Product Name: 1-Methyl-4-Chloropiperidine
Chemical Formula: C6H12ClN
CAS Number: 33689-52-6
Synonyms: N-Methyl-4-chloropiperidine
Manufacturer: [Insert Manufacturer’s Name and Contact]
Recommended Use: Research, chemical synthesis
Emergency Contact Number: [Insert Local Emergency Number]
GHS Classification: Acute Toxicity, Skin Irritant, Eye Irritant, Flammable Liquid
Signal Word: Danger
Hazard Statements: Harmful if inhaled or swallowed; causes skin and eye irritation; flammable liquid and vapor; causes respiratory tract irritation
Pictograms: Flame, Exclamation Mark, Health Hazard
Precautionary Statements: Avoid breathing dust or vapors; wear protective gloves, eye and face protection; keep away from heat, sparks, open flames; take precautionary measures against static discharge
Chemical Identity: 1-Methyl-4-Chloropiperidine
Common Name: N/A
Concentration: 100% (if pure substance)
Impurities: Trace piperidine derivatives (may vary by batch)
CAS Number: 33689-52-6
EC Number: [Insert if available]
Inhalation: Move the person to fresh air without delay. Rest, and seek medical attention if symptoms linger or worsen. For dizziness or shortness of breath, oxygen from a trained responder helps until emergency workers arrive.
Skin Contact: Take off contaminated clothing and rinse skin well with plenty of water. Soap helps remove residues. If irritation persists, see a doctor.
Eye Contact: Rinse eyes carefully under running water for at least 15 minutes, keeping eyelids open. Remove contact lenses, if present and easy. Get medical help for any discomfort or visual changes.
Ingestion: Rinse mouth with water but do not induce vomiting. Never give anything by mouth if the person is not fully conscious. Call a poison control center or doctor at once.
Suitable Extinguishing Media: Dry chemical powder, CO2, alcohol-resistant foam
Unsuitable Extinguishing Media: Direct water stream might spread contamination or vapor
Specific Hazards: Vapor may travel and ignite at distant sources; thermal decomposition can give toxic fumes including hydrogen chloride and nitrogen oxides
Protective Equipment: Firefighters suit up with self-contained breathing gear and protective clothing; approach the fire from upwind; keep containers cool with water spray
Personal Precautions: Put on gloves, goggles, and a mask; get unprotected people out; ventilate the spot
Environmental Precautions: Stop spill from reaching drains or water sources
Cleanup Methods: Soak up spill with inert absorbent (sand, vermiculite), scoop into a labeled drum for disposal; wipe the area with water and detergent after bulk removal; any soaked gear goes into hazardous waste
Spill Reporting: Alert local authorities if environmental release is significant
Safe Handling: Work with this chemical in a chemical fume hood; avoid breathing vapors and contact with skin or eyes; keep away from ignition sources; no smoking or open flames
Storage: Store in tightly closed containers in a cool, well-ventilated room designed for flammables; keep out of sunlight, separate from oxidizers, acids, and strong bases; post clear hazard signage
Permissible Exposure Limits: No specific OSHA, NIOSH, or ACGIH limits assigned; minimize exposure
Engineering Controls: Chemical fume hood and exhaust ventilation; use explosion-proof equipment
Personal Protection: Chemical-resistant gloves (nitrile recommended), safety goggles, lab coat, and when vapor levels rise, a respirator with organic vapor cartridges; emergency eye wash and safety showers ready
Appearance: Clear, colorless to straw liquid
Odor: Amine-like, pungent
Melting Point: Not established (typically below room temperature)
Boiling Point: 156-160°C
Flash Point: Approximately 59°C (closed cup)
Evaporation Rate: Not established, but likely moderate
Vapor Pressure: Low to moderate at 20°C
Solubility: Miscible with organic solvents, slightly soluble in water
Density: About 0.96 g/cm³
Partition Coefficient (log Kow): Not widely published
Autoignition Temperature: Data not widely available
Explosive Limits: Not established
Chemical Stability: Stable in closed containers at room temperature, but degrades under strong heating
Reactivity: Reacts with oxidizing agents, strong acids, and bases; can produce hazardous gases
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide
Conditions to Avoid: Heat, sparks, open flames, incompatible chemicals
Polymerization: Does not self-polymerize under normal conditions
Routes of Exposure: Inhalation, skin absorption, eye contact, ingestion
Acute Effects: Irritation to eyes, skin, and respiratory tract; symptoms include burning, coughing, headache, dizziness, nausea
Chronic Effects: Prolonged or repeated exposure could sensitize skin or increase risk of respiratory symptoms
Toxicity Data: Oral LD50 (rat): Not published for this specific compound, may reference data from related piperidines (often low hundreds of mg/kg)
Carcinogenicity/Mutagenicity: Not classified as carcinogen or mutagen by IARC, NTP, or OSHA
Other Effects: At higher concentrations, vapor can depress central nervous system, leading to drowsiness or confusion
Ecotoxicity: Data limited; similar piperidines may harm aquatic organisms at low concentrations
Persistence & Degradability: Expected to degrade slowly, especially in water
Bioaccumulation: Not expected to significantly bioaccumulate due to moderate solubility
Mobility in Soil: Moderate; can migrate under wet conditions
Other Adverse Effects: Keep away from waterways; toxic runoff or accidental spills should get hard containment and cleanup
Waste Handling: Gather all cleanup residues, unused product, and contaminated items; dispose through a licensed hazardous waste service
Contaminated Packaging: Triple rinse, then handle as hazardous waste
Disposal Methods: Do not pour down any drain or mix with other waste streams; incineration at a controlled facility is the safest solution
UN Number: Not specifically assigned; check local/national code for most similar flammable amine
Proper Shipping Name: Flammable Liquid, N.O.S. (contains 1-methyl-4-chloropiperidine)
Hazard Class: 3 (Flammable Liquid)
Packing Group: III
Labels Required: Flammable Liquid
Special Precautions: Ship in tightly sealed containers; keep upright; avoid rough handling or impact; if in doubt, refer to international codes like IMDG or IATA for shipment abroad
Inventory Listings: Not widely listed on US TSCA; may not occur on EINECS, DSL, AICS—check with supplier for updates
SARA/Title III: Not designated as an Extremely Hazardous Substance, but toxic release reporting may apply
OSHA Hazard: Classified hazardous due to flammability and toxicity
Other Regulations: Local licensing for use, storage, and disposal often applies; special notification for large quantities; always check state and municipal requirements in addition to federal law
