Product Name: 1-Methyl-1H-Pyrrole-2,5-Dione Analogue
CAS Number: 5413-05-8
Molecular Formula: C5H5NO2
Synonyms: N-Methylsuccinimide, N-Methyl-2,5-pyrroledione
Recommended Use: Laboratory reagent, intermediate in synthesis
Supplier: Chemical manufacturer or distributor details as applicable
Emergency Contact: Number as furnished by supplier or local authority
Classification: Acute toxicity (oral, dermal, inhalation), Skin irritation, Eye irritation
Signal Word: Warning
Hazard Statements: May cause skin and eye irritation. Harmful if swallowed or inhaled. Possible respiratory system irritation.
Precautionary Statements: Avoid breathing dust, vapors or spray. Wear protective gloves, clothing, and eye/face protection. Wash thoroughly after handling. Do not eat, drink or smoke during handling.
Hazards Not Otherwise Classified: No specific data on long-term hazards reported, but always handle with caution.
Chemical Name: 1-Methyl-1H-Pyrrole-2,5-Dione Analogue
CAS Number: 5413-05-8
Concentration: >98% pure for most laboratory grades
Impurities: May include trace amounts (<2%) of structurally related imides depending on synthesis route or supplier specifications
Inhalation: Remove to fresh air immediately. Keep at rest in a position comfortable for breathing. Seek medical attention if respiratory symptoms develop.
Skin Contact: Wash with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes. Obtain medical attention in case of persistent irritation.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present. Keep rinsing. Seek urgent medical care if irritation or redness continues.
Ingestion: Rinse mouth thoroughly. Do not induce vomiting without medical advice. Get medical help immediately, especially if large amount is swallowed or symptoms arise.
Most Important Symptoms/Effects: Skin redness, irritation; eye pain, possible blurred vision; coughing, shortness of breath from inhalation; gastrointestinal upset if ingested.
Suitable Extinguishing Media: Water spray, foam, dry chemical or CO2 extinguishers. Avoid water streams that might spread material.
Specific Hazards from Chemical: Can emit hazardous fumes of nitrogen oxides and carbon oxides during combustion.
Special Protective Equipment for Firefighters: Full protective clothing and self-contained breathing apparatus.
Firefighting Instructions: Remove containers from fire zone if possible. Prevent fire run-off from contaminating the environment. Keep upwind of fire. Use standard firefighting methods in chemical fire situations.
Personal Precautions: Use personal protective equipment. Avoid dust formation. Ensure adequate ventilation.
Spill Cleanup Methods: Collect and shovel material into container for disposal. Wash spill area thoroughly to remove residue.
Environmental Precautions: Prevent entry into waterways, drains, or soil. Notify authorities if significant quantities enter the environment.
Containment: Use inert absorbent material if needed. Collect all residues as chemical waste.
Handling: Avoid exposure by using proper protection. Prevent inhalation of dust or vapors. Wash hands thoroughly after handling. Do not eat, drink, or smoke in work area.
Storage Conditions: Store in tightly sealed original containers in cool, dry, and well-ventilated location. Protect from light and incompatible substances such as strong oxidizers.
Incompatible Materials: Strong acids, strong bases, oxidizing agents.
Storage Class: Chemical storage – avoid storing near food, beverages, or in residential locations.
Engineering Controls: Use chemical fume hood or local exhaust ventilation to minimize exposure.
Personal Protection: Wear chemical-resistant gloves (nitrile or neoprene recommended), lab coat, and safety goggles. Use suitable respiratory protection (N95, P95, or better) if dust or vapors present.
Hygiene Measures: Wash thoroughly after handling. Launder contaminated clothing before reuse.
Exposure Limits: No OSHA or ACGIH threshold limit values established for this exact analogue; use general nuisance particulate limits for dusts.
Appearance: White to off-white powder or crystalline solid
Odor: Faint, slightly organic
Odor Threshold: Not established
pH: Not available in aqueous solution
Melting Point/Range: 85–88 °C (manufacturer reported range)
Boiling Point: Decomposes before boiling
Flash Point: Not established for this compound
Solubility: Soluble in hot water, dimethyl sulfoxide (DMSO), and organic solvents like ethanol
Partition Coefficient (log Kow): Not determined
Vapor Pressure: Negligible at room temperature
Density: 1.35–1.40 g/cm3
Other Data: Stable at room temperature, may discolor on exposure to air or moisture.
Chemical Stability: Stable under recommended storage conditions. Sensitive to hydrolysis under strong acidic or basic conditions.
Reactivity: No hazardous reactivity expected under normal conditions.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide and carbon dioxide on combustion.
Conditions to Avoid: Heat, flames, sparks, strong acids, and bases. Avoid moisture to prevent degradation.
Polymerization: Not likely under normal handling and storage conditions.
Acute Toxicity Data: No published LD50 for this analogue; structurally similar imides show oral LD50 (rat) 1500–2500 mg/kg
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Symptoms from Exposure: Irritation of mucous membranes, eyes, and skin. Possible mild gastrointestinal effects if swallowed. Inhalation can cause respiratory discomfort.
Chronic Effects: No long-term toxicity data available. Take caution due to lack of full toxicological profile.
Carcinogenicity/Mutagenicity: No data; not listed as a carcinogen by NTP, IARC, or OSHA.
Other Data: Sensitization not reported but handle all analogues with standard safety precautions.
Aquatic Toxicity: No specific information for this analogue. Imides generally show low to moderate toxicity to aquatic organisms.
Persistence and Degradability: Expected to be biodegradable under standard environmental conditions, but specific data lacking.
Bioaccumulation: Not expected to bioaccumulate due to moderate water solubility, but data not confirmed.
Mobility in Soil: Medium mobility due to solubility; avoid contamination of groundwater.
Other Adverse Effects: Prevent chemical from dispersing into environment; no known ozone depletion or endocrine disruption concerns.
Disposal Methods: Dispose of in accordance with local, regional, and national regulations. Incineration in an approved chemical waste facility preferred if permitted.
Contaminated Packaging: Triple-rinse containers before disposal or recycling if possible. Dispose of packaging in accordance with all relevant regulations.
Special Considerations: Do not dispose of down drain or in regular garbage. Collaborate with licensed hazardous waste contractor.
UN Number: Not classified as a hazardous material for transport under most international regulations (DOT, IATA, IMDG), unless specifics of shipment or local laws apply
Proper Shipping Name: Not regulated
Hazard Class: Not applicable
Packing Group: Not applicable
Transport Labels: None required; always keep container tightly closed and properly labeled during transport
Special Precautions: Secure packaging to prevent leaks or spills; avoid transport with incompatible chemicals.
OSHA: Not specifically regulated under US OSHA Hazard Communication Standard; general duty applies.
TSCA Status: For research use, confirm if compound is listed or exempted; supplier usually provides current status.
SARA Title III: Not listed as an extremely hazardous substance. No Section 313 reporting required based on current data.
REACH (EU): Not registered, intended for research and development use only unless otherwise indicated.
WHMIS (Canada): Not classified as hazardous according to current regulations.
Other Regulations: Check local and national requirements relevant to laboratory or workplace use; recommendations may change based on future toxicological findings or environmental policies.
