Product Name: 2-Butyl-3-Methyl Pyrazine
Chemical Family: Pyrazines, Alkyl-substituted
CAS Number: 5521-55-1
Other Names: 2-n-Butyl-3-methylpyrazine
Recommended Uses: Food flavoring, fragrance compound, laboratory reagent
Manufacturer: Contact details provided on package
Emergency Contact: Use local poison control center or chemical emergency hotline, details provided by your supplier
Formula: C9H14N2
Molecular Weight: 150.22 g/mol
Main Hazards: Combustible chemical, skin irritant, can result in eye discomfort, vapor may irritate respiratory passages, low oral toxicity in small exposures, flammable vapors possible if heated
Classification: Eye irritant (Category 2A), Skin irritant (Category 2), Flammable liquid (Category 4)
Labeling Elements: Flame icon, Exclamation mark
Signal Word: Warning
Hazard Statements: May cause skin and eye irritation, vapors may make breathing unpleasant, product can catch fire above 60°C
Precautionary Phrases: Avoid all contact with skin and eyes, keep away from heat sources or open flames, use ventilation to control vapors, wear gloves and protective eyewear in lab or production workplace
Chemical Identity: 2-Butyl-3-Methyl Pyrazine
Purity: Greater than 98% for most laboratory uses, trace impurities may vary depending on supplier
Impurities: Minor pyrazine structural isomers and aliphatic hydrocarbons possible at below 2% combined
Appearance: Pale yellow to colorless liquid, strong roasted/earthy odor
Solubility: Not easily dissolved in water, easier in organic solvents like ethanol or ethyl acetate
Eye Contact: Rinse eyes with plenty of clean water for at least fifteen minutes, remove contact lenses if present, seek prompt medical help if irritation stays
Skin Contact: Rinse skin well with running water and mild soap, take off contaminated clothes immediately, seek care if rash shows up
Inhalation: Get fresh air right away, keep affected person calm and warm, if feeling unwell or breathless, get medical help
Ingestion: Rinse mouth with water, avoid vomiting unless medical people say otherwise, ask for medical attention if large amounts are swallowed
Hospital Treatment: Show product container or label to healthcare workers if available
Extinguishing Media: Carbon dioxide, dry chemical, foam, use water spray to cool surfaces exposed to fire
Hazardous Combustion: During a fire, toxic fumes of nitrogen oxides, carbon monoxide, and carbon dioxide may be released
Special Equipment: Use self-contained breathing gear, wear full protective suit, evacuate area if fumes are strong
Firefighting Tips: Avoid breathing combustion gases, keep drums cool with water spray
Personal Protection: Wear gloves, chemical goggles, protective clothing, make sure there's plenty of air flow
Spill Response: Stop leak at source if safe, soak up with inert material like sand or earth, collect spill for safe disposal, wipe residues with damp cloth
Environmental Caution: Keep out of sewers, surface water, and soil; build barriers with absorbent material if needed
Cleanup: Dispose of collected waste using legal hazardous waste systems, wash contaminated surfaces with plenty of water
Handling: Use only in well-ventilated areas, handle away from open flames, static electricity, and hot surfaces, avoid splashing or vapor exposure, keep personal hygiene, wash thoroughly after work
Storage: Store in tightly sealed containers, place in cool, dry, and well-ventilated rooms, segregate from oxidizers or strong acids and bases, keep away from direct sunlight, keep original packaging intact until use
Recommended Containers: Use glass, specific high-density polyethylene, or other resistant synthetic materials
Engineering Controls: Run chemical processes with local exhaust ventilation or under fume hood, keep air flow directed away from worker faces
Personal Protection: Wear impervious gloves (nitrile or neoprene), tight-fitting safety goggles, lab coat or apron, closed footwear
Respiratory Protection: Use an approved respirator if vapor levels go above workplace exposure guideline limits
Exposure Limits: No set OSHA, ACGIH, or EU limits, but best practice is to keep air levels below irritation threshold
Work Practice: Avoid eating, drinking, or smoking in handling zones, keep work surfaces clean
Physical State: Oily liquid
Color: Pale yellow to almost colorless
Odor: Characteristic roasted, earthy, nutty smell
Melting Point: Below room temperature, rough estimate 4-8°C
Boiling Point: 185–187°C
Flash Point: Around 65°C (closed cup test)
Auto-ignition Temperature: Not well established, likely above 200°C
Vapor Pressure: Low, less than 1 mm Hg at 25°C
Solubility: Practically insoluble in water, soluble in organic solvents
Relative Density: 0.96–0.98
Partition Coefficient: log Kow estimated around 2.5–3
Chemical Stability: Stable under normal storage and handling conditions
Reactivity: Can react with strong oxidizing agents, exposure to strong acids or bases may change stability
Hazardous Reactions: Avoid heating over flash point, rapid vaporization or chemical breakdown possible if fire breaks out
Decomposition Products: Burns to make toxic nitrogen oxides, carbon dioxide, and carbon monoxide
Routes of Exposure: Main exposures are by skin contact, eye splash, or inhaling vapors
Potential Effects: May irritate skin or eyes, vapors can bother nose or throat, large doses swallowed by animals cause drowsiness
Acute Toxicity: Oral LD50 (rat): >2000 mg/kg, skin and vapor LD50 not well researched
Sensitization: No strong evidence for allergic reaction in regular users
Chronic Effects: Not enough study to say if long-term exposure risks exist, best to minimize repeated exposure
Carcinogenicity: Not listed as known or suspected human carcinogen by IARC, OSHA, or NTP
Aquatic Toxicity: Not acutely toxic at low concentrations, but can cause harm to fish or aquatic insects if large spills reach streams
Degradability: Likely to break down slowly in natural conditions, more quickly under sunlight or in well-aerated soils
Bioaccumulation: Log Kow near 3 suggests some potential to build up in aquatic life scales, treat as a chemical with moderate persistence
Mobility: Sticks to soil and sediments, not highly mobile in ground water
Other Environmental Effects: No evidence of ozone depletion or greenhouse properties, but direct dumping into nature is unsafe
Waste Handling: Collect leftovers, contaminated gloves, and wipes as hazardous chemical waste
Disposal Method: Send sealed waste containers to licensed chemical incinerator or hazardous waste contractor
Regulatory Tips: Never pour chemical or solutions containing 2-Butyl-3-Methyl Pyrazine into drains, rivers, or trash
Reuse: Recover or recycle in industrial-level operations if purity allows, do not reuse in food or flavor without verification
UN Number: Not listed under standard UN numbers, ships under “not regulated” class for most routes within US and EU
Shipping Name: 2-Butyl-3-Methyl Pyrazine, flavor compound
Transport Hazard Class: Not regulated as dangerous under ADR/RID, IMDG, IATA in most volumes
Packing Group: III (if regulated), use strong leakproof containers, discourage glass for export shipments
Special Precautions: Label outer packages with chemical name and emergency contact, ship away from strong oxidizers and acids
Inventory Status: Found in TSCA (US), EINECS (Europe), listed in Australia AICS, Japan ENCS
Workplace Limits: Not formally listed in OSHA PELs or ACGIH TLVs, follow general organic vapor guidance
Food and Flavor Status: FEMA GRAS flavor, use within government and industrial guidelines only
Other Regulations: Check local rules for chemical flavors or workplace safety, some countries set additional handling or export controls
