Product Name: 1-Iodopyrrolidine-2,5-Dione
Chemical Formula: C4H4INO2
Synonyms: N-Iodosuccinimide
CAS Number: 516-12-1
Recommended Use: Laboratory reagent, oxidizing agent, halogenating agent
Supplier Details: Chemical suppliers or laboratory distributors; company-specific emergency contact available on product label
Emergency Contact Number: Refer to local poison control or company-specific line listed on packaging
GHS Classification: Oxidizing solid (Category 2), Acute toxicity oral (Category 4), Skin irritation (Category 2), Serious eye damage (Category 1)
Signal Word: Danger
Hazard Statements: May cause fire or explosion; strong oxidizer. Harmful if swallowed. Causes skin irritation. Causes serious eye damage.
Symbol: Flame over circle, exclamation mark, corrosion
Precautionary Statements: Keep away from heat, sparks, open flames. Wear protective gloves and eye protection. Do not eat, drink or smoke during use. Wash hands thoroughly after handling. Store in a dry place away from incompatible materials.
Chemical Name: 1-Iodopyrrolidine-2,5-Dione
Concentration: ≥ 98%
CAS Number: 516-12-1
Impurities/Additives: Trace materials may be present; check specific lot certificate of analysis for details
Mixture: Not a mixture; single chemical substance
Inhalation: Move person to fresh air. Seek medical attention if symptoms such as coughing or shortness of breath develop.
Skin Contact: Remove contaminated clothing. Wash affected area thoroughly with soap and water. Contact physician if irritation persists.
Eye Contact: Rinse with plenty of water for at least 15 minutes, lifting eyelids occasionally. Get immediate medical attention.
Ingestion: Rinse mouth with water. Do not induce vomiting. Seek medical help right away.
Most Important Symptoms: Irritation, redness, possible burns to skin or eyes. Harmful effects on ingestion include nausea.
Medical Attention: Physician should treat symptomatically and supportively.
Suitable Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or foam. Water spray can help cool containers.
Unsuitable Media: Avoid direct water jet on burning material.
Specific Hazards: May release toxic gases like iodine vapors, nitrogen oxides, carbon oxides under fire conditions. Strong oxidizer; intensifies fire.
Protective Equipment: Firefighters require self-contained breathing apparatus and full protective gear.
Advice for Firefighters: Evacuate area, prevent runoff from entering drains or waterways, and avoid inhaling combustion products. Cool unopened containers near fire with water spray.
Personal Precautions: Wear gloves, safety goggles, and appropriate lab coat or coveralls. Limit access to spill area. Avoid dust formation.
Environmental Precautions: Prevent further leakage or spillage. Do not allow material to enter drains, surface water, or soil.
Methods for Cleaning Up: Sweep up and place in suitable, labeled container for disposal. Wash spill site after material pickup is complete. Use non-sparking tools in spill areas.
Handling: Avoid inhalation, ingestion, and contact with skin or eyes. Wear personal protective equipment. Ensure good ventilation in work area. Keep away from incompatible substances like reducing agents or combustible materials.
Storage: Store in original container, tightly closed, in a cool, dry, and well-ventilated space, away from direct sunlight, heat sources, and moisture. Keep separate from acids, bases, and flammable materials. Do not store below 0°C or above 30°C for extended periods.
Engineering Controls: Work in a chemical fume hood or well-ventilated area. Install eyewash stations and emergency showers.
Personal Protective Equipment: Protective gloves (nitrile recommended), chemical splash goggles, lab coat, and respiratory protection if dust or fumes present.
Occupational Exposure Limits: No specific limits established for this compound; use general dust and chemical exposure guidelines.
Hygiene Measures: Always wash hands after handling and before breaks. Do not eat, drink, or smoke in work area. Remove contaminated clothing before leaving facility.
Appearance: White to off-white crystalline powder
Odor: Slight, characteristic
Odor Threshold: No data available
pH: No data available
Melting Point: 190–200°C
Boiling Point: Decomposes
Flash Point: No data available
Evaporation Rate: Not determined
Flammability: Not flammable, but may contribute to combustion
Vapor Pressure: No data available
Relative Density: No data available
Solubility: Soluble in water and organic solvents
Partition Coefficient (n-octanol/water): No data available
Viscosity: Not applicable
Decomposition Temperature: Above 200°C with toxic fumes
Reactivity: Strong oxidizer; reacts vigorously with reducing agents, active metals, and organic materials
Chemical Stability: Stable under recommended storage conditions
Possibility of Hazardous Reactions: Can react explosively with incompatible substances. May liberate iodine vapors.
Incompatible Materials: Acids, strong bases, reducing agents, combustible materials, powdered metals
Hazardous Decomposition Products: Iodine, nitrogen oxides, carbon oxides, and other toxic vapors on heating
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Acute Toxicity: Harmful by ingestion. May cause irritation to mucous membranes, skin, and eyes.
Skin Corrosion/Irritation: Causes skin irritation. Prolonged or repeated contact may result in dermatitis.
Serious Eye Damage/Irritation: Causes severe eye damage.
Respiratory or Skin Sensitization: Sensitization is not expected based on available data.
Chronic Effects: No long-term exposure data for this compound; repeated exposures may aggravate existing skin or eye conditions.
Carcinogenicity, Mutagenicity, Reproductive Effects: Not classified as carcinogen or mutagen; no reproductive toxicity data.
Aquatic Toxicity: Harmful to aquatic organisms; may cause long-term adverse effects in the aquatic environment.
Persistence and Degradability: Not readily biodegradable; decomposes slowly in nature, releasing iodine.
Bioaccumulative Potential: Not expected to bioaccumulate.
Mobility in Soil: May leach into soil and water systems.
Other Adverse Effects: Release to the environment should be avoided. Potential impact on microbial life in water or soil.
Waste Treatment Methods: Dispose through a licensed chemical waste disposal contractor. Dilute cautiously with water before disposal, following local and national regulations.
Contaminated Packaging: Triple rinse containers and offer for recycling or incineration through licensed facility.
Special Precautions: Do not dispose of into drains or environment. Avoid contact with other chemicals during disposal.
UN Number: 1479
UN Proper Shipping Name: Oxidizing solid, n.o.s. (1-Iodopyrrolidine-2,5-dione)
Transport Hazard Class: 5.1 (Oxidizing substances)
Packing Group: II
Marine Pollutant: Yes
Special Transport Precautions: Keep container upright and tightly sealed during transit. Ensure vehicle ventilation. Isolate from flammable materials and reducing agents.
US TSCA: Listed
EU REACH: Not listed as a registered substance
OSHA Hazards: Oxidizer, acute toxic, irritant
WHMIS Classification: Class C (Oxidizing material), Class D2B (Toxic material causing other effects)
SARA Title III Sec. 313: Not reported
California Proposition 65: Not known to contain substances listed
Chemical Inventory Status: Check local regulations; the status can change based on jurisdiction.
