Product Name: 2-(4-Methylthiazol-5-Yl)Ethanol
Synonyms: 4-Methyl-5-thiazolylethanol
CAS Number: 65619-52-9
Use: Intermediate in chemical synthesis, research, flavor and fragrance applications
Supplier: Refer to local distributor for sourcing information
Contact Information: Emergency numbers and contact details given on manufacturer’s website or label
Restrictions: Industrial, laboratory, not for direct human consumption
Recommended Use: Analytical reagent, research and development, chemical production
Classification: Eye irritant, respiratory irritant
Signal Word: Warning
Hazard Statements: May cause eye and skin irritation, possible respiratory tract discomfort, can generate harmful fumes if heated
Pictograms: Exclamation mark (GHS07)
Precautionary Statements: Avoid breathing dust or vapor, use only outdoors or in well-ventilated area, wash hands thoroughly after handling, use personal protective equipment as required
Potential Health Effects: Irritation to eyes, skin, respiratory and digestive systems on direct exposure; prolonged or repeated exposure may result in dermatitis or sensitization
Chemical Name: 2-(4-Methylthiazol-5-Yl)Ethanol
Chemical Formula: C6H9NOS
Purity: ≥98% (typical lot tested)
Impurities: Trace levels of related thiazole compounds
Molecular Weight: 143.21 g/mol
EC Number: 613-305-2
Inhalation: Move to fresh air, seek medical attention if symptoms develop, keep the victim warm and at rest
Skin Contact: Remove contaminated clothing, rinse area thoroughly with soap and water, consult a physician if irritation persists
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, remove contact lenses, get medical help if discomfort continues
Ingestion: Rinse mouth with water, do not induce vomiting, seek immediate medical attention
Most Important Symptoms: Throat and eye irritation, burning sensation, possible headache; in case of significant exposure, respiratory distress or persistent skin reactions require prompt care
Suitable Extinguishing Media: Dry chemical, CO2, water spray, alcohol-resistant foam
Unsuitable Media: Direct water jet in confined spaces
Special Hazards: May produce sulfur oxides, nitrogen oxides, toxic gases under fire conditions
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Advice for Firefighters: Evacuate area, control run-off water to prevent environmental contamination, cool containers exposed to heat with water spray, prevent inhalation of combustion fumes
Personal Precautions: Avoid breathing vapors, eliminate ignition sources, ventilate the area, wear protective clothing, gloves, and safety goggles
Environmental Precautions: Prevent entry into waterways, sewers, and soil, notify authorities if large spills occur
Methods for Clean-Up: Absorb with inert material (sand, earth), sweep up, transfer to labeled containers for disposal, wash spill site after material pickup
Emergency Procedures: Evacuate non-essential personnel, keep unprotected persons away, ensure spill area remains well-ventilated until cleaning is finished
Handling: Avoid contact with skin, eyes, and clothing; prevent formation of aerosols; do not ingest or inhale; use in fume hood or with local exhaust
Storage Conditions: Store in a tightly closed, properly labeled container in a cool, dry, and well-ventilated place
Incompatible Materials: Strong oxidizers, acids, alkali metals
Storage Temperature: 2–8°C recommends safe shelf life; keep away from direct sunlight and heat sources
General Hygiene: No eating, drinking, or smoking in work area; wash hands after handling and before breaks
Engineering Controls: Provide adequate ventilation, preferably chemical fume hood; install eyewash stations and safety showers
Respiratory Protection: If risk of vapor or dust, use NIOSH-approved respirator
Skin Protection: Chemical-resistant gloves (nitrile, neoprene); long-sleeved work clothing
Eye/Face Protection: Safety glasses with side shields or chemical splash goggles
Other Protection: Remove contaminated clothes immediately and launder before reuse, keep personal items separate from work attire
Exposure Limits: No ACGIH or OSHA exposure limits established, but minimize exposure as best practice
Appearance: Pale yellow to off-white crystalline powder
Odor: Faint, sulfurous, thiazole-like
pH: Neutral (aqueous solution)
Melting Point: 49–52°C
Boiling Point: No data available; decomposition may occur before boiling
Solubility: Soluble in water, methanol, ethanol; limited solubility in non-polar solvents
Vapor Pressure: Low, not measured directly
Partition Coefficient (log Kow): Estimated as low to moderate, based on structure
Flashpoint: No test data, typically over 100°C
Density: Approx. 1.2 g/cm3
Chemical Stability: Stable under recommended storage conditions, sensitive to strong oxidizers
Reactivity: Does not react dangerously under normal conditions
Hazardous Reactions: None reported under recommended handling and storage; hazardous decomposition possible with contact to strong acids or oxidizers
Decomposition Products: Nitrogen oxides, sulfur oxides, carbon monoxide, carbon dioxide under fire or extreme heat
Acute Toxicity: No published LD50 for humans or rodents; expected low acute toxicity
Irritation: Causes eye, skin, and respiratory irritation on direct exposure
Sensitization: No reports of systemic sensitization, minor risk for people with prior chemical allergies
Chronic Effects: Not rated for carcinogenicity, mutagenicity, or teratogenicity by IARC, NTP, or EPA; prolonged or repeated contact increases risk for dermatitis
Possible Symptoms: Cough, shortness of breath, redness, and dryness after prolonged or intense contact
Aquatic Toxicity: No specific data, treat as potentially harmful to aquatic life
Persistence and Degradability: May degrade slowly in environment, breakdown affected by microbial activity
Bioaccumulation Potential: Estimated low; structure does not favor biomagnification
Mobility in Soil: Likely moderate, could migrate if released in large quantities
Other Adverse Effects: Prevent bulk release to sewers, surface, or groundwater; follow local environmental regulations
Waste Disposal Methods: Dispose through licensed chemical waste contractor; do not drain to sewer system
Contaminated Packaging: Empty containers must be handled as hazardous waste; decontaminate before recycling or incineration
Legal Requirements: National and local environmental legislation must be met; keep waste labeling clear and complete
UN Number: Not assigned
UN Proper Shipping Name: Not regulated for transport under ADR, RID, IMDG, IATA
Transport Hazard Class: Not classified as hazardous for air, sea, or road
Packing Group: Not assigned
Special Precautions: Ship in sealed, upright, and well-labeled containers, keep away from incompatibles, prevent cargo shifting and spillage
EU Regulations: Registered under REACH, not listed as candidate substance of very high concern
US Regulations: Not found on TSCA, CERCLA, SARA 313
Labeling Requirements: Comply with OSHA Hazard Communication Standard, GHS pictograms required
Other Information: Users must ensure compliance with import, use, and disposal restrictions applicable in their region
