Product Name: 2-(2-Chloroethyl)-1-Methylpiperidine
Chemical Formula: C8H16ClN
Synonyms: N-Methyl-2-(2-Chloroethyl)piperidine
CAS Number: 6761-86-2
Recommended Use: Research, synthesis, intermediate for pharmaceuticals or specialty chemicals
Restrictions: Not for food, drug, or residential use
Manufacturer Details: Supplier and emergency contact information provided per label
Emergency Telephone: Chemtrec and national poison control hotline supplied on product packaging
Date of Issue: Updated per recent revision of safety protocols
Classification: Acute toxicity (oral, dermal, inhalation), skin/eye irritant, potential carcinogen
Signal Word: Danger
Hazard Statements: Harmful if swallowed or inhaled, causes skin and eye irritation, may cause respiratory irritation
Pictograms: Skull and crossbones, exclamation mark
Precautionary Statements: Avoid release to environment, do not breathe dust or vapors, wear protective gloves, eye and face protection, wash hands thoroughly after handling
Health Hazards: Irritation of skin, eyes; vapors may cause dizziness, headache, nausea; prolonged contact may cause burns
Environmental Hazards: Toxic to aquatic life, can cause long-term adverse effects in the environment
Chemical: 2-(2-Chloroethyl)-1-Methylpiperidine
CAS Number: 6761-86-2
Concentration: 98% or higher purity
Impurities: Minor residual solvents under 1%, trace unreacted starting materials from synthesis, not significant to toxicity profile
Eye Contact: Rinse cautiously with running water for at least 15 minutes, remove contact lenses if present, seek medical attention immediately
Skin Contact: Wash skin with copious water and mild soap, remove contaminated clothing immediately, seek medical help for persistent irritation
Inhalation: Remove person to an area with fresh air, monitor for breathing and pulse, administer oxygen if available, seek prompt medical evaluation
Ingestion: Rinse mouth thoroughly, do not induce vomiting, never give anything by mouth to an unconscious person, get immediate medical advice
Main Symptoms: Irritation, chemical burns to affected area, cough, dizziness, headache, nausea
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, alcohol-resistant foam. Water spray can be used for cooling
Unsuitable Media: Direct water jet can spread chemical or increase hazard
Hazards from Combustion: Releases toxic fumes of hydrogen chloride, nitrogen oxides, carbon oxides
Protective Equipment: Self-contained breathing apparatus, chemical resistant suit
Special Procedures: Isolate hazardous area, prevent run-off, keep upwind to avoid fumes
Personal Precautions: Evacuate unnecessary personnel, wear chemical splash goggles, gloves, and protective clothing
Environmental Precautions: Keep out of drains and sewers, prevent entry into environment
Cleanup Methods: Small spills absorbed with inert material such as sand or earth, collect and place in labeled waste containers for disposal, ventilate area thoroughly, wash spill site after material pick-up
Decontamination: Use alkaline soap and copious water on contaminated surfaces, properly dispose of used clean-up materials
Safe Handling: Use only in fume hood or well-ventilated area, avoid direct contact with skin or eyes, do not ingest, handle with grounded equipment
Hygiene Measures: Do not eat, drink, smoke during use, wash hands and face after handling
Storage Conditions: Store in tightly closed, clearly labeled containers, in a cool, dry, well-ventilated place away from incompatible materials (e.g., oxidizers, strong acids), protect from light and moisture
Specific End Use: Used by trained professionals under controlled laboratory or industrial conditions
Exposure Limits: No specific occupational exposure limits assigned; minimize concentration in air where possible
Engineering Controls: Local exhaust ventilation, emergency eyewash and shower facilities
Personal Protection: Chemical-resistant gloves (nitrile or neoprene), full splash goggles, lab coat or full chemical suit, closed shoes
Respiratory Protection: Suitable respirator when vapor or mist present; use approved cartridge respirators or PAPR for organic vapors
Environmental Controls: Prevent contamination of soil, water, and air through careful management
Appearance: Clear to pale yellow liquid
Odor: Slightly amine-like, pungent
Odor Threshold: Not established
pH: No data available
Melting Point: Below room temperature
Boiling Point: Estimated range 215–225 °C
Flash Point: Over 85 °C (closed cup)
Evaporation Rate: Not rapid under ambient conditions
Flammability: Not highly flammable, may ignite at elevated temperatures
Vapor Pressure: Low at room temperature
Vapor Density: Greater than air
Relative Density: 0.98–1.02 (water = 1)
Solubility: Soluble in organic solvents, low in water
Partition Coefficient: log Kow expected above 1
Decomposition Temperature: Over 200 °C
Viscosity: Moderate, similar to other alkylamines
Chemical Stability: Stable under recommended storage conditions, does not polymerize
Reactivity: Reacts vigorously with strong oxidizing agents, may react with acids to form toxic chlorinated organics
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, other toxic chlorine-containing gases
Incompatible Materials: Strong acids, oxidizers, acid chlorides, anhydrides
Conditions to Avoid: Excessive heat, open flame, contact with incompatible substances
Routes of Exposure: Inhalation, ingestion, dermal, eye contact
Acute Toxicity: Oral LD50 (rat): expected between 50–500 mg/kg, can be fatal in large doses
Chronic Toxicity: No conclusive long-term animal studies, may present risk of organ damage with prolonged exposure
Skin Corrosion/Irritation: Causes irritation and possibly burns, based on analog data for related piperidines
Serious Eye Damage: Severe irritation, risk of permanent eye injury from direct contact
Respiratory Sensitization: May cause coughing, sneezing, and discomfort on inhalation
Carcinogenicity: Not established but possible due to alkylating activity
Mutagenicity: Not enough data, handle as potentially mutagenic
Signs and Symptoms: Local pain, inflammation, redness, tearing, headache, dizziness
Ecotoxicity: Harmful to aquatic organisms, risk of bioaccumulation not fully known
Persistence and Degradability: Not readily biodegradable, expected to persist in soil and water for extended periods
Bioaccumulative Potential: Potential for accumulation in aquatic species, partition to organic matter in aquatic systems
Mobility in Soil: Moderately adsorbed, risk of leaching to groundwater
Other Adverse Effects: May contribute to chemical oxygen demand (COD) in water bodies, negative impact on plant, algae, and invertebrate populations
Waste Treatment Methods: Collect all waste in sealed, properly labeled containers
Incineration: Incinerate at high temperature in a licensed chemical waste facility equipped with afterburner and scrubber
Contaminated Packaging: Decontaminate empty containers with suitable detergent and water before disposal or recycling
Environmental Precautions: Never dispose of by flushing down drains or release into environment, comply with local hazardous waste disposal regulations
Special Considerations: Notify local waste authorities for collection and safe destruction
UN Number: UN 2810 (for toxic liquids, organic, n.o.s.)
Shipping Name: Toxic liquid, organic, n.o.s. (contains 2-(2-Chloroethyl)-1-Methylpiperidine)
Transport Hazard Classes: 6.1 (toxic substance)
Packing Group: II (medium danger)
Labels Required: Toxic (skull and crossbones), environmentally hazardous
Environmental Hazards: Marine pollutant
Transport Precautions: Keep upright, secure, away from incompatible materials, only trained personnel should handle
Regulations: Follows IATA, IMDG, ADR, and domestic DOT requirements
Safety: Subject to OSHA workplace safety regulations, PPE requirements
Environmental: EPA hazardous substance, restrictions on release to waterways
Inventory Status: Listed or notified under TSCA in the United States, REACH in Europe may require registration
Other Regulations: SARA Title III reporting may apply for facilities storing large amounts
Workplace Restrictions: Restricted access for untrained personnel, full compliance with chemical hygiene plan mandatory
Labeling Requirements: GHS compliant hazard and precautionary symbol use required
International: Classified as hazardous for international trade and shipping purposes
