Product Name: 2-Amino-3,5-Dibromopyrazine
Chemical Formula: C4H3Br2N3
Synonyms: 3,5-Dibromo-2-Pyrazinamine
CAS Number: 39586-91-5
Use: Laboratory chemical, pharmaceutical intermediate, research
Manufacturer Contact: Provided on purchase documentation
Emergency Phone: Refer to local poison control authority or manufacturer’s emergency line
GHS Classification: Acute Toxicity (Oral, Dermal, Inhalation, Eye Irritation, Skin Irritation)
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, toxic to aquatic life
Precautionary Statements: Wear chemical-resistant gloves, protective eyewear, face mask when handling; avoid release into environment
Pictograms: Exclamation mark, Environment
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Potential Health Effects: Burns, headaches, nausea, coughing, digestive tract irritation
Chemical Identity: 2-Amino-3,5-Dibromopyrazine
CAS Number: 39586-91-5
Purity: Typically >98%
Impurities: Trace related brominated and aminated pyrazines possible
Additives: None indicated across major suppliers
Inhalation: Immediately move individual into fresh air, keep at rest, support breathing with oxygen if available, seek medical attention
Skin Contact: Remove contaminated clothing, wash exposed skin thoroughly with soap and water, do not reuse clothing unless cleaned, medical advice if irritation persists
Eye Contact: Flush eyes with running water for fifteen minutes, hold eyelids apart, seek medical attention if discomfort continues
Ingestion: Rinse mouth, do not induce vomiting unless directed by professional, consult medical service promptly
Most Important Symptoms: Redness, itching, burning sensation, nausea, shortness of breath, dizziness
Suitable Extinguishing Media: Dry chemical, CO2, foam, water spray
Unsuitable Media: Avoid high-pressure water jets
Hazardous Combustion Products: Releases bromine fumes, nitrogen oxides, carbon oxides
Protective Equipment: Self-contained breathing apparatus, full protective suit
Fire-Fighting Advice: Evacuate area, keep containers cool with water spray, fight fire from safe distance
Personal Precautions: Wear chemical gloves, tight safety goggles, and dust mask to prevent inhalation and bodily exposure, ventilate area
Environmental Precautions: Prevent further leakage or spillage if safe to do so, do not release to drains or natural water sources
Containment: Sweep up to prevent dispersal, avoid airborne dust generation, collect into chemical waste containers
Cleaning Methods: Damp cloth or moist absorbent for small spills, dispose with hazardous waste, clean affected surfaces with water after collection
Handling: Handle only in well-ventilated chemical fume hood, avoid skin and eye contact, do not breathe dust
Storage Conditions: Keep in tightly closed original container, store in cool, dry space out of direct sunlight, segregate from strong oxidizers and alkali materials
Incompatible Materials: Oxidizing agents, strong bases
Safe Packaging: Use airtight glass or plastic containers, label clearly, keep away from food items
Engineering Controls: Fume hood, eye wash station, safety shower should always be available
Personal Protection: Chemical-resistant gloves (nitrile, neoprene), lab coat, closed-toe shoes, splash-proof goggles, NIOSH-approved dust respirator
Hygiene Measures: Wash hands thoroughly after handling, remove contaminated clothing before entering other workspaces or public areas
Exposure Limits: No specific OSHA, ACGIH, or NIOSH limits established; minimize exposure as a prudent practice
Appearance: Pale yellow to tan crystalline solid or powder
Odor: Faint chemical aroma
Molecular Weight: 251.90 g/mol
Melting Point: 192-196°C
Boiling Point: Not readily available (decomposes)
Solubility: Poor in water, soluble in organic solvents such as DMSO and DMF
Density: Approx. 2.2 g/cm3
pH: Not relevant
Flash Point: Not available
Partition coefficient: Not tested
Chemical Stability: Stable under standard laboratory temperatures and atmospheric pressure
Reactivity: Reacts with strong oxidizers and bases
Hazardous Reactions: Contact with acids, bases, or oxidizers can trigger hazardous decomposition
Decomposition Products: Bromine compounds, nitrogen oxides
Conditions to Avoid: Moisture, high heats, incompatible material storage
Acute Toxicity: Harmful if inhaled, absorbed through skin, or ingested (exact LD50 not established, related compounds show moderate toxicity)
Skin Corrosion/Irritation: Causes noticeable irritation on contact
Eye Damage/Irritation: May trigger severe stinging, possible inflammation
Respiratory Sensitization: Dust inhalation can lead to coughing, throat discomfort, headache
Chronic Effects: Prolonged exposure can aggravate skin, lungs, or digestive tract
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No data available; limited studies on structural relatives; handle with care
Ecotoxicity: Toxic to aquatic organisms, can cause long-term environmental damage
Persistence and Degradability: Data not available; pyrazine derivatives show slow breakdown in environment
Bioaccumulation Potential: Lacks specific data; brominated compounds noted for persistence
Mobility in Soil: Expected low mobility due to low water solubility
Other Adverse Effects: Prevent release into soil, ditches, sewers, or waterways
Waste Disposal: Dispose according to official chemical waste regulations in clearly labeled hazardous waste containers
Contaminated Packaging: Rinse containers with suitable solvent/water prior to discarding, treat as hazardous waste
Methods of Disposal: Incinerate in certified facility or send for professional hazardous waste treatment
Disposal Precautions: Protect handlers with gloves and goggles during disposal operations
UN Number: Not assigned specifically for this chemical
UN Proper Shipping Name: Chemical, N.O.S. (not otherwise specified)
Transport Hazard Class: Not classified under major dangerous goods lists in small lab quantities
Packing Group: Not allocated
Special Precautions: Clearly label all containers, use robust, sealed packaging, avoid rough handling or stacking during shipment
OSHA Status: No specific status, treat as hazardous chemical
TSCA Inventory: Check supplier’s compliance with Toxic Substances Control Act
SARA Title III: Not listed as reportable, but toxic chemical management recommended
REACH Registration: Consult local and European regulations for registration needs
Other National/International Regulation: Safety data sheets comply with GHS, review additional requirements for special handling or disposal
Safety, Health, Environmental Regulations or Legislation Specific: Maintain recordkeeping of quantities and usage, undergo regular risk review as per local guidelines
