Product Name: 2.3.4.5-Tetrahydrothiophene
CAS Number: 110-01-0
Synonyms: Tetrahydrothiophene, THT, Thiacyclopentane
Recommended Use: Used as solvent, used for organic synthesis, intermediate for pharmaceuticals and as odorizing agent for natural gas
Manufacturer: [Supplier Information / Contact Details]
Emergency Contact: [Emergency phone number, accessible 24 hours]
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Classification: Flammable liquid, irritant, harmful by inhalation or skin contact
Hazard Statements: May cause eye, skin, and respiratory tract irritation; combustible liquid and vapors; may cause headaches or dizziness in poorly ventilated spaces
Precautionary Statements: Keep away from heat, sources of ignition, no smoking near product; avoid breathing vapors or mist; wash exposed skin thoroughly after handling; use only outdoors or in well-ventilated area
Signal Word: Warning
Symbol: Flame, Exclamation Mark
Chemical Name: 2.3.4.5-Tetrahydrothiophene
Common Name: THT
CAS Number: 110-01-0
Concentration: 99+% (Pure Substance, may contain trace stabilizers or processing aids)
Impurities: None of regulatory significance
Inhalation: Move affected person to fresh air, keep comfortable for breathing; give oxygen if breathing is difficult; call doctor if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin gently with soap and water; seek medical attention if irritation develops or persists
Eye Contact: Rinse eyes carefully with plenty of water for at least 15 minutes, lift eyelids occasionally, remove contacts if present and easy; consult physician
Ingestion: Rinse mouth, never give anything by mouth to unconscious person; do not induce vomiting, seek medical help immediately; observe for symptoms of nausea, headache, dizziness
Suitable Extinguishing Media: Foam, dry chemical, carbon dioxide, sand; water spray for cooling containers; avoid high-pressure water jet
Specific Hazards: Vapors may form explosive mixtures with air, thermal decomposition releases toxic and irritating fumes including sulfur oxides
Protective Equipment: Firefighters need self-contained breathing apparatus and full protective clothing
Fire-Fighting Instructions: Isolate area, remove containers from path of fire if safe, cool closed containers with water spray; remain upwind to avoid hazardous fumes
Personal Precautions: Evacuate unnecessary personnel, ventilate area, avoid breathing vapors, prevent contact with skin or eyes, wear appropriate PPE
Environmental Precautions: Prevent spilled product from entering drains, sewers, or waterways
Cleanup Methods: Contain spill with non-combustible material, absorb with sand or vermiculite; collect for disposal in labeled container; wash area with plenty of water
Handling: Avoid inhalation and contact with eyes, skin, or clothing; open container with caution; use with sufficient ventilation; ground and bond containers during transfer
Storage: Store in tightly sealed original container, in a cool, dry, well-ventilated area; keep away from direct sunlight, heat sources, sparks, and open flames; segregate from strong oxidizers and acids; keep out of reach of children and unauthorized users
Exposure Limits: No established occupational exposure limit (consult local regulations for guidelines)
Engineering Controls: Use local exhaust ventilation, explosion-proof equipment, maintain good general room ventilation
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), safety goggles with side shields, flame-retardant lab coat, use appropriate respirator if ventilation is not adequate, safety shoes; wash hands before breaks and after work; do not eat or drink near work area
Appearance: Colorless to pale yellow liquid
Odor: Strong, unpleasant, sulfurous, garlic-like smell
Odor Threshold: Very low (highly odorous at low concentrations)
pH: Not applicable
Melting Point: -110°C
Boiling Point: 121–122°C
Flash Point: 21–27°C (closed cup)
Evaporation Rate: Not available
Flammability: Flammable
Upper/Lower Explosion Limits: 1.5–7.0% (vol) in air
Vapor Pressure: 25 mmHg @ 25°C
Vapor Density: 2.6 (air = 1)
Relative Density: 0.98 g/cm³ @ 20°C
Solubility: Slightly soluble in water, miscible with organic solvents
Partition Coefficient (log Kow): 1.86
Auto-ignition Temp: 255°C
Decomposition Temp: Not determined
Viscosity: Not significant
Chemical Stability: Stable under recommended handling and storage conditions
Incompatible Materials: Strong oxidizing agents, acids, bases; contact may cause rapid exothermic reaction or hazardous decomposition
Hazardous Polymerization: Not expected to occur
Decomposition Products: Thermally breaks down to release sulfur oxides, carbon oxides, irritating sulfur-containing gases
Conditions to Avoid: Open flames, heat, sources of ignition, high temperatures, contact with incompatible chemicals
Likely Routes of Exposure: Inhalation, skin absorption, eye contact, ingestion
Acute Effects: May cause irritation to respiratory tract, eyes, skin; inhalation may lead to dizziness, headache, nausea
Chronic Effects: No chronic toxicity data reported for humans; high repeated exposure may cause liver, kidney, CNS effects in experimental animals
LD50 (Oral, Rat): Approx. 1600 mg/kg
LD50 (Dermal, Rabbit): Approx. 2000 mg/kg
LC50 (Inhalation, Rat): Not precisely determined, expected to be moderately toxic
Carcinogenicity: Not listed as carcinogen by IARC, NTP, OSHA
Mutagenicity: Not expected to be mutagenic
Reproductive Effects: No data available
Ecotoxicity: Harmful to aquatic organisms, may cause long-term adverse effects in aquatic environment; fish LC50 (96h) >100 mg/L
Persistence and Degradability: Not considered readily biodegradable; persists in environment if released in large amounts
Bioaccumulation: Log Kow suggests low to moderate bioaccumulation
Mobility in Soil: Low to moderate mobility; much will volatilize if released to soil
Other Adverse Effects: Spills may generate strong odor complaints over wide areas
Waste Disposal: Treat as hazardous chemical waste; incinerate in a chemical incinerator equipped with afterburner and scrubber; do not dispose down drain, into surface water, or landfill
Container Disposal: Triple rinse empty container, puncture and dispose in accordance with local, regional, national, and international regulations; do not reuse container
Additional Information: Consult licensed waste disposal contractor for proper handling
UN Number: UN 2414
UN Proper Shipping Name: Tetrahydrothiophene
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: II
Environmental Hazards: Not classified as Marine Pollutant, but take care to avoid releases
Special Precautions for Users: Keep away from open flames, sources of ignition during transport; ensure container integrity and appropriate labeling; follow regulations for flammable substances during ground, sea, or air shipping
OSHA: Classified as hazardous under OSHA Hazard Communication Standard
TSCA: Listed in the US Toxic Substances Control Act Inventory
SARA Title III: Sections 302 (No), 304 (No), 311/312 (Fire Hazard, Immediate Health Hazard), 313 (No)
REACH: Registered substance; comply with restrictions and exposure scenarios
WHMIS (Canada): Class B2 Flammable Liquid, D2B Toxic
Other Regulations: Check local, state, or provincial regulations for additional restrictions or requirements concerning flammable and hazardous substances
