Product Name: 1-Propylpyrrolidine
Chemical Formula: C7H15N
Synonyms: N-Propylpyrrolidine, Pyrrolidine, 1-propyl-
CAS Number: 4570-67-6
Recommended Uses: Laboratory chemical, industrial synthesis, specialty solvent
Supplier Information: Available from most chemical suppliers handling specialty organic bases. Emergency contact numbers are usually given on the physical label or the supplier's website.
Classification: Flammable liquid, Harmful if swallowed or inhaled, Skin and eye irritant
Signal Word: Warning
Hazard Statements: May cause irritation to skin, eyes, and respiratory tract. Vapors may form explosive mixtures with air. Harmful effects can follow if significant exposure is not controlled. No evidence of carcinogenicity in typical exposure.
Pictograms: Flame, exclamation mark
Precautionary Statements: Wear gloves and goggles, operate in ventilated areas, avoid direct skin contact.
Chemical Name: 1-Propylpyrrolidine
Concentration: > 98%
Impurities: Trace organic bases (usually less than 1%)
EC Number: 224-947-2
Inhalation: Move to fresh air, keep at rest, monitor for persistent symptoms like breathing difficulty, seek medical care for significant exposure.
Skin Contact: Remove contaminated clothing, flush skin with running water for minimum 15 minutes, scrub with mild soap if irritation appears, seek medical attention for persistent redness.
Eye Contact: Rinse thoroughly with water for at least 15 minutes, lift eyelids occasionally, get medical attention if irritation remains.
Ingestion: Do not induce vomiting, rinse mouth, drink water if conscious, seek immediate medical advice.
Notes for Physicians: Symptomatic treatment, monitor for chemical pneumonitis or allergic reaction if exposures are significant.
Suitable Extinguishing Media: Use dry chemical powder, alcohol-resistant foam, or carbon dioxide. Water spray can cool exposed containers, but may not be effective for extinguishing.
Specific Hazards: Vapors may travel along ground and flash back, dense smoke and toxic nitrogen oxides may come off during fire.
Protective Equipment for Firefighters: Full protective gear, self-contained breathing apparatus.
Special Instructions: Avoid inhalation of chemicals released by fire, cool surroundings, do not use direct streams of water on chemical fires.
Personal Precautions: Evacuate area if large spill, vent area, avoid breathing vapors, wear gloves and goggles.
Environmental Precautions: Prevent runoff into drains, waterways, and soil, contain spill with sand or inert absorbent.
Cleanup Methods: Absorb with non-reactive material, place in containers for disposal; wash spill site using detergent and water, ventilate area thoroughly.
Reporting: Notify appropriate authorities in case of major releases or if material enters watercourses.
Safe Handling: Work under local exhaust or fume hood, minimize splash and vapor creation, keep away from open flames and hot surfaces, handle with nitrile gloves and chemical goggles.
Storage Requirements: Store in tightly closed containers in cool, ventilated, dry area away from incompatible substances like oxidizers and acids; label containers clearly, avoid storing above room temperature for long periods.
Incompatibilities: Strong oxidizers, acids, alkylating agents.
Other Precautions: Ground and bond containers during transfer, keep out of reach of untrained personnel.
Exposure Limits: No specific occupational exposure limits published, but recommended limit: 10 ppm (manufacturer suggestion, based on irritant nature).
Engineering Controls: Use in chemical fume hood or well-ventilated area.
Personal Protection: Safety goggles, gloves (nitrile or butyl), lab coat, in case of inadequate ventilation, wear suitable respirator (organic vapor cartridge).
Hygiene: Wash hands thoroughly after handling, do not eat or drink during use.
Appearance: Clear, colorless to pale yellow liquid
Odor: Amine-like, strong and unpleasant
Melting Point: Below -60°C
Boiling Point: 154-156°C
Flash Point: Estimated 45°C (closed cup)
Evaporation Rate: Moderate
Flammability: Flammable
Solubility: Miscible with water, alcohol, common non-polar solvents
Vapor Density: Heavier than air
Auto-ignition Temperature: Not well established, expected above 200°C
Viscosity: Low
pH (1% Solution): Strongly basic, pH >11
Partition Coefficient (log Kow): Estimated 1-2
Chemical Stability: Stable under recommended storage and handling, sensitive to strong acid, tends to degrade slowly in presence of moisture and air.
Reactivity: Reacts with acids to form salts; reaction with strong oxidizers can cause hazardous decomposition.
Hazardous Decomposition Products: Gives off nitrogen oxides, carbon monoxide, carbon dioxide on combustion or high heat.
Conditions to Avoid: Open flame, heat sources, prolonged exposure to air and humidity.
Likely Routes of Exposure: Inhalation, skin and eye contact, accidental ingestion
Acute Effects: May cause irritation to eyes, skin, mucous membranes, trouble breathing if vapor inhaled.
Chronic Effects: Longer exposure may cause dermatitis or persistent cough in sensitive people.
Acute Toxicity: LD50 (Oral-rat) estimated > 500 mg/kg, LD50 (Dermal-rabbit): not well defined but expected to be higher.
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, OSHA.
Other Data: No reproductive, teratogenic, or mutagenic effects known from animal studies, but data is limited.
Aquatic Toxicity: Expected to be moderately toxic to aquatic organisms, avoid discharge into the environment.
Persistence and Degradability: Biodegradable with sufficient oxygen, tends to degrade in soil and water over days to weeks.
Bioaccumulation: Low to moderate potential for bioaccumulation
Mobility in Soil: Highly mobile due to water solubility, can reach groundwater if released in significant quantity.
Other Environmental Information: May increase local pH of water, potentially hazardous to fish, daphnia at elevated concentration.
Waste Disposal Methods: Dispose through licensed chemical disposal contractor, incinerate in regulatory-compliant facility.
Contaminated Packaging: Empty containers must be rinsed with water and offered for recycling or disposal per local regulations.
Special Precautions: Do not pour down drains, avoid landfilling bulk material, triple rinse drums before discarding.
UN Number: UN 1993
Proper Shipping Name: Flammable Liquid, N.O.S. (1-Propylpyrrolidine)
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: III
Environmental Hazards: Not classified as marine pollutant
Additional Requirements: Use full DOT/ADR/IATA compliant packaging and labeling, keep upright and secured during transit.
Labeling: Requires hazard and precaution statements per OSHA GHS guidelines.
US Regulations: Not listed on TSCA Inventory as a commercial product, import and manufacture need review.
EU Regulations: Needs REACH registration for import/export in large volumes.
Workplace Limits: Employers should follow national worker safety rules.
SARA Title III/EPCRA: Not a reportable substance.
Other Regulatory Data: Custom clearance paperwork should declare chemical identification and hazards.
