Product Name: 2,5-Dimethyl-1H-Pyrrole
Synonyms: 2,5-Dimethylpyrrole
Chemical Formula: C6H9N
Molecular Weight: 95.14 g/mol
CAS Number: 625-82-1
Manufacturer: Sourcing this compound often involves specialty chemical suppliers focusing on research-grade materials. Contact information, emergency telephone numbers, and details for obtaining further product safety documentation usually appear on the original supplier’s packaging.
GHS Classification: Flammable liquid (Category 3), Acute toxicity oral (Category 4), Eye irritation (Category 2A), Skin irritation (Category 2)
Signal Word: Warning
Hazard Statement(s): Flammable liquid and vapor. Harmful if swallowed. Causes skin irritation and eye irritation.
Pictograms: Flame, Exclamation mark
Precautionary Statement(s): Keep away from heat. Avoid breathing vapors or mist. Wear protective gloves and eye/face protection. Wash thoroughly after handling.
Chemical Name: 2,5-Dimethyl-1H-Pyrrole
Concentration: ≥99%
Impurities: May include traces of related methylpyrroles, solvents, or pyrrole analogs, usually less than 1%
Other Identifiers: EC Number 210-891-6
Inhalation: Move person to fresh air and keep at rest in a position comfortable for breathing. If breathing problems develop, seek medical attention immediately.
Skin Contact: Remove contaminated clothing. Gently wash affected skin with water and mild soap for at least 15 minutes. Medical attention might be needed if irritation or rash persists.
Eye Contact: Hold eyelids open and rinse continuously with water for 15 minutes. Remove contact lenses if present and easy to do, then continue rinsing. Medical attention remains necessary if irritation continues.
Ingestion: Rinse mouth. Do not induce vomiting. Drink water if conscious. Call a poison control center or physician without delay.
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical powder, carbon dioxide, or water spray. Avoid high-pressure water j ets which might spread the fire.
Special Hazards: Emits toxic fumes of nitrogen oxides and carbon oxides under combustion. Vapors may form explosive mixtures with air.
Advice for Firefighters: Wear self-contained breathing apparatus and protective clothing. Remove chemicals from fire area if safe.
Further Information: Keep away from drains or runoff to minimize environmental impact.
Personal Precautions: Avoid breathing vapors. Wear chemical splash goggles, lab coat, gloves, and proper foot protection. Remove sources of ignition.
Environmental Precautions: Prevent spillage from entering drains, sewers, or watercourses. Notify local authorities if significant amounts enter the environment.
Methods for Cleanup: Absorb small spills with non-combustible absorbent material (sand, earth, or vermiculite). Scoop into labeled, sealable containers. For large leaks, dike hazard area. Ventilate zone well before reentry. Dispose of residues in accordance with local regulations.
Handling: Use only in well-ventilated areas, ideally under a chemical fume hood. Avoid direct contact with skin, eyes, and clothing. Do not inhale vapors. Prevent build-up of static electricity by grounding containers and equipment.
General Hygiene: Wash hands, arms, and face thoroughly after use. Remove contaminated clothing and launder before reuse.
Storage: Store tightly capped in a cool, dry, well-ventilated place away from direct sunlight and incompatible materials such as strong oxidizers and acids. Keep away from ignition sources. Maintain containers upright and labeled.
Occupational Exposure Limits: No official occupational exposure limit set by OSHA, NIOSH, or ACGIH as of now.
Engineering Controls: Strong local exhaust ventilation and fume hoods reduce vapor exposure risk. Use explosion-proof equipment in likely vapor zones.
Personal Protective Equipment: Chemical-resistant gloves (nitrile, neoprene), tightly fitting safety goggles, flame-resistant lab coat, and closed-toe shoes. In case of inadequate ventilation, use a NIOSH-approved organic vapor respirator. Facilities should have an eyewash station and emergency shower available nearby.
Appearance: Colorless to pale yellow liquid
Odor: Distinct amine-like, pungent aroma
Melting Point: -18°C
Boiling Point: 158-160°C
Flash Point: 45°C (closed cup)
Flammability: Flammable liquid and vapor
Density: 0.93 g/cm³ (at 25°C)
Solubility: Slightly soluble in water, soluble in common organic solvents such as ethanol, ether, and acetone
Vapor Pressure: 1.4 mmHg (at 25°C)
Auto-ignition Temperature: Not established
Explosive Limits: Not fully established
Partition Coefficient (Log Kow): Around 1.45
Chemical Stability: Stable under recommended storage conditions when moisture and air are minimized. Sensitive to light and air, so containers must remain sealed.
Conditions To Avoid: Exposure to heat, sparks, open flames, air, and sunlight. Prolonged exposure to moisture induces hydrolysis and polymerization.
Incompatible Materials: Strong oxidizers, acids, acid chlorides, anhydrides. Avoid mixing with halogenated compounds.
Hazardous Decomposition Products: Burning produces toxic gases like carbon monoxide, carbon dioxide, and nitrogen oxides.
Acute Toxicity: LD50 (oral, rat): 210 mg/kg as reported in select toxicology sources.
Routes of Exposure: Absorption through inhalation, ingestion, and skin contact possible.
Symptoms: Eye, skin, and respiratory tract irritation observed. Risk of drowsiness, headaches, and dizziness at higher concentrations. Swallowing causes nausea and stomach discomfort.
Chronic Effects: Limited long-term data, but continuous exposure might sensitize skin. Not enough evidence for carcinogenicity or mutagenicity.
Medical Conditions Aggravated by Exposure: Individuals with prior allergies, skin, or respiratory disorders may carry heightened risk of adverse effects.
Ecotoxicity: No full-scale aquatic toxicity data available, though structurally-similar compounds exhibit moderate toxicity to fish and invertebrates.
Persistence and Degradability: Probably biodegradable through standard microbial soil processing, but data remains limited.
Bioaccumulative Potential: Expected low due to modest Log Kow value, though no chronic bioaccumulation results published.
Mobility in Soil: Moderate mobility in soil and sediment predicted due to partial water solubility.
Other Adverse Effects: Avoid release to the environment. Collect and treat effluent, limit discharge to surface waters.
Waste Treatment Methods: Incinerate at a licensed chemical disposal facility observing local, regional, and national regulations.
Container Disposal: Triple rinse empty containers with appropriate solvent, then destroy by puncturing or incinerating. Do not reuse containers for food or drink storage.
Special Precautions: Accumulate wastes in dedicated labeled containers. Consult with environment, health, and safety authority before landfill disposal.
UN Number: 1993
UN Proper Shipping Name: Flammable liquid, n.o.s. (contains 2,5-Dimethyl-1H-Pyrrole)
Transport Hazard Class(es): 3 (Flammable liquid)
Packing Group: III
Environmental Hazards: None reported for small quantities. Emergency response guidelines suggest spill containment and notification to authorities for larger releases.
Special Precautions for User: Secure container with absorbent padding. Notify carrier of hazards. During air transport, consult current IATA guidelines.
OSHA Status: Considered hazardous by OSHA Hazard Communication Standard (29 CFR 1910.1200).
TSCA (Toxic Substances Control Act): Listed for research and development purposes,
SARA Title III Sections 302/304/313: Not listed as an extremely hazardous or toxic chemical.
California Proposition 65: Not listed as a known carcinogen or reproductive toxin as of the latest evaluation.
Other Regulations: Users must follow all local, state, and national guidelines regarding storage, use, transport, and disposal. Occupational health and safety rules require risk assessments for any new use.
Chemical Safety Assessment: Not completed for quantities above laboratory scale.
