Chemical Name: 2-Acetopyrrole
Synonyms: 1H-Pyrrol-2-yl ethanone, 2-Acetylpyrrole
CAS Number: 1072-83-9
Molecular Formula: C6H7NO
Molecular Weight: 109.13 g/mol
Manufacturer/Supplier: List of chemical suppliers or labs supplying synthetic compounds
Recommended Uses: Often used for research in organic chemistry, flavor manufacturing, intermediate building block
Emergency Contact: Local poison control centers or manufacturer's emergency lines; sometimes researchers keep local fire department info at hand
Classification: Irritant to eyes and skin, moderate inhalation hazard, low chronic toxicity
Signal Word: Warning
Hazard Statements: Can cause irritation to skin, mucous membranes, eyes; inhalation of vapors may cause respiratory irritation or headache; ingestion may lead to gastrointestinal upset
Pictograms: Exclamation mark (GHS07)
Precautionary Statements: Avoid breathing dust or vapor, wear chemical splash goggles, impervious gloves, work in ventilated area
Other Hazards: Combustible at elevated temperatures, avoid sources of static discharge, may form irritating fumes if burned
Chemical Ingredient: 2-Acetopyrrole
Concentration: 98%+ in commercial and research samples
Impurities: Unreacted pyrrole, minor water traces, no stabilizers typically added
Additives: None included
Inhalation: Move person to fresh air, support breathing if needed, seek professional medical assistance if symptoms persist; people with asthma, allergies, or prior respiratory issues should take extra care
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with soap and water; if irritation occurs, call a medical professional
Eye Contact: Rinse immediately with clean water for 15 minutes, ensure eyelids are open, seek medical advice quickly because chemical can stick to eye tissue
Ingestion: Rinse mouth, provide water to drink if person is fully alert, avoid giving anything by mouth to an unconscious person, contact poison control or a physician rapidly
Advice to Physicians: Treat symptoms, monitor for respiratory distress, rinse exposed surfaces thoroughly
Suitable Extinguishing Media: Dry chemical powder, foam, carbon dioxide; use water spray only for a fine mist as direct stream spreads chemical
Specific Hazards & Products of Combustion: Fire produces toxic fumes like carbon oxides and nitrogen oxides, closed containers may rupture in heat
Protective Equipment for Firefighters: Self-contained breathing apparatus, chemical-protective clothing, keep barrels cool with water sprays if present
Special Instructions: Eliminate ignition sources, prevent water runoff from contaminating nearby water supplies
Personal Precautions: Evacuate area, wear gloves and goggles, ventilate space, avoid inhaling vapor
Environmental Precautions: Prevent entry into drains and water systems, contain with absorbent materials
Cleanup Methods: Scoop up with non-sparking tools; absorb liquid with inert materials—sand, universal absorbent granules, or paper towels sealed in solvent-resistant bags; wash area with plenty of water after
Disposal: Collect waste in chemical disposal containers following local and national guidelines
Handling: Handle in fume hood, avoid open flames, static buildup, sources of ignition; wash hands after handling
Storage: Store tightly sealed in amber glass containers, keep in a cool dry place, separate from oxidizers, acids, bases; label containers with date and content clearly, keep away from strong sunlight
Hygiene Practices: No eating, drinking, or smoking near chemical, clean up work areas and equipment thoroughly after use
Engineering Controls: Use chemical fume hoods, local exhaust ventilation, splash guards or glass screens in open labs
Personal Protective Equipment: Safety goggles with side protection, lab coat, impervious nitrile or neoprene gloves, optional face shields during large transfers
Respiratory Protection: Dust mask if airborne particles suspected; NIOSH-certified organic vapor respirator during spills or heavy use
Environmental Controls: Use closed processes where possible, keep work surfaces and storage areas free of unnecessary chemical clutter
Physical State: Clear to yellowish liquid at room temperature; some batches show slight pink tint on oxidation
Odor: Slightly sweet, nutty, typical of pyrrole derivatives
Melting Point: Approx 18–21°C
Boiling Point: Around 192–195°C
Flash Point: About 72°C
Autoignition Temperature: Not well documented, estimated near 420°C
Density: About 1.06 g/cm³
Solubility: Miscible with ethanol, ether, chloroform; moderately soluble in water
Vapor Pressure: Low at room temperature
pH: Neutral to slightly acidic in aqueous solution
Chemical Stability: Stable under standard conditions, light and heat can speed decomposition
Possible Reactions: Reacts with oxidizers, strong acids and bases, peroxides
Hazardous Decomposition: May produce carbon monoxide, carbon dioxide, NOx gases under combustion
Polymerization: No known tendency for dangerous polymerization
Conditions to Avoid: Avoid heat sources, open flame, direct sunlight
Acute Toxicity: Inhaling vapor may irritate respiratory tract; skin contact causes redness and itch, moderate toxicity by ingestion
Chronic Effects: Repeated exposure dries and cracks skin, may aggravate dermatitis or asthma, animal data suggest low risk of organ damage at low doses
Routes of Exposure: Inhalation, skin absorption, ingestion, eye contact
Symptoms: Headache, nausea, dizziness, coughing, throat dryness
Carcinogenic Status: No data linking 2-Acetopyrrole to cancer in humans or animals
Sensitization: No documented allergic skin reaction in literature, but always possible in sensitive individuals
Toxicity to Aquatic Life: Limited data, assumed moderately hazardous to fish and invertebrates, may disrupt microorganisms in high concentrations
Mobility: Likely to dissolve and move in water if spilled
Persistence: Breaks down somewhat in sunlight and air, can linger in soil or water for days
Bioaccumulation: Not expected to build up in food chains due to low absorption in aquatic organisms
Additional Details: Avoid release to environment, particularly in undeveloped or sensitive aquatic systems
Waste Treatment: Collect and deliver all liquid and solid waste to hazardous chemical disposal vendors
Environmental Precautions: Never flush down drain, do not mix with general garbage
Container Disposal: Triple rinse empty containers, deface labels, dispose with chemical waste according to local laws
Recommended Practices: Label all disposal containers, segregate from general waste, inform disposal handler about contents
UN Number: Not officially assigned
Shipping Name: Laboratory Chemicals, N.O.S. (contains 2-Acetopyrrole)
Hazard Class: Considered non-hazardous for most forms of ground and air shipment in small quantities
Packing Group: III (if considered for bulk transport under local rules)
Transport Precautions: Keep tightly sealed, secure from tipping; do not transport with strong oxidizers, acids, or foodstuffs
OSHA Status: Not listed as hazardous under U.S. OSHA standards
TSCA Status: Appears in U.S. TSCA inventory, permitted for research use
SARA Title III: Not a reportable substance
European Regulation: Compliant under REACH for research and small-scale industrial use, not subject to additional restrictions
Other Global Rules: Transport and use subject to local chemical hygiene plans and environmental controls everywhere
