Chemical Name: 2-Acetyl Pyrrole
Synonyms: 1H-Pyrrole, 2-acetyl-; 2-Pyrrolyl methyl ketone
Molecular Formula: C6H7NO
Molecular Weight: 109.13 g/mol
CAS Number: 1072-83-9
Recommended Use: Laboratory chemical, intermediate in synthesizing pharmaceuticals, flavor compound
Supplier Contact: Manufacturer information available on product label
Emergency Phone Number: Refer to local regulatory guidelines for country-specific numbers
GHS Classification: Flammable liquid (Category 4), Acute oral toxicity (Category 4), Eye irritation (Category 2A)
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, harmful if swallowed, combustible liquid, may cause drowsiness or dizziness
Pictograms: Exclamation mark, Flame
Precautionary Statements: Avoid breathing vapors, use only outdoors or in well-ventilated areas, keep away from heat/sparks/open flames, store in a cool place
Potential Health Effects: Inhalation may cause respiratory tract irritation, ingestion can lead to gastrointestinal discomfort, prolonged skin contact may result in dermatitis
Chemical Name: 2-Acetyl Pyrrole
Purity: 98% or higher (typical for research use)
Concentration: 100% (single ingredient substance)
Impurities: Trace pyrrole derivatives or solvents, rarely present at more than 0.1%
Skin Contact: Rinse immediately with soap and water for at least 15 minutes, remove contaminated clothing and wash before reuse
Eye Contact: Flush gently with copious amounts of water for at least 15 minutes, keep eyelids apart, seek medical help if irritation persists
Inhalation: Move into fresh air, allow victim to rest, monitor for symptoms such as headache or nausea, get medical attention if breathing difficulty continues
Ingestion: Do not induce vomiting unless instructed by medical personnel, rinse mouth with water thoroughly, seek medical advice, never give anything by mouth to an unconscious person
Notes for Physician: Symptomatic and supportive care, monitor airway and respiratory function, treat skin and eye irritation conservatively
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray (cooling action only)
Hazards from Fire: Vapors may form explosive mixtures with air at higher concentrations, emits toxic and irritating fumes (e.g., nitrogen oxides, carbon monoxide) during combustion
Protective Equipment: Wear self-contained breathing apparatus and full protective clothing
Special Procedures: Move containers from affected area if possible and safe, use water spray to cool fire-exposed surfaces, prevent firewater runoff from entering drains
Personal Precautions: Don protective gloves, goggles, chemical-resistant apron; ensure adequate ventilation, eliminate potential ignition sources
Environmental Precautions: Do not allow to enter drains or watercourses, contain spill with absorbent material
Cleanup Methods: Absorb with earth, sand, or inert absorbent, scoop material into labeled chemical waste containers, wash area with water and detergent after material is picked up
Reporting: Notify local authorities according to regulations if spill contaminates environment
Handling: Work in a fume hood or in well-ventilated conditions, avoid skin or eye contact, wash hands after handling, keep containers tightly sealed when not in use, no smoking near chemical
Storage: Store in a cool, dry, and well-ventilated location; keep away from sources of ignition and incompatible substances (strong oxidizers, acids), protect from direct sunlight, use UN-approved containers
Incompatibilities: Strong acids and oxidizing agents, sources of open heat or flame
Exposure Limits: Not established by OSHA, NIOSH, ACGIH
Engineering Controls: Laboratory fume hood, explosion-proof ventilation recommended, safety shower and eyewash station nearby
Personal Protective Equipment: Chemical-resistant gloves (nitrile, neoprene), safety goggles or face shield, lab coat or chemical-resistant apron, vapor respirator under high airborne levels
Hygiene Measures: Wash hands thoroughly after handling, avoid eating and drinking in areas where material is handled
Appearance: Pale yellow to amber crystalline solid or liquid at room temperature
Odor: Distinct, pleasant, nutty, bready smell
Odor Threshold: Low, detectable at parts-per-million
pH: No data available (neutral in water)
Melting Point: 31–34°C
Boiling Point: 237–239°C
Flash Point: 93°C (199°F, closed cup)
Evaporation Rate: Not determined
Flammability: Combustible
Upper/Lower Flammability Limits: Not established
Vapor Pressure: 0.051 mmHg at 25°C
Vapor Density: 3.8 (air = 1)
Density: 1.09 g/cm³ at 25°C
Solubility: Slightly soluble in water; miscible with alcohol, ether, chloroform
Partition Coefficient (log Pow): Calculated 0.33
Autoignition Temperature: No data available
Decomposition Temperature: Not specified
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Not highly reactive in normal conditions, may react with strong oxidizers
Conditions to Avoid: Heat, flames, sparks, direct sunlight, incompatible materials
Hazardous Decomposition Products: Produces carbon oxides, nitrogen oxides, possibly toxic pyrrole derivatives on combustion
Acute Toxicity: LD50 (oral, rat) ≈ 326 mg/kg
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Symptoms: Eye and skin irritation, drowsiness, central nervous system effects, gastrointestinal discomfort
Chronic Effects: Prolonged or repeated exposure may cause dermatitis; no evidence of carcinogenicity, mutagenicity, reproductive toxicity under typical exposure conditions
Sensitization: Not reported in animal or human studies
Toxicity to Aquatic Life: Expected low to moderate toxicity, insufficient data for full classification
Persistence/Degradability: Limited rapid biodegradation in aquatic environments, may persist under anaerobic conditions
Bioaccumulation: Potential low bioaccumulation (log Pow under 1)
Mobility in Soil: Slightly mobile due to moderate water solubility
Other Harmful Effects: At spill concentrations, could affect water quality and aquatic organisms
Waste Treatment Methods: Handle through licensed chemical waste disposal contractor, incinerate under controlled conditions
Disposal of Containers: Triple rinse and puncture before discarding, comply with local hazardous waste regulations
Precautions: Do not allow waste into drains or natural water sources, store waste in permitted chemical waste storage area
UN Number: Not regulated as hazardous material for transport (verify with latest IATA, IMDG, ADR guidelines)
Proper Shipping Name: 2-Acetyl Pyrrole
Transport Hazard Class: Not assigned
Packing Group: Not assigned
Special Transport Notes: Use original, tightly sealed container, keep away from food and feedstuffs, prevent spillage during transport
Federal Regulations: Not listed as hazardous substance under TSCA, SARA Title III, or CERCLA
OSHA Status: Non-hazardous by definition of Hazard Communication Standard, but chemical hygiene recommended
State Regulations: Not subject to California Proposition 65
International Inventories: Listed in EINECS/ELINCS (European Union), confirmed in Korea, Japan, China inventories
Labeling Requirements: Follow workplace labeling laws for chemical hazards and safe handling, refer to CLP/GHS requirements outside the US
