Product Name: 2,6-Dimethylmorpholine
Synonyms: N/A
Chemical Formula: C6H13NO
Molecular Weight: 115.18 g/mol
CAS Number: 6365-48-6
Recommended Use: Used in chemical synthesis, polymer processing, and as a solvent in specialty applications.
Manufacturer Contact: Emergency phone numbers and addresses must be with packaging supplied from chemical distributors or local suppliers.
GHS Classification: Flammable liquid (Category 3); Acute toxicity, oral (Category 4); Skin irritation (Category 2); Eye irritation (Category 2A)
Pictogram(s): Flame, Exclamation mark
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor. Harmful if swallowed. Causes skin and eye irritation.
Precautionary Statements: Avoid breathing vapors. Use in a well-ventilated area. Keep away from ignition sources. Wear gloves and protective eyewear. Wash hands thoroughly after handling. Do not eat, drink or smoke when using product.
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact.
Chemical Identity: 2,6-Dimethylmorpholine
CAS: 6365-48-6
Concentration: 98% or higher
Impurities: Small amounts of other dimethylmorpholine isomers, water content typically less than 1%.
Inhalation: Move to fresh air. Seek medical attention if breathing difficulties occur. Remove contaminated clothing.
Skin Contact: Rinse with plenty of water for several minutes. Remove contaminated clothing. Get medical advice if irritation or symptoms persist.
Eye Contact: Rinse with water for fifteen minutes. Lift upper and lower eyelids occasionally. Seek immediate medical help if redness or pain continues.
Ingestion: Rinse mouth. Do not induce vomiting unless directed by medical personnel. Call a poison center or doctor immediately.
Most Important Symptoms: May include burning sensation, headache, nausea, and skin redness. Symptoms can develop quickly with concentrated exposure.
Medical Attention: Detailed case-specific management by healthcare professionals may be needed for significant exposures.
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, or water spray for small fires. Larger fires may require alcohol-resistant foam.
Hazardous Combustion Products: Carbon dioxide, carbon monoxide, nitrogen oxides, toxic vapors.
Special Protective Equipment: Firefighters need self-contained breathing apparatus and full protective gear.
Fire Hazards: Vapors can form explosive mixtures with air. The liquid’s low flash point adds to fire risk near open flames or hot surfaces.
Advice for Firefighters: Use water spray to cool exposed containers. Isolate hazard area. Prevent water runoff from entering sewers or waterways.
Personal Precautions: Keep away from sources of ignition. Evacuate unnecessary personnel. Use personal protective equipment including gloves, goggles, and, where appropriate, respirators.
Methods for Containment: Stop leak if safe to do so. Dike with sand or earth to prevent spread.
Cleanup Methods: Absorb with inert material (dry sand, earth, or vermiculite), then scoop into a suitable container. Wash spill area after pick-up.
Environmental Precautions: Avoid allowing material to enter drains, surface water, or soil. Notify authorities in case of significant environmental discharge.
Handling: Use in a well-ventilated place. Do not handle near heat, sparks, or open flames. Avoid prolonged or repeated exposure. Wear suitable protective clothing, gloves, and eye/face protection.
Storage: Store in tightly closed containers in a cool, dry, well-ventilated area, away from direct sunlight and incompatible substances such as strong oxidizers and acids.
Incompatible Materials: Acids, oxidizing agents, chlorine, and strong reducing agents.
Other Precautions: Ground and bond containers and receiving equipment. Prevent static discharge.
Occupational Exposure Limits: No OSHA PEL or ACGIH TLV established, but airborne exposure must be minimized.
Engineering Controls: Local exhaust ventilation. Enclosed process equipment where appropriate. Emergency eye wash stations and safety showers recommended.
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), splash goggles or safety glasses, long-sleeved lab coat or protective suit, and chemical-resistant footwear.
Respiratory Protection: Use respirators if ventilation is insufficient or for large spills.
Hygiene Measures: Wash hands, forearms, and face thoroughly after handling. Change contaminated clothing before re-use.
Appearance: Colorless to pale yellow liquid
Odor: Amine-like
Odor Threshold: Not determined
pH: Alkaline (in solution)
Melting Point/Freezing Point: -15 °C
Boiling Point: 163 °C at 760 mmHg
Flash Point: 52 °C (closed cup)
Evaporation Rate: Not available
Flammability: Flammable
Vapor Pressure: 1.2 mmHg at 25 °C
Vapor Density: Heavier than air
Relative Density: 0.91-0.93 g/cm³
Solubility: Miscible with water
Partition Coefficient (log Pow): Not available
Auto-ignition Temperature: 270 °C
Decomposition Temperature: Not specified
Viscosity: Not determined
Chemical Stability: Stable under recommended storage conditions.
Reactivity: Tends to react with strong oxidizing agents, acids, and acid chlorides.
Hazardous Reactions: May react with strong oxidizers to produce heat, toxic gases.
Conditions to Avoid: High temperatures, open flames, ignition sources, and incompatible chemicals.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, small amounts of other toxic vapors.
Routes of Exposure: Absorption by inhalation, skin, eyes, and ingestion.
Acute Toxicity: LD50 (oral, rat) estimated to be 300-2000 mg/kg. Skin irritation possible with contact. Inhalation of higher vapor concentrations may cause symptoms such as dizziness or headaches.
Skin and Eye Irritation: Causes skin and eye irritation. Extended or repeated contact may strengthen symptoms.
Sensitization: No reliable data indicating skin sensitization.
Mutagenicity/Carcinogenicity: No data for long-term exposure in humans or animals.
Reproductive Toxicity: No reports of reproductive harm under normal conditions of use.
Chronic Exposure: Inhalation or skin contact over time could cause organ effects or dermatitis.
Ecotoxicity: Data limited. Expected to be moderately toxic to aquatic organisms based on structure.
Persistence and Degradability: Not expected to persist in the environment. Likely to hydrolyze or biodegrade in aerobic conditions.
Bioaccumulative Potential: Low. Water solubility suggests minimal bioaccumulation in aquatic organisms.
Mobility in Soil: Expected to migrate through soil due to water solubility.
Other Adverse Effects: Avoid large spills to waterways. Even low concentrations could damage aquatic life.
Waste Treatment Methods: Burn in an approved chemical incinerator, following all local and national regulations. Use a licensed waste disposal company.
Contaminated Packaging: Rinse container with water, then triple rinse before disposal. Follow guidelines for hazardous waste containers.
Environmental Caution: Do not release into drains or environment. Residue from containers poses risk until properly cleaned.
Special Precautions: Check for region-specific disposal requirements, especially regarding amines or volatile organic compounds.
UN Number: UN 1993
UN Proper Shipping Name: Flammable liquid, n.o.s. (2,6-Dimethylmorpholine)
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: III
Environmental Hazards: Not marine pollutant as per current regulations; confirm locally.
Transport Precautions: Carry in tightly sealed, properly labeled containers. Protect from physical damage or extreme temperatures. Emergency response guide for transport incidents must be available.
US Regulations: Not found on US TSCA list as a regulated substance, but state regulation or reporting may apply.
European Union: Classification and labeling as per REACH, CLP Regulation. Not listed on Annex XIV or XVII restrictions.
Other Countries: Check local workplace safety and environmental regulations. Canada DSL/NDSL, Australia AICS, and Japan ENCS list coverage varies.
Chemical Safety Assessment: Risk assessment for handling in industrial settings advised. Ensure workers receive training on hazards and control measures.
