Chemical Name: 2-Bromothiophene
Other Names: 2-Thienyl bromide
CAS Number: 1003-09-4
Manufacturer Information: Contact details printed on supplier documentation
Recommended Use: Pharmaceutical research, synthesis of organic intermediates, laboratory chemical
Emergency Phone: Refer to supplier emergency hotline for region-specific contact
Hazard Classification: Flammable liquid and vapor, skin and eye irritant, harmful if inhaled
Signal Word: Warning
Hazard Statements: Causes skin irritation, may cause respiratory tract irritation, flammable liquid and vapor exposure risks
Pictograms: Flame, exclamation mark symbol
Precautionary Statements: Avoid breathing vapors, use explosion-proof equipment, keep away from open flames, use only in well-ventilated areas, wash exposed skin thoroughly after handling
Chemical Identity: 2-Bromothiophene
CAS Number: 1003-09-4
Concentration: Greater than 98%
Impurities: Trace organic compounds, brominated byproducts under quality control limits
Other Ingredients: None reported or present in significant amounts
Inhalation: Remove to fresh air, keep breathing clear, seek medical attention if discomfort persists
Skin Contact: Wash with soap and plenty of water; remove clothing and shoes if soaked, contact medical care for signs of persistent irritation
Eye Contact: Rinse immediately with plenty of running water, lift eyelids to ensure thorough rinsing, get checked by physician if problems remain
Ingestion: Do not induce vomiting, rinse mouth if person is conscious, take to emergency room for further evaluation, show label if possible
General Advice: Provide symptom-driven support, monitor vital signs, deliver oxygen if breathing is labored
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical powder, CO₂, do not use direct water stream on burning chemical
Specific Hazards: Combustion releases toxic fumes including bromine, sulfur oxides, potential for rapid vapor spread
Protective Equipment: Self-contained breathing apparatus, full protective fire gear, prevent skin and eye contact
Advice for Firefighters: Cool containers with plenty of water if safe, evacuate area if fire escalates, approach fire from upwind direction, prevent runoff from contaminating drainage
Personal Precautions: Use protective gloves, eye/face shields, chemical-resistant clothing, ensure adequate ventilation
Spill Containment: Stop leak if safe to do so, absorb with vermiculite or sand, prevent chemical from entering waterways or sewers
Clean-up Procedures: Place residue in closed, labeled container for disposal; ventilate area well; decontaminate tools and equipment afterward
Environmental Precautions: Notify authorities if spill leads to environmental release, follow local guidelines for hazardous chemical spills, consider risk to groundwater or wildlife
Handling: Wear suitable protective gear, work in a fume hood, keep containers closed when not in use, ground all transfer containers
Storage: Store in cool, dry, and well-ventilated area, separate from heat sources or open flames, keep tightly sealed in glass or chemical-resistant containers, label clearly
Conditions to Avoid: High heat, direct sunlight, incompatible chemicals such as oxidizers
Incompatible Materials: Strong acids, bases, oxidizing agents, alkali metals, sources of ignition
Occupational Exposure Limits: No established OSHA or ACGIH limits for this compound, good industrial hygiene practices advised
Engineering Controls: Use chemical fume hood, ensure eye-wash and safety shower nearby, employ proper laboratory ventilation
Personal Protection: Chemical splash goggles, butyl rubber gloves, flame-resistant lab coat, avoid contacts with eyes, skin, clothing
Respiratory Protection: Use NIOSH-certified respirator for organic vapors if exposure limits exceeded or in case of inadequate ventilation
Hygiene Measures: Wash hands before eating or drinking, launder contaminated clothing, handle chemical containers with care to prevent leaks or spills
Appearance: Colorless to pale yellow liquid
Odor: Slightly pungent, characteristic
Odor Threshold: Low; not precisely determined
pH: Not applicable
Melting Point: -16°C
Boiling Point: 154–157°C
Flash Point: 51°C (closed cup)
Evaporation Rate: Not determined
Flammability: Flammable liquid
Vapor Pressure: 4 mmHg at 25°C
Vapor Density: Heavier than air
Solubility: Insoluble in water; miscible with common organic solvents
Partition Coefficient: log Kow ~2.5
Auto-ignition Temperature: Not established
Decomposition Temperature: Not established
Viscosity: Not determined
Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: Can react with strong oxidizers, bases, some metals
Hazardous Reactions: No dangerous polymerization under normal conditions; hazardous gases may form with incompatible substances
Decomposition Products: Toxic fumes of bromine, sulfur oxides, carbon oxides released on burning or decomposition
Conditions to Avoid: Heat, sparks, open flames, contact with strong oxidizers
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Effects: Causes skin and eye irritation, can produce respiratory tract discomfort, ingestion harmful
Chronic Effects: Data limited, no long-term human studies available
Toxicity Data: Oral LD₅₀ (rat) estimated at 800 mg/kg; vapors may produce headache, nausea, respiratory irritation
Sensitization: Not known to cause allergic reactions
Carcinogenicity: Not classified as a human carcinogen by major agencies
Mutagenicity/Reproductive Toxicity: No available data for long-term effects in animal studies
Aquatic Toxicity: Harmful to aquatic organisms, potential for bioaccumulation
Persistence & Degradability: Slowly biodegradable in the environment
Mobility in Soil: Low mobility due to limited water solubility
Environmental Fate: Tends to partition into sediments, limited breakdown in surface water
Ecotoxicology Notes: Avoid uncontrolled release to soil or waterways, observe strict containment during handling and disposal
Disposal Methods: Use approved hazardous waste incineration facility, follow local environmental agency guidelines, do not pour into drains or sewers
Container Disposal: Triple rinse and puncture before offering as chemical waste, avoid reuse of chemical containers
Precautions: Seal all waste in labeled containers, document all waste movements
Special Instructions: Comply with all legal regulations regarding hazardous waste, include MSDS with waste shipments as required
UN Number: UN 3271
Proper Shipping Name: Brominated aromatic compound, liquid
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Marine Pollutant: Yes
Special Transport Precautions: Label packages clearly, secure tightly, avoid stowing with food or incompatible items
Transport Labels: Flammable liquid, marine pollutant
Regulatory Notes: Follow IATA, IMDG, DOT guidelines for hazardous chemical transport
TSCA (US): Listed
REACH (EU): Pre-registered or registered substance
Hazard Symbols: GHS02 (flammable), GHS07 (irritant)
Risk Phrases: R10 (flammable), R36/37/38 (irritant to eyes, respiratory tract, skin)
Safety Phrases: S16 (keep away from sources of ignition), S26 (if in eyes, rinse immediately), S36/37 (wear suitable protective clothing/gloves)
Other Regulations: Subject to workplace exposure controls, hazardous labeling requirements, and hazardous waste disposal rules
Note: Always consult local, state, and federal regulations regarding purchase, handling, storage, and disposal of hazardous chemicals like 2-bromothiophene
