Chemical Name: 1-Methylpyrrolidine
Other Names: N-Methylpyrrolidine, NMPy
CAS Number: 120-94-5
Recommended Use: Intermediate for organic synthesis, solvent in laboratories
Supplier: Manufacturer’s full address and contact
Emergency Contact: National chemical safety hotline, company emergency number
Product Code: Manufacturer’s SKU or catalog #
Restrictions: Reserved for industrial and laboratory applications, not for consumer use
Classification: Flammable liquid, irritating to eyes and skin, harmful if swallowed or inhaled
GHS Label Elements: Signal word: WARNING. Pictograms: Flame, Exclamation Mark
Hazard Statements: Causes skin and eye irritation, may cause drowsiness or dizziness, harmful to aquatic life
Precautionary Statements: Avoid breathing vapors, use only outdoors or in well-ventilated areas, take precautionary steps against static discharge
Health Hazards: Potential neurotoxic effects with repeated exposure, headache, nausea, possible skin absorption
Substance: 1-Methylpyrrolidine
Chemical Formula: C5H11N
Concentration: 99%+ upon pure supply
Impurities: Trace water, minor amine by-products, limited to below 1% per supplier specs
Relevant Additives: None for standard analytical or synthetic supply
Inhalation: Move to fresh air, seek medical advice for breathing difficulties
Skin Contact: Remove contaminated clothing, rinse exposed skin with water for 15 minutes, use soap, call physician for persistent irritation
Eye Contact: Rinse with water for several minutes, lifting eyelids, get immediate medical attention if discomfort continues
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical help right away
Symptoms and Effects: Possible headache, nausea, dizziness, skin or eye irritation, high concentrations might cause drowsiness
Advice to Doctor: Symptomatic treatment, support vital functions
Extinguishing Media: Use dry chemical, CO₂, alcohol-resistant foam, or water spray
Unsuitable Extinguishing Media: Direct water jet may spread burning
Specific Hazards: Vapors can form flammable/explosive mixtures with air, combustion produces toxic gases including CO and NOₓ
Protective Equipment: Firefighters should wear self-contained breathing apparatus and chemical-resistant gear
Advice: Cool containers exposed to fire with water spray, evacuate personnel from danger zone
Personal Precautions: Use respiratory protection, avoid inhalation of vapor, remove ignition sources, ventilate area
Environmental Precautions: Prevent from entering drains, waterways, or soil, notify authorities if spillage affects environment
Cleanup Methods: Absorb with inert material like sand or earth, place in suitable closed container for disposal, clean spill area with water and detergent
Decontamination: Avoid direct contact, use gloves and eye protection, ensure proper ventilation during clean-up
Handling: Use in well-ventilated area, wear suitable protective equipment, avoid contact with skin and eyes, keep away from ignition sources
Hygiene Measures: Wash hands after handling, change contaminated clothing promptly, do not eat or drink during use
Storage Conditions: Store in cool, dry place, keep tightly sealed in original container, avoid direct sunlight, keep away from incompatible materials such as strong oxidizers and acids
Storage Range: Maintain in approved flammable liquid storage cabinets if possible, temperature range 2–25°C recommended
Occupational Exposure Limit: No established ACGIH or OSHA TLV, supplier recommends keeping airborne concentrations below detectable levels
Engineering Controls: Fume hoods, explosion-proof ventilators for storage and use
Personal Protection: Chemical-resistant gloves (nitrile or neoprene), safety goggles, lab coat or apron, respiratory protection if ventilation is inadequate
Environmental Controls: Prevent substance from entering drains, use containment to avoid spills
Appearance: Transparent, colorless liquid
Odor: Amine-like, sharp pungent odor
Boiling Point: 92–94°C
Melting Point: -61°C
Flash Point: Approximately 20°C (closed cup)
Flammability: Flammable liquid
Density: 0.85 g/cm³ at 20°C
Vapor Pressure: 41 hPa at 20°C
Solubility: Miscible with water and most organic solvents
pH: Alkaline in water solution
Viscosity: Low
Chemical Stability: Stable under recommended conditions
Conditions to Avoid: Excessive heat, open flames, sources of ignition
Incompatible Materials: Strong acids, oxidizers, alkylating agents
Hazardous Decomposition: Emits toxic fumes of carbon oxides, nitrogen oxides during combustion
Reactivity: Reacts with acid chlorides, strong electrophiles, may attack copper or some plastics over time
Acute Toxicity: LD50 oral (rat): ~400 mg/kg; LD50 dermal (rabbit): Data not fully established, considered harmful
Inhalation: Irritation to respiratory tract, possible CNS effects
Chronic Effects: Prolonged exposure can lead to liver, kidney toxicity, neurologic symptoms
Skin/Eye Contact: Causes irritation, possible burns on prolonged exposure
Sensitization: Not categorized as a sensitizer
Mutagenicity/Carcinogenicity: No adequate human data, not listed as carcinogen by NTP, IARC, OSHA
Aquatic Toxicity: Harmful to aquatic organisms
Persistence and Degradability: Expected to degrade under normal environmental conditions but can accumulate in cases of large spills
Bioaccumulation: Limited bioaccumulation potential but detailed data lacking
Mobility in Soil: High, due to water solubility
Other Adverse Effects: May cause long-term adverse effects in aquatic environments, so avoid discharge to waterways
Waste Handling: Collect in approved containers, label clearly as hazardous chemical waste
Disposal Methods: Incinerate at licensed facility, small amounts can be neutralized with acid and water under controlled conditions
Precautions: Do not pour down drain or landfill, avoid contamination of surface and groundwater
Packaging Cleanup: Triple rinse containers, dispose of rinsate as hazardous waste
UN Number: 2924
Shipping Name: Flammable Liquid, N.O.S. (contains 1-Methylpyrrolidine)
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: II
Labels Required: Flammable Liquid
Special Transport Notes: Secure tightly in upright position, segregate from oxidizing agents, always follow carrier and national regulations for hazardous shipments
OSHA: Classified as hazardous chemical under Hazard Communication Standard
TSCA: Listed in Toxic Substances Control Act Inventory
EU CLP: Classified as flammable and irritant substance
SARA Title III: Not subject to community right-to-know reporting for extremely hazardous substances
Other National Regulations: Observe all applicable local, regional, and international restrictions and reporting requirements
