Product Name: 2-Aminothiazole Hydrochloride
Chemical Formula: C3H5ClN2S
CAS Number: 2480-64-6
Synonyms: 2-Aminothiazolium chloride, Thiazol-2-amine hydrochloride
Recommended Use: Intermediate for organic synthesis, laboratory reagent
Company Identification: Supplier address, emergency contact number, and responsible department information provided at purchase
Emergency Telephone: Listed on the bottle label for 24-hour access
Classification: Acute toxicity (oral), irritant for skin and eyes
GHS Label Elements: Pictograms with exclamation marks
Signal word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, may cause respiratory tract irritation
Precautionary Statements: Avoid breathing dust, wash exposed skin after handling, use protective gear, avoid untreated release into environment
Routes of Exposure: Inhalation, ingestion, eye and skin contact
Chemical Name: 2-Aminothiazole Hydrochloride
Concentration: 98–100% (pure material)
CAS Number: 2480-64-6
Impurities: Trace organic or inorganic impurities below regulatory thresholds
Inhalation: Move person to fresh air, seek medical attention if symptoms like cough or sore throat persist
Skin contact: Remove contaminated clothing, rinse affected area with soap and water for 15 minutes, consult a doctor if irritation continues
Eye contact: Flush eyes gently with plenty of water for at least 15 minutes, remove contact lenses, seek medical help if discomfort or redness stays
Ingestion: Rinse mouth, drink water if alert, do not induce vomiting, medical attention required for symptoms like nausea, abdominal pain
Flammability: Not classed as flammable but can decompose under fire conditions to release toxic gases (nitrogen oxides, sulfur oxides, hydrogen chloride)
Suitable Extinguishing Media: Use water spray, dry chemical, carbon dioxide, foam for surrounding fire; do not use direct water jet
Special Protection for Firefighters: Firefighters need full protective gear and self-contained breathing apparatus
Other Precautions: Avoid inhaling combustion products, control runoff to prevent environmental release
Spill Response: Ventilate area, evacuate unnecessary personnel, avoid dust generation
Personal Precautions: Put on gloves, goggles, lab coat or overall, avoid contact with skin and eyes
Cleanup Procedures: Scoop up carefully to avoid dust, place in approved container, use damp cloth for residues, dispose of waste as hazardous chemical
Environmental Protection: Prevent further leakage or spillage, keep out of waterways, drains, soil
Safe Handling: Use in well-ventilated areas or fume hoods, avoid inhaling dust and direct contact, avoid eating or drinking in workplace, wash hands after handling
Storage Requirements: Keep in tightly closed original container, store away from incompatible materials like strong acids or oxidizers, place in a cool, dry, well-ventilated spot
Special Considerations: Label containers clearly, prevent physical damage, inspect regularly for leaks or degradation
Engineering Controls: Local exhaust ventilation, use of glove box or fume hood in research labs
Occupational Exposure Limits: No established national exposure limits, minimize dust exposure as precautionary principle
Personal Protective Equipment: Protective gloves, safety goggles, lab coat, dust mask (N95 or similar) if airborne powder present
Hygiene Measures: Wash hands and face before breaks and after work, decontaminate protective equipment and surfaces
Appearance: Pale yellow to beige crystalline powder
Odor: Faintly sulfuric, not pronounced
Melting Point: 220–230°C (with decomposition)
Boiling Point: Not applicable (decomposes)
Solubility: Soluble in water, sparingly soluble in ethanol
pH (1% in water): About 4.5–5.5
Vapor Pressure: Not available, negligible at room conditions
Relative Density: Around 1.4–1.6 (approximate)
Molecular Weight: 140.61 g/mol
Chemical Stability: Stable for storage under recommended conditions, decomposes if heated strongly or exposed to moisture over prolonged periods
Reactivity: Reacts with strong oxidizers, acids, may release toxic gases
Hazardous Decomposition Products: Hydrogen chloride, sulfur oxides, nitrogen oxides
Conditions to Avoid: Prolonged exposure to light and moisture, excessive heat
Incompatible Materials: Strong acids, strong oxidizers
Acute Toxicity: Harmful if swallowed, estimated LD50 (oral, rat) between 200–500 mg/kg
Skin/Eye Irritation: Irritates skin and mucous membranes, causes eye redness, possible corneal damage if not rinsed out
Inhalation: Can irritate respiratory tract, sneezing, coughing may occur
Sensitization: No clear evidence of skin sensitization in available reports
Chronic Toxicity: No long-term human data, repeated exposure can cause cumulative skin and mucous irritation
Aquatic Toxicity: Harmful to aquatic organisms, possible long-term adverse effects on water systems
Persistence/Degradability: Limited data; likely to degrade slowly in environment, increased risk if released in significant quantities
Bioaccumulation: No indication of significant bioaccumulation, but best practices avoid any direct environmental release
Mobility in Soil: Moderately mobile in moist conditions
Other Adverse Effects: Not expected to disturb ecosystems if handled responsibly
Disposal Methods: Dispose as hazardous laboratory chemical in accordance with national, regional, and local regulations
Packaging: Use original, labeled containers or approved chemical waste bins
Residues: Flush minor residues with large volumes of water if permitted; otherwise, absorb in inert material and treat as hazardous
Special Instructions: Never discard in municipal waste or untreated drains
UN Number: Not listed under major transport regulations
Transport Hazard Class: Not classified as dangerous for transportation
Proper Shipping Name: 2-Aminothiazole Hydrochloride
Packing Group: Not assigned
Label Requirements: Package securely, prevent any leakage during shipment, document for chemical content
Other Requirements: Include safety paperwork and SDS copy in original language and English
TSCA (US): Listed in inventory
REACH (EU): Pre-registered or exempted as chemical intermediate or research sample
Australian AICS: On list
WHMIS (Canada): Controlled product, class D2B (toxic material causing other toxic effects)
Labelling: Must have risk and safety phrases in accordance with local workplace regulations
Other Regulations: Hazardous according to OSHA Hazard Communication Standard; safety reporting required for significant users
