Toxicological Information

Acute Toxicity: Harmful by ingestion, potential for skin absorption, inhalation may cause serious respiratory tract irritation, animal data show moderate toxicity
Skin Corrosion/Irritation: Causes skin irritation or burns on prolonged or repeated exposure
Serious Eye Damage/Eye Irritation: Causes eye irritation, possible irreversible eye damage
Respiratory Sensitization: May cause allergy or asthma symptoms in susceptible individuals
Germ Cell Mutagenicity: Laboratory tests suggest potential mutagenic risk
Carcinogenicity: Not listed as carcinogen by IARC, NTP, or OSHA but health risks are possible given chemical class
Reproductive Toxicity: Not established
Target Organ Toxicity: Respiratory tract, eyes, skin
Symptoms of Exposure: Headache, nausea, irritation, possible long-term effects if not promptly treated

Ecological Information

Ecotoxicity: Harmful to aquatic life with long-lasting effects, avoid release to the environment, limited data suggest moderate acute toxicity for aquatic invertebrates
Persistence and Degradability: Not readily biodegradable, environmental persistence possible
Bioaccumulative Potential: Potential for bioaccumulation in aquatic organisms not ruled out
Mobility in Soil: Data insufficient but likely moderate due to low water solubility
Other Adverse Effects: May pose risk to soil micro-organisms; further data are needed for full environmental profile

Disposal Considerations

Waste Treatment Methods: Incinerate in a chemical incinerator equipped with afterburner and scrubber, follow all federal, state, and local regulations
Uncleaned Packaging: Dispose as unused product, triple rinse containers before disposal, contaminated packaging must follow same guidelines as product waste
Special Precautions for Disposal: Do not dispose of in household waste, do not allow product to reach sewage systems, keep material out of surface and ground water supplies

Transport Information

UN Number: Not assigned specific UN number for small laboratory quantities, for large shipments refer to regulatory body
Proper Shipping Name: Refer to best fit chemical shipping label, typically “Hazardous Chemical, n.o.s.”
Transport Hazard Class: Classified under relevant transport code for hazardous substances
Packing Group: III or as indicated for toxicity class
Environmental Hazards: Harmful to aquatic organisms, marine pollutant marking required for bulk shipment
Special Precautions for User: Handle with gloves, avoid spillage in transit, ensure sealed packaging, use additional containment if shipping by air or sea

Regulatory Information

Safety, Health, Environmental Regulations: Subject to regulations for harmful substances under workplace safety and environmental law
Label Elements: Compliant with GHS, CLP, OSHA Hazard Communication Standard
TSCA Status: Listed or exempted
REACH Registration: Provided by supplier, limited volume exemption for laboratory materials possible
SARA Title III: Not classified under specific SARA sections; check supplier documentation
Other Regulations: Requires chemical inventory tracking, safety training for handlers, environmental release must be reported under some local or international guidelines