Product Name: 2,2,6,6-Tetramethylpiperidin-4-ol
Chemical Formula: C9H19NO
Synonyms: 4-Hydroxy-2,2,6,6-tetramethylpiperidine
CAS Number: 2403-88-5
Recommended Use: Used as an organic intermediate, antioxidant in polymers, and stabilizer in industrial chemistry
Manufacturer Contact: [Insert manufacturer and emergency telephone number]
Emergency Overview: White to pale yellow solid, faint amine-like odor, not considered volatile under standard conditions
GHS Classification: Skin irritation (Category 2), Eye irritation (Category 2A), Specific target organ toxicity – single exposure (Category 3)
Pictogram: Exclamation mark
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, may cause respiratory irritation
Precautionary Statements: Wash thoroughly after handling, use only in a well-ventilated area, wear protective gloves/eye protection, avoid breathing dust
Potential Health Effects: Inhalation can irritate upper respiratory tract, contact with skin or eyes can result in redness, itching, or pain, ingestion causes gastrointestinal discomfort
Chemical Name: 2,2,6,6-Tetramethylpiperidin-4-ol
CAS Number: 2403-88-5
EC Number: 219-307-4
Concentration: ≥ 97%
Impurities: Trace amounts of related piperidine derivatives may be present, typically under 1% collectively
Formulation: Solid, crystalline or powder
Stabilizer added: None, pure compound
Inhalation: Move exposed individual away from source, supply fresh air, keep at rest, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with water, use mild soap if available, monitor for irritation, get medical help for any persistent redness or blistering
Eye Contact: Flush eyes immediately with running water for at least 15 minutes, remove contact lenses if present and easy to do, continue rinsing, obtain medical attention if discomfort or visual disturbance develops
Ingestion: Rinse mouth, drink water if alert, never induce vomiting unless directed by medical personnel, get medical advice promptly
Notes for Physicians: Treat symptomatically and supportively, no specific antidote known, monitor for delayed respiratory or gastrointestinal effects
Suitable Extinguishing Media: Use carbon dioxide, dry chemical, alcohol-resistant foam, or water spray/water fog
Unsuitable Extinguishing Media: Direct streams of water may spread burning material
Hazards From Combustion Products: Emits toxic fumes, especially nitrogen oxides and carbon monoxide, during thermal decomposition
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full turnout gear
Fire/Explosion Risk: Not highly flammable, but dust in air can create explosion hazard when exposed to ignition sources; keep containers cool with water spray
Advice For Firefighters: Approach upwind, use standard fire-fighting procedures, contain runoff to avoid environmental impact
Personal Precautions: Evacuate unnecessary personnel, avoid contact with skin, eyes, and clothing, ensure adequate ventilation
Protective Equipment: Wear suitable protective clothing including gloves, safety goggles, and dust mask or respirator
Environmental Precautions: Prevent product from entering drains, watercourses, or soil, notify authorities if significant spillage reaches environment
Spill Cleanup Methods: Collect solid material mechanically, avoid raising dust, use absorbent material for residues, place in suitable container for disposal
Decontamination: Wash spill area with water and detergent, ventilate area thoroughly after cleanup
Safe Handling Recommendations: Avoid breathing dust, use only with sufficient ventilation, minimize dust generation, do not eat, drink, or smoke when handling
Personal Hygiene: Wash hands and face after use, launder contaminated clothing regularly
Storage Conditions: Store in tightly closed container, keep in a dry, cool, well-ventilated area, avoid exposure to moisture, heat, direct sunlight, and oxidizers
Compatibility: Incompatible with strong acids, oxidizers, and certain metal salts
Special Instructions: Avoid stacking heavy items on containers, label storage clearly, keep away from sources of ignition
Exposure Limits: No specific occupational exposure limits established, minimize exposure as a general rule
Engineering Controls: Use local exhaust ventilation, contain handling processes to prevent dust, install eyewash stations and safety showers
Personal Protective Equipment: Wear chemical-resistant gloves (nitrile or neoprene), safety goggles or face shield, laboratory coat or chemical apron, NIOSH-approved respirator if dust likely present
Monitoring Procedures: Periodic air monitoring for dust concentrations near workstations recommended for large-scale use
Environmental Controls: Prevent particulate release into air and drains, use secondary containment in sensitive areas
Thermal Hazards: Use heat-resistant gloves if transferring at high temperatures
Appearance: White to pale yellow crystalline solid
Odor: Faint amine-like
Odor Threshold: Not established
pH (in solution): ~10 (1% in water)
Melting Point/Freezing Point: 61-65°C
Boiling Point/Range: Approx. 227°C at 760 mmHg
Flash Point: Over 95°C (closed cup)
Evaporation Rate: Not volatile under standard conditions
Flammability: Not easily ignited, dust is combustible
Vapor Pressure: <0.01 mmHg at 20°C
Vapor Density: Not applicable (non-volatile solid)
Relative Density: 0.95 g/cm³
Solubility: Slightly soluble in water, freely soluble in alcohol and acetone
Partition Coefficient (n-octanol/water): Not available
Autoignition Temperature: Data not available
Decomposition Temperature: Above 200°C
Viscosity: Not applicable (solid)
Chemical Stability: Stable under recommended storage conditions
Reactivity: Not reactive under normal conditions, avoid strong oxidizers and acids
Conditions to Avoid: High temperatures, direct sunlight, moisture, contact with incompatible materials
Possibility of Hazardous Reactions: Violent reaction with strong oxidizers; decomposition generates toxic gases in fire
Hazardous Decomposition Products: Emits nitrogen oxides, carbon monoxide, carbon dioxide upon combustion
Polymerization: Not expected to occur
Acute Toxicity: Ingestion or inhalation of significant quantities causes irritation of gastrointestinal tract or respiratory passages; oral LD50 (rat) estimated above 2000 mg/kg
Skin Corrosion/Irritation: Repeated or prolonged contact leads to skin dryness or cracking, risk of dermatitis
Serious Eye Damage/Irritation: Causes transient eye irritation, may result in redness, watering, and discomfort
Respiratory or Skin Sensitization: No data on sensitization from industrial use, low likelihood reported
Chronic Exposure: No data to suggest long-term toxicity or carcinogenicity
Other Effects: Not mutagenic or teratogenic in available testing
Medical Conditions Aggravated By Exposure: Persons with sensitive skin or respiratory issues could experience mild exacerbation
Ecotoxicity: Low toxicity to aquatic organisms expected based on chemical structure; no specific fish or daphnia toxicity data
Persistence and Degradability: Not readily biodegradable, slow natural breakdown in environment
Bioaccumulative Potential: Not expected to bioaccumulate significantly in food chains due to water solubility and molecular size
Mobility in Soil: Moderate mobility through soil depending on rainfall and organic content
Other Adverse Effects: Large releases may cause localized contamination of watercourses
Precautions: Avoid discharge into natural waterways, comply with local regulations on chemical use and disposal
Waste Disposal Methods: Collect and place material in labeled containers, incinerate under controlled conditions complying with local and national regulations
Contaminated Packaging: Rinse and neutralize before disposal, consult local authorities for guidance
Recommended Disposal Agency: Licensed hazardous waste handler
Special Precautions for Landfill or Incineration: Avoid release to water, landfill only if incineration not feasible; never discharge to sewer
Recycling Options: Where possible, recover unused product for use in non-critical applications or research
UN Number: Not regulated by road, air, or sea under standard chemical shipping lists
Transport Hazard Class: Not classified as hazardous for transport
Packing Group: Not applicable
Labeling Requirements: None under GHS or DOT for small quantities; use clear identification for bulk transport
Environmental Hazards: Not a marine pollutant
Special Transport Precautions: Secure containers, avoid excessive movement or damage, store away from foodstuffs and animal feeds during transport
Safety, Health and Environmental Regulations: Not subject to major chemical inventories as a controlled substance, commonly listed in TSCA (US), REACH (EU), or similar databases
OSHA/EU GHS Classification: Non-flammable solid, labeled as irritant under GHS
Label Elements: Signal word “Warning”, hazard pictogram “exclamation mark”, standardized precautionary statements
SARA/Title III Reporting: Not listed as extremely hazardous
California Proposition 65: Not included as carcinogen or reproductive toxin
WHMIS: Classified as moderate health hazard in Canada
Other National Requirements: Users should follow local occupational health and safety rules, reference product-specific advisories, and ensure applicable workplace training
