Product Name: 2-Butyl Pyrazine
Synonyms: 2-sec-Butylpyrazine, Pyrazine, 2-(1-methylpropyl)-
CAS Number: 18138-04-0
Recommended Use: Flavoring agent, fragrance ingredient, chemical intermediate
Supplier Information: Company name, address, telephone, emergency phone number provided by supplier
Manufacturer: Listed on packaging or chemical supplier SDS
Email Address: Provided by supplier
Emergency Contact: Provided by chemical supplier or regional authority
Classification: Flammable liquid, Eye irritant, Skin irritant, Harmful if swallowed or inhaled
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation. Flammable. May cause discomfort through inhalation and ingestion. Can aggravate respiratory, skin, and eye conditions.
Pictograms: Flame, Exclamation mark
Precautionary Statements: Avoid breathing vapors and mist. Wear protective clothing, gloves, and eye protection. Keep away from sources of ignition. In case of inadequate ventilation, wear respiratory protection.
Other Hazards: Vapors may form explosive mixtures with air. Repeated exposure may cause skin dryness or cracking.
Chemical Name: 2-Butyl Pyrazine
Common Name: 2-sec-Butylpyrazine
CAS Number: 18138-04-0
Concentration: Purity typically ≥ 96%
Impurities: Trace related pyrazines or other organic solvents
Additives: No significant additives noted
Molecular Formula: C8H12N2
Molecular Weight: 136.2 g/mol
Inhalation: Move person to fresh air. Allow person to rest. If not breathing, provide artificial respiration. Seek immediate medical attention if breathing remains difficult.
Skin Contact: Remove contaminated clothing. Rinse skin with plenty of running water for at least 15 minutes. Call physician if irritation persists.
Eye Contact: Rinse with water for several minutes, lifting eyelids. Remove contact lenses if present and easy to do. Continue rinsing until chemical is gone. Seek medical attention for any lingering irritation.
Ingestion: Rinse mouth with water, do not induce vomiting. Keep person calm and seek medical attention. Never give anything by mouth to an unconscious person.
Acute Symptoms: May include headache, dizziness, nausea, irritation to eyes and throat. Large or prolonged exposures can increase severity.
Suitable Extinguishing Media: Foam, carbon dioxide, dry chemical powder, or water fog. Do not use water jets.
Unsuitable Extinguishing Media: Water stream may spread fire.
Fire Hazards: Vapors may travel to ignition source and flash back. Can produce irritating, corrosive, or toxic gases in fire.
Protective Equipment: Wear self-contained breathing apparatus and full protective gear. Avoid breathing vapors.
Special Procedures: Fight fire from a safe distance or protected location. Cool exposed containers with water spray.
Personal Precautions: Evacuate nonessential personnel. Avoid breathing vapors. Ventilate enclosed areas. Wear PPE such as gloves, goggles, protective clothing.
Environmental Precautions: Prevent entry into sewers, drains, and waterways. Notify authorities if significant environmental contamination is possible.
Containment Measures: Stop source if safe. Dike area with absorbent material such as sand or vermiculite.
Clean-up Methods: Soak up with inert absorbent, place in chemical waste container. Clean affected area with water and detergent. Dispose of in accordance with regulations.
Decontamination: Wash contaminated surfaces thoroughly after clean-up is complete.
Handling: Use only with local exhaust or general ventilation. Avoid contact with skin, eyes, and clothing. Do not inhale vapor or mist. Take steps to prevent static buildup. No eating, drinking, or smoking in work area.
Storage: Store in cool, dry, well-ventilated place. Keep container tightly closed. Store away from heat, sparks, flame, and incompatible chemicals such as strong oxidizers. Keep out of direct sunlight.
Incompatible Materials: Avoid strong oxidizing agents, acids, and alkalis.
Specific End Use(s): Observe good hygiene and safety practices specific to the chemical process or final product.
Engineering Controls: Use adequate local exhaust ventilation and process enclosures. Use safety showers and eye wash stations where exposure is possible.
Exposure Limits: No specific occupational exposure limits set; minimize exposure as with any organic solvent.
Personal Protective Equipment (PPE): Chemical-resistant gloves (nitrile or neoprene), splash-proof safety goggles, coveralls or lab coat, closed footwear.
Respiratory Protection: Use organic vapor respirator if ventilation is not sufficient or if exposure limits may be exceeded.
Hygiene Measures: Wash hands thoroughly after handling. Remove contaminated clothing and wash before reuse.
Environmental Controls: Prevent release into environment by using closed systems and spill containment.
Appearance: Clear to pale yellow liquid
Odor: Powerful roasted, nutty, earthy aroma
Odor Threshold: Detectable at low ppm levels
pH: Not applicable (not aqueous)
Melting Point/Freezing Point: Data not widely available; slight lowering below room temperature
Boiling Point: Approximately 193°C (379°F)
Flash Point: Around 65°C (closed cup)
Evaporation Rate: Data unavailable, typically slow
Flammability: Flammable liquid
Upper/Lower Flammability Limits: Not established
Vapor Pressure: Low at 20°C
Vapor Density: Heavier than air
Specific Gravity (Density): 0.980 (approximate)
Solubility: Insoluble in water, soluble in alcohols, ethers, and oils
Partition Coefficient n-octanol/water (log Kow): Not determined
Autoignition Temperature: Not established
Decomposition Temperature: Not specifically determined
Viscosity: Liquid, low viscosity
Chemical Stability: Stable under normal conditions of use and storage.
Thermal Decomposition: Decomposes at high temperature to form toxic fumes.
Reactivity: Reacts with strong oxidizers, may generate hazardous products.
Hazardous Reactions: Exothermic reactions possible with incompatible materials.
Conditions to Avoid: Flames, hot surfaces, sparks, incompatible chemicals.
Hazardous Decomposition Products: Oxides of nitrogen, carbon monoxide, carbon dioxide, and other noxious gases.
Polymerization: Not known to occur under normal conditions.
Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Effects: Eye and skin irritation. Inhalation can cause nose and throat discomfort, headaches, nausea. Swallowing may result in gastrointestinal distress and systemic effects.
Chronic Effects: Prolonged or repeated skin contact may cause dermatitis or sensitization. Repeated exposure may affect central nervous system.
Acute Toxicity (LD50): Not fully established; expected to have moderate toxicity by analogy with similar pyrazines.
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, ACGIH, or OSHA.
Mutagenicity/Reproductive: Not enough data concerning mutagenic or reproductive hazard potential.
Symptoms of Overexposure: Irritation, dizziness, headaches, fatigue, nausea.
Ecotoxicity: No specific data for aquatic or terrestrial species, treat as harmful to aquatic organisms based on structure and usage.
Persistence and Degradability: Expected to degrade over time in environment, but slow hydrolysis and volatilization could occur.
Bioaccumulative Potential: Unlikely to bioaccumulate significantly but may persist in certain media.
Mobility in Soil: Can migrate if released, particularly if spilled on loose soil. Insoluble in water limits leaching.
Other Adverse Effects: No known effects on ozone layer or other global environmental parameters.
Waste Methods: Dispose as hazardous waste under federal and local regulations. Collect in suitable containers for recovery or disposal.
Container Handling: Empty containers should be rinsed and disposed of safely. Avoid puncturing or incinerating closed containers.
Disposal of Product: Consult local waste authority or chemical waste contractor. Use licensed disposal facilities for organic chemicals.
Regulations: Follow local, regional, and national regulations related to hazardous chemical disposal.
Contaminated Packaging: Triple rinse before disposal; treat as hazardous material.
UN Number: Not regulated for small quantities; check shipping status for large shipments.
Proper Shipping Name: Not classified as dangerous goods for transport in most countries.
Transport Hazard Class: Flammable liquid (if above threshold amounts).
Packing Group: III (minor hazard); depends on regulation.
Marine Pollutant: Not specifically identified as marine pollutant.
Special Transport Precautions: Avoid heat and ignition sources during transport; protect from damage.
Inventory Status: Listed on TSCA (USA), DSL (Canada), EINECS/ELINCS (Europe), AICS (Australia), ENCS (Japan), and KECI (Korea).
Regulatory Classification: Not specifically regulated; general chemical safety laws apply.
Workplace Hazard: Subject to OSHA hazard communication standard (USA), WHMIS (Canada), and similar global regulations.
Restricted Use: Not intended for food, drug, or household use without appropriate clearance.
International Chemical Safety: Labels and SDS should match GHS recommendations. Observe all applicable requirements for transport, storage, and disposal.
