Product Name: 1-(M-Chlorophenyl)Piperazine
Synonyms: mCPP, meta-Chlorophenylpiperazine
Chemical Formula: C10H13ClN2
CAS Number: 6640-24-0
Recommended Use: Research chemical, chemical intermediate
Manufacturer: Supplier contact information required
Emergency Contact Number: Local poison control or emergency response center
GHS Classification: Acute Toxicity (Oral, Inhalation), Eye Irritation, Skin Irritation
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, may cause respiratory irritation
Pictograms: Exclamation mark
Signal Word: Warning
Precautionary Statements: Avoid breathing dust, wash skin thoroughly after handling, do not eat or drink while using this product, use protective gloves/eye protection
Potential Health Effects: Eye, skin, and respiratory tract irritation; effects on central nervous system reported
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Chemical Name: 1-(3-Chlorophenyl)piperazine
Percent: ≥98% (as research-grade compound)
CAS Number: 6640-24-0
Impurities/Additives: None known in pure form; minor unidentified process-related impurities possible in some batches
Inhalation: Move to fresh air, keep airway open, give oxygen if breathing is difficult, get medical attention
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, consult a physician if irritation develops
Eye Contact: Rinse eyes with water for at least 15 minutes, lift eyelids occasionally, seek immediate medical attention
Ingestion: Rinse mouth with water, do not induce vomiting, contact poison center or physician promptly
Special Notes for Physicians: Symptomatic treatment, monitor for nervous system effects and standard supportive measures
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray
Unsuitable Extinguishing Media: High-pressure water jets
Specific Hazards: Combustible powders can form explosive mixtures with air, toxic gases (hydrogen chloride, nitrogen oxides) may form
Protective Equipment: Self-contained breathing apparatus (SCBA), full protective gear
Firefighting Instructions: Move containers from fire area if safe, keep cool with water spray, prevent runoff into sewers
Personal Precautions: Use appropriate protective equipment including gloves, eyewear, and a lab coat
Environmental Precautions: Prevent spillage from entering drains or water courses
Containment: Isolate area, ventilate, avoid dust formation
Cleanup Methods: Use inert absorbent materials, sweep up and transfer to approved waste containers, wash spill area with water, ventilate
Disposal: Dispose of in line with local regulations and requirements for hazardous chemical waste
Handling: Use in well-ventilated areas, avoid inhalation/ingestion/contact with eyes and skin, minimize dust generation
Storage Conditions: Store in tightly closed containers, cool dry and well-ventilated space, keep away from incompatible materials (oxidizing agents), label area as hazardous
Other Precautions: Prevent unauthorized access, store separate from food and drink, handle using approved chemical management protocols
Exposure Limits: None established for product; control dust and vapors to lowest possible level
Engineering Controls: Chemical fume hood, local exhaust recommended
Respiratory Protection: NIOSH-approved respirator if airborne exposure exceeds limits
Skin Protection: Chemical-resistant gloves (nitrile, neoprene), lab coat
Eye/Face Protection: Safety goggles or face shield
Hygiene Measures: Avoid eating, drinking, or smoking in work areas, wash hands after handling, launder contaminated clothing before reuse
Appearance: Off-white to pale yellow crystalline solid
Odor: None or mild aromatic
Melting Point: 214–218°C (literature)
Boiling Point: Data not available (decomposes)
Solubility: Soluble in organic solvents (ethanol, DMSO, chloroform); low water solubility
pH: Not determined
Flash Point: Data unavailable
Vapor Pressure: Negligible at room temperature
Density: Data not established
Stability: Stable at room temperature under recommended handling and storage
Viscosity: Not applicable
Chemical Stability: Stable under standard laboratory conditions, protects from excess moisture and air
Reaction Hazard: May react with strong oxidizers, acids, strong reducing agents
Conditions to Avoid: Excessive heat, flames, incompatible chemicals
Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon oxides
Polymerization: Does not occur under normal conditions
Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Oral toxicity reported in rodents; limited human data; estimated oral LD50 (rat) ~400 mg/kg
Skin Irritation: Causes mild to moderate irritation
Eye Irritation: Produces irritation, redness, discomfort
Sensitization: Data lacking
Chronic Effects: Experimental psychoactive/serotonergic toxicity in animals, possible impact on central nervous system
Other Effects: Animal studies suggest behavioral changes at high dose
Carcinogenicity: Not classified as a carcinogen
Mutagenicity: No data
Reproductive Effects: No adequate data available
Symptoms of Exposure: Nausea, dizziness, headache, agitation, skin redness
Environmental Fate: Not well studied; compounds may be persistent in water or soil
Aquatic Toxicity: Data not available; caution advised based on structural similarity to toxic phenylpiperazine derivatives
Bioaccumulation: Potential for bioaccumulation cannot be excluded
Soil Mobility: Not determined
Degradability: Unknown; studies lacking
Precautionary Measures: Prevent entry into waterways, soil, and drains
Waste Disposal: Use an approved hazardous chemical disposal facility, consider incineration under controlled conditions
Container Disposal: Triple rinse containers, dispose as hazardous waste
Environmental Precautions: Keep out of sewers, surface water, and groundwater systems
Legal Framework: Follow local, regional, and national hazardous chemical regulations
UN Number: Not assigned
UN Proper Shipping Name: Not regulated under most international transport regulations
Transport Hazard Class: None identified
Packing Group: Not established
Special Precautions: Use secure and labeled containers, prevent accidental release during transit, inform carrier of chemical risk
Regulations: Consider national and local limits for psychoactive substances, especially for international shipments
Inventory Status: Not listed under major chemical inventories (TSCA, EINECS, DSL)
Specific Legislation: Psychoactive compound, controlled in some jurisdictions under drug law or analogue regulations
Labeling Requirements: Hazard warning, toxicity notice, emergency response instruction
Workplace Use: Restricted to research with risk assessment and regulatory compliance in place
Other Restrictions: Limit handling by trained personnel, consider additional site-specific regulatory requirements
