Product Name: 2,3-Diethyl-5-Methyl Pyrazine
Chemical Formula: C9H14N2
Chemical Family: Alkylpyrazine
CAS Number: 18138-04-0
Recommended Use: Flavoring agent, chemical intermediate
Supplier: Contact information for chemical supplier or manufacturer
Emergency Contact Number: Provided by manufacturer
GHS Classification: Eye irritation, Skin irritation, Specific target organ toxicity – single exposure
Signal Word: Warning
Hazard Statements: Causes mild to moderate eye irritation. May cause skin irritation on heavy or repeated contact. Can affect central nervous system if inhaled in high concentrations.
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust, fumes, gas, mist, vapors, spray. Wash thoroughly after handling. Use personal protective equipment as required.
Potential Health Effects: Shortness of breath, dizziness, headache, skin redness, eye discomfort. Prolonged exposure could lead to respiratory irritation.
Environmental Hazards: Harmful to aquatic life with long-lasting effects.
Chemical Name: 2,3-Diethyl-5-Methyl Pyrazine
CAS Number: 18138-04-0
Concentration: >98% by weight
Impurities: Trace amounts of structurally related alkylpyrazines possible, contributing less than 2% combined
Inhalation: Move person to fresh air. Seek medical attention if symptoms persist. Remove source of exposure.
Skin Contact: Remove contaminated clothing immediately. Wash skin with soap and water for several minutes. If irritation appears or persists, contact a healthcare provider.
Eye Contact: Rinse opened eyes gently with water for at least 15 minutes. Remove contact lenses if present. Get medical help if irritation continues.
Ingestion: Rinse mouth out with water. Do not induce vomiting unless told to by a medical professional. Seek immediate assistance if large amounts swallowed or symptoms occur.
Most Important Symptoms: Drowsiness, breath shortness, eye redness, skin irritation, headache.
Notes for Physicians: Treat symptoms. No specific antidote known.
Suitable Extinguishing Media: Carbon dioxide, foam, dry chemical powder. Use water spray for cooling containers.
Unsuitable Extinguishing Media: Direct water jet can spread burning material.
Hazardous Combustion Products: Nitrogen oxides (NOx), carbon monoxide, carbon dioxide, other toxic gases.
Special Protective Equipment for Fire-Fighters: Full face self-contained breathing apparatus and chemical protective suit.
Fire and Explosion Hazards: Vapors may form explosive mixture with air. Containers can explode when heated. Stay away from the area and keep upwind.
Personal Precautions: Isolate the area and ventilate. Avoid contact with skin, eyes, and clothing. Prevent inhalation of vapors.
Protective Equipment: Chemical resistant gloves, eye protection, coveralls, and suitable respirator for large spills.
Spill Clean-up Methods: Absorb with inert non-combustible material (sand, diatomaceous earth), place in container for disposal. Wash area with water after material pickup. Dispose of all collected materials following local requirements.
Environmental Precautions: Prevent from entering drains, sewers, waterways. Notify relevant authorities if material enters environment.
Handling: Use in well-ventilated area. Wear recommended protective gear. Avoid direct contact or inhalation. Prevent spills and leaks. Do not eat, drink, or smoke while handling.
Storage: Store in tightly sealed containers, away from sunlight, moisture, and sources of ignition. Keep in cool, dry, well-ventilated space. Segregate from oxidizers and acids. Protect from physical damage. Clearly label all containers.
Incompatible Materials: Strong oxidizing agents, acids
Storage Temperature: 5–25°C recommended.
Occupational Exposure Limits: No established limits in US OSHA, ACGIH. Handle as potentially hazardous.
Engineering Controls: Use fume hood or adequate local exhaust to limit airborne concentrations. Eyewash and safety shower available near handling area.
Personal Protective Equipment: Nitrile or neoprene gloves, safety goggles or face shield, protective clothing, suitable respirator when airborne concentration is elevated.
Hygiene Measures: Remove contaminated clothing, wash hands and face after work.
Appearance: Clear to pale yellow liquid
Odor: Roasted, nutty aroma
Odor Threshold: Distinct, low-level detection
pH: Not applicable (non-aqueous)
Melting Point: -20°C (approximate)
Boiling Point: 210–215°C
Flash Point: 89°C (closed cup)
Evaporation Rate: Not established
Flammability: Combustible
Vapor Pressure: Low at room temperature
Vapor Density: >1 (air=1)
Relative Density: ~0.95 g/cm³
Solubility: Negligible in water, soluble in organic solvents
Partition Coefficient (log Kow): Estimated 2.5–3.5
Auto-Ignition Temperature: 360°C
Decomposition Temperature: Above 200°C
Viscosity: Low to moderate
Chemical Stability: Stable under normal conditions. Sensitive to strong acids and oxidizers. Protect from excessive heat or flame.
Hazardous Reactions: Vigorous reaction with oxidizing agents.
Conditions to Avoid: Heat, open flames, sparks, direct sunlight, incompatible materials.
Hazardous Decomposition Products: Combustion or decomposition releases toxic fumes of nitrogen oxides, carbon monoxide, carbon dioxide.
Polymerization: Not expected under standard handling or storage conditions.
Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion.
Acute Toxicity: Low acute oral and dermal toxicity. May cause discomfort or minor irritation.
Skin Corrosion/Irritation: Mildly irritating to skin with repeated exposure.
Serious Eye Damage/Irritation: May cause eye redness and watering.
Respiratory Sensitization: Not a known sensitizer, possible irritation if mist or vapor inhaled.
Carcinogenicity: Not identified as carcinogen by IARC, NTP, OSHA.
Reproductive Toxicity: No available data suggest reproductive effects.
Chronic Effects: Prolonged or excessive exposure could contribute to central nervous system depression.
LD50 (oral, rat): >2000 mg/kg (estimate, not experimentally determined)
Ecotoxicity: Moderately toxic to aquatic life; avoid direct release to environment.
Mobility in Soil: Low water solubility and moderate partition coefficient mean moderate tendency to adsorb to soil.
Persistence and Degradability: Not readily biodegradable in standard tests.
Bioaccumulation Potential: Moderate log Kow suggests possibility of bioconcentration in aquatic organisms.
Other Environmental Hazards: May cause long-term adverse effects in aquatic habitats.
Waste Disposal: Dispose via licensed chemical waste contractor. Comply with all local, regional, national, and international regulations. Small amounts can be neutralized then flushed into chemical sewer only with appropriate permits.
Contaminated Packaging: Triple rinse and offer clean container for recycling or incineration. Do not reuse empty packaging for other substances.
Special Precautions: Avoid discharge to surface water or sewers.
UN Number: Not regulated as hazardous for ground, sea or air transport (check national regulations).
UN Proper Shipping Name: Not classified
Transport Hazard Class: Not allocated
Packing Group: Not assigned
Special Precautions for User: Prevent spills during transport by securing container and avoiding rough handling.
Environmental hazards: Harmful to aquatic organisms. Take care to prevent accidental release during transit.
OSHA: Not specifically regulated
SARA Section 313: Not listed
TSCA Inventory: Present
REACH Status (EU): Subject to registration
Other Relevant Regulations: Not restricted under US EPA or EU regulations. All users must still observe general chemical safety and environmental protection laws applicable in their region.
Labeling Requirements: GHS hazard pictogram and statements on containers handling or storing more than laboratory-scale amounts.
