Product Name: 1-Isopropylimidazole
Chemical Formula: C6H10N2
Synonyms: N-Isopropylimidazole, 2-Isopropyl-1H-imidazole
CAS Number: 3221-60-1
Recommended Use: Organic synthesis, chemical research
Supplier: Contact local chemical supplier or manufacturer directly
Emergency Contact: Chemtrec or regional poison control center
Manufacturer Address: Typically listed on the container or supplier documentation
GHS Classification: Acute Toxicity (Oral, Dermal, Inhalation, Eye and Skin Irritant)
Hazard Symbols: Exclamation mark
Signal Word: Warning
Hazard Statements: May cause skin and eye irritation, harmful if swallowed, can cause respiratory tract irritation
Precautionary Statements: Avoid contact with skin and eyes, do not breathe dust or vapor, wash exposed skin thoroughly after handling
Potential Health Effects: Headache, nausea, coughing, sore throat, redness or discomfort upon contact
Chemical Name: 1-Isopropylimidazole
CAS Number: 3221-60-1
Concentration: Approximately 98% or higher
Impurities: Trace level imidazole, water
Other Identifiers: EINECS: 221-498-1, Molecular Weight: 110.16 g/mol
Inhalation: Move exposed person to fresh air, keep at rest, seek medical attention if symptoms develop
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, medical care advised for persistent irritation
Eye Contact: Rinse eyes gently with clean water for 10–15 minutes, remove contact lenses if present, medical attention recommended
Ingestion: Rinse mouth with water, do not induce vomiting, get immediate medical help
Important Symptoms: Redness, tearing, burning sensation, difficulty breathing can occur after large exposures
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Specific Hazards: Vapors may form flammable mixtures with air, hazardous decomposition can release toxic nitrogen oxides
Protective Equipment: Full firefighting gear, self-contained breathing apparatus needed
Special Procedures: Avoid breathing smoke, use water spray to cool exposed containers, carry out fire response from a safe distance
Combustion Products: Nitrogen oxides, carbon monoxide, carbon dioxide, irritating fumes
Personal Precautions: Ventilate area, avoid breathing vapors, wear gloves, goggles and suitable protective clothing
Environmental Precautions: Prevent spillage into drains, watercourses, soil
Spill Cleanup: Absorb with inert material like sand or vermiculite, place in chemical waste container, wash spill site after material pickup
Notification: Inform safety personnel, dispose according to regulations
Safe Handling: Work in a fume hood, avoid inhalation and direct contact, wear chemical-resistant gloves, goggles, and lab coat
Incompatible Materials: Strong oxidizers, acids, acid chlorides
Storage Conditions: Keep tightly sealed, store in cool, dry, well-ventilated area, label containers clearly, keep away from heat and ignition sources
Recommended Storage Temperature: Room temperature or lower, protect from moisture
Container Requirements: Use sturdy, compatible containers with tight seals
Exposure Limits: No established occupational exposure limits for this compound
Engineering Controls: Use chemical fume hood, maintain good ventilation
Personal Protective Equipment: Chemical splash goggles, nitrile gloves, lab coat, use of a respirator if ventilation is poor
Hygiene Measures: Wash hands after use, remove contaminated clothing and wash before reuse
Environmental Controls: Prevent chemical runoff, use proper containment methods
Physical State: Colorless to pale yellow liquid
Odor: Slight, weakly amine-like
Melting Point: -33 °C
Boiling Point: 195–197 °C
Flash Point: 85 °C (closed cup, approximate)
Solubility: Mixes with water, soluble in alcohol and organic solvents
Density: Approximately 0.98 g/cm3 at 25°C
Vapor Pressure: Low at room temperature
pH: Around 10 (0.1 M solution)
Chemical Stability: Stable under normal use and storage, avoid exposure to excessive heat or light
Hazardous Reactions: Contact with strong acids releases heat, may react with oxidizers
Decomposition Products: Ammonia, oxides of carbon and nitrogen under extreme conditions
Conditions to Avoid: Open flames, spark sources, incompatible chemicals
Polymerization: Not known to occur
Acute Toxicity: Oral LD50 (rat) data not fully determined, based on imidazole analogs—mild to moderate toxicity possible
Skin Corrosion/Irritation: Irritating, possible redness and itch
Eye Damage/Irritation: Moderate eye irritant, causes redness, tearing
Respiratory Sensitization: Inhalation of vapor causes coughing, sore throat
Chronic Effects: No long-term studies, repeated contact might sensitize or irritate
Carcinogenicity/Mutagenicity: No data for 1-isopropylimidazole, related compounds generally not listed by OSHA, NTP, IARC
Symptoms: Headache, dizziness, skin or eye irritation after significant exposure
Ecotoxicity: Limited data, likely moderate aquatic toxicity based on related imidazoles
Persistence and Degradability: May degrade slowly in the environment, potentially persistent if released in large quantities
Bioaccumulation: Not expected to strongly bioaccumulate
Mobility in Soil: Expected to be mobile if spilled—readily dissolves in water, can leach into groundwater
Other Hazards: Avoid uncontrolled release to water or soil
Precaution: Always contain spills and follow best handling practices to minimize environmental impact
Waste Disposal Methods: Gather waste into sealed chemical containers, label and handle as hazardous waste, use licensed chemical waste disposal contractor
Contaminated Packaging: Rinse with water, dispose of as hazardous, avoid contact with incompatible materials
Legal Requirements: Comply with national, regional, and local statutes relating to waste chemical disposal
Recycling/Reuse: Not commonly recycled due to purity requirements, best option remains safe incineration if possible
UN Number: Not assigned
Proper Shipping Name: Chemical, N.O.S. (Not Otherwise Specified)
Hazard Class: Not classified as hazardous for transport
Packing Group: Not assigned
Transport Precautions: Keep tightly closed, protect from physical damage during transport, clearly mark containers
DOT/IATA/IMDG: Check for latest regulatory requirements; as of now, not specifically regulated
Special Provisions: Protect from moisture, store upright, separate from incompatible substances in transit
TSCA: Listed or requires notification
EINECS: 221-498-1
DSL/NDSL (Canada): Check supplier status
SARA Title III: Not listed as a reportable substance
REACH: Pre-registered or not specifically listed, registration may apply above 1 ton/year
Other Regulations: Not classified under major carcinogen, mutagen, or reproductive hazard lists, always refer to local or regional chemical control regulations for continued compliance
