Product Name: 2-Acetylthiophene
Chemical Name: 1-(Thiophen-2-yl)ethanone
CAS Number: 88-15-3
Synonyms: Thiophene-2-yl methyl ketone, Ethanone, 1-(2-thienyl)-
Intended Use: Intermediate for pharmaceuticals or chemicals
Manufacturer/Supplier: Commonly available from specialty chemical suppliers
Emergency Contact Number: Provided by supplier on product label
GHS Classification: Flammable liquid, Category 3; Acute Toxicity (Oral), Category 4; Skin and eye irritant
Hazard Statements: May cause skin and eye irritation, harmful if swallowed, fire risk if exposed to ignition sources
Pictograms: Exclamation mark, flame symbol
Precautionary Statements: Wash hands after handling, only use in well-ventilated areas, wear eye and skin protection, keep away from sparks or flames, avoid eating or drinking during use
Potential Health Effects: Can irritate mucous membranes, inhaling vapors might cause nausea or headaches, skin exposure sometimes leads to redness or rash, ingestion can upset the stomach
Chemical Name: 2-Acetylthiophene
Chemical Formula: C6H6OS
Concentration: 98–100%
Impurities: Trace levels of thiophene or acetic acid
Other Additives: None declared
Inhalation: Move injured person to fresh air without delay, provide warm blankets if shivering starts, seek medical attention for breathing difficulty
Skin Contact: Remove contaminated clothing, rinse affected area generously with water, wash gently with soap, see a healthcare provider if redness lingers
Eye Contact: Flush eyes with running water, keep eyelids open, remove contact lenses soon, continue rinsing for 15 minutes, call a medical expert if irritation sets in
Ingestion: Do not force vomiting, rinse mouth with water, get medical help quickly, let doctor decide if further measures needed
Notes for Emergency Crew: Watch for respiratory symptoms, bring chemical details to hospital
Suitable Extinguishers: Dry chemical powder, foam, carbon dioxide, do not use water streams
Special Hazards: Vapors may travel with air currents, can ignite far from leak, heat may break down compound into toxic fumes including carbon oxides, sulfur oxides
Protective Equipment: Wear full-face respirators, flame-resistant suits, gloves, boots
Firefighting Advice: Stay upwind, keep containers cooled with water if exposed to flames, avoid contaminating runoff water with extinguishing material
Personal Protection: Put on chemical splash goggles, gloves, wear suitable clothing and shoe covers
Environmental Protection: Block access to drains, use sand or earth to contain liquid
Clean-Up: Absorb spill with inert material, place in an appropriate waste container, wipe affected area with damp rags using ventilated conditions, avoid sparks, ventilate space thoroughly after cleaning
Disposal: Follow local hazardous waste disposal rules
Handling: Work in ventilated space, avoid breathing vapors, keep away from heat and open flames, store only in containers bright-marked for flammable chemicals, do not eat or smoke near work area
Storage: Place in cool, dry, well-sealed containers, shield from sunlight, keep away from acids and strong oxidizers, store at room temperature, keep bottle shut tight after each use
Control Parameters: No OSHA PEL or ACGIH TLV currently available for this compound
Engineering Controls: Use fume hoods or local exhaust ventilation, laboratory work should involve splash guards
Personal Protection: Wear nitrile gloves, lab coats or aprons, chemical splash goggles, in closed rooms use organic vapor respirators
Hygiene: Wash hands carefully after work, shower after extended exposure, keep work clothes separate from personal garments
Appearance: Pale yellow to amber liquid
Odor: Strong, sweet, pungent
Molecular Weight: 126.18 g/mol
Boiling Point: About 208°C
Melting Point: -13°C
Flash Point: 88°C (closed cup)
Solubility: Moderately soluble in water, highly soluble in organic solvents
Vapor Pressure: 0.66 mmHg at 25°C
Density: About 1.13 g/cm³ at 20°C
Evaporation Rate: Not rapid under ambient conditions
Chemical Stability: Stable if kept cool and dry
Reactivity: Reacts with strong oxidizers, acids can accelerate breakdown
Hazardous Decomposition: Exposes sulfur compounds and carbon monoxide, possible acrid smoke on heating
Polymerization: No risk under normal conditions
Incompatible Materials: Avoid keeping near peroxides, nitric acid, chlorinating agents
Likely Routes of Exposure: Inhalation, skin and eye contact, accidental ingestion
Acute Effects: Nausea, throat irritation, mild headaches on vapor inhalation, skin contact might bring itching, swallowing can cause abdominal pain
Chronic Effects: Prolonged exposure lacks detailed studies but may dry out skin, lead to recurring headaches
LD50 (Oral, Rat): Approximately 1,000 mg/kg
Carcinogenicity: No studies linking to cancer, not evaluated by IARC or NTP
Sensitization: No noted allergies in typical use, though skin reactions possible in sensitive people
Ecotoxicity: Substance is moderately toxic to aquatic organisms, especially fish and invertebrates
Persistence: Breaks down in air and water over days, not persistent in soil
Bioaccumulation: Risk is low in normal environmental concentrations
Mobility: Moves through water and soils, vapors do not linger in air long
Precautions: Avoid spilling into streams, sewers, or streets
Disposal Methods: Gather waste in labeled, sealed containers for chemical disposal services
Do Not: Pour down sewer or throw in trash
Incineration: Acceptable method if carried out by licensed provider with emission controls
Local Regulations: Follow local, state, and federal requirements for hazardous chemical waste
UN Number: 1993 (Flammable Liquid, n.o.s.)
Transport Class: 3 (Flammable liquid)
Packaging: Use leakproof, flame-resistant bottles, keep upright and away from incompatible goods
Labelling: Class 3 (Flammable) label required
Emergency Response: Keep emergency spill kit and fire extinguishers ready during transport
US Regulations: Not specifically listed under SARA Title III, TSCA inventory, or CERCLA. Flammability puts it under local fire safety rules
Global Inventories: Registered in key inventories such as EINECS (EU), DSL (Canada), AICS (Australia)
Label Requirements: GHS signal word “Warning”, hazard and precautionary statements, supplier contact info required under OSHA GHS standards
Other Standards: Subject to requirements for safe chemical handling under workplace safety acts
