Material Safety Data Sheet (MSDS) for 2,3-Dibromothiophene

Identification

Product Name: 2,3-Dibromothiophene
Chemical Formula: C4H2Br2S
CAS Number: 3141-27-3
Synonyms: Dibromothiophene, α,β-Dibromothiophene
Recommended Uses: Organic synthesis, pharmaceutical research, chemical intermediate
Supplier Details: Name, address, and emergency contact number of the manufacturer or supplier

Classification: Harmful if swallowed or inhaled; causes skin and eye irritation; potential aquatic hazard
Signal Word: Warning
Hazard Statements: Harmful to aquatic life, causes moderate eye and skin irritation, may trigger respiratory discomfort if vapors are inhaled, not flammable but can generate hazardous gases above certain temperatures
Pictograms: Exclamation mark, environment
Precautionary Statements: Avoid contact with skin, eyes, and clothing. Avoid breathing dust or fumes. Use adequate ventilation. Avoid release into the environment.

Chemical Identity: 2,3-Dibromothiophene
Purity: 98% or higher, minor impurities include water and trace polybrominated byproducts
Other Components: None of significant hazard or secondary ingredients, no additives reported as contaminants at known levels

Inhalation: Move person to fresh air, loosen tight clothing, offer oxygen if breathing difficulty arises, seek medical help if symptoms persist
Skin Contact: Wash affected area with soap and water for at least 15 minutes, remove contaminated clothing, seek medical advice for irritation or rash
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, consult a doctor if redness or pain remains
Ingestion: Rinse mouth, do not induce vomiting unless directed by medical personnel, seek immediate medical attention
Notes for Physician: Provide symptomatic and supportive treatment, monitor respiratory and skin symptoms

Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Hazards from Combustion: Release of toxic fumes including bromine, hydrogen bromide, sulfur oxides, and carbon oxides possible in fire
Protective Equipment: Wear self-contained breathing apparatus and full protective gear
Special Procedures: Contain runoff from fire-fighting as it may carry hazardous material, keep containers cool with water spray

Personal Precautions: Wear chemical-resistant gloves, goggles, lab coat, use proper respirator in areas with inadequate ventilation, avoid all sources of ignition
Spill Response: Contain spill with sand or inert absorbent, shovel into labeled containers for disposal, wash spill area thoroughly with detergent and water
Environmental Precautions: Avoid spillage into waterways or sewers, report substantial releases to appropriate local authorities
Cleanup Methods: Ventilate area, use non-sparking tools, collect solid or liquid carefully to minimize dust or vapor generation

Handling: Keep container tightly closed, avoid breathing dust or vapor, wash hands thoroughly after handling, use in a fume hood or well-ventilated area
Storage Conditions: Store at room temperature in a well-ventilated dry area, keep away from oxidizers and moisture, secure containers against tipping or breakage, post warning labels in all storage locations
Incompatible Substances: Avoid strong oxidizing agents, strong acids, and bases; do not store near foodstuffs or animal feed

Engineering Controls: Work in a chemical fume hood or with local exhaust ventilation, maintain eyewash stations and safety showers nearby
Respiratory Protection: Use NIOSH-approved respirators for organic vapors if engineering controls are insufficient
Skin Protection: Chemical-resistant gloves (nitrile or better), protective clothing, closed-toe shoes
Eye Protection: Tightly fitting goggles or face shield
Hand Washing: Wash hands thoroughly after each use, especially before eating or drinking
Hygiene Measures: Do not eat, drink, or smoke during use, handle with care to avoid exposure

Appearance: Pale yellow to light brown liquid
Odor: Sharp, irritating
Molecular Weight: 241.94 g/mol
Melting Point: -15 °C (approximate)
Boiling Point: 192–194 °C
Flash Point: >80 °C
Solubility: Insoluble in water, soluble in most organic solvents like ethanol, diethyl ether, chloroform
Vapor Pressure: Low, precise value not widely published
Density: 2.11 g/cm³ at 20 °C

Chemical Stability: Stable under recommended storage conditions, decomposition may begin above 200 °C
Reactivity: Non-reactive under standard lab conditions, reacts with strong oxidizers or bases
Hazardous Decomposition: HBr, SOx, and toxic brominated organics may form during extreme heating or combustion
Polymerization: Does not undergo dangerous polymerization under normal conditions

Acute Toxicity: Oral (rat) LD50 not precisely established; component chemicals indicate moderate acute oral and dermal toxicity
Skin Contact: Can cause moderate irritation, redness, and burning sensation
Inhalation: Vapors and mists irritate respiratory tract, can provoke coughing, soreness, and shortness of breath
Eye Contact: Irritation, redness, or burning may appear on exposure
Chronic Effects: No long-term studies; theoretical risk for respiratory or organ damage similar to other halogenated thiophenes
Sensitization: Sensitization rare, possible in sensitive individuals

Ecotoxicity: Toxic to aquatic organisms (fish and daphnia), avoid release to lakes and rivers
Mobility: Low water solubility, likely to partition to soil or sediment
Persistence/Degradability: Breakdown in environment not rapid, long-term persistence possible
Bioaccumulation: Elevated risk due to lipophilicity, potential to accumulate in aquatic organisms
Additional Hazards: Even small spills may disrupt water systems, so extra care during disposal or cleanup is important

Waste Disposal: Gather waste in sealed labeled containers, send to authorized chemical disposal facility
Do Not: Pour into drains, bury in soil, or release to environment
Container Disposal: Triple rinse empty containers, remove or deface labels, forward for chemical drum recycling or proper landfill
Regulatory Compliance: Comply with local, regional, and national hazardous waste regulations; consult local authorities for detailed procedures

UN Number: 2810
Shipping Name: Toxic liquid, organic, n.o.s. (contains 2,3-dibromothiophene)
Transport Hazard Class: 6.1 (toxic substances)
Packing Group: III
Labels Required: Toxic, Environmental Hazard
Special Precautions: Protect containers against physical damage, handle shipments by road, air, or sea in chemical transport containers approved for hazardous substances

TSCA: Listed
EINECS: 221-551-8
REACH: Pre-registered, check status for registration deadlines if importing into EU
OSHA: Considered hazardous under OSHA criteria, workplace exposure limits not established but caution still required
California Proposition 65: Not currently listed, users should verify updates for state-specific restrictions
Other Notes: Local chemical safety and workplace hygiene rules apply, check national chemical substance inventories for compliance in target countries