Product Name: 1-Ethylpiperidin-3-ol
Chemical Family: Piperidine derivatives
Molecular Formula: C7H15NO
CAS Number: 69415-61-4
Synonyms: 1-Ethyl-3-hydroxypiperidine
Recommended Use: Laboratory chemicals, manufacturing intermediates
Supplier Details: Chemical Manufacturer Category, industrial supplier network, telephone support direct from safety officers, chemical orders helpline, street address available on invoice
Emergency Contact: Local Poison Control Center, regional chemical safety organization hotline, company-provided 24-hour number
Classification: Skin irritation, Category 2; Eye irritation, Category 2A; Acute toxicity (oral, dermal), Category 4
Signal Word: Warning
Hazard Statements: Causes skin irritation, serious eye irritation, may be harmful if swallowed or absorbed through skin, possible respiratory tract irritation following inhalation
Precautionary Statements: Wear suitable protective gloves and goggles, avoid breathing vapors, use only in well-ventilated areas, thoroughly wash after handling, avoid contact with eyes and skin
Iconography: Exclamation mark related to irritation risk, general health hazard pictogram indicating acute toxicity potential
Key Symptoms: Redness, pain or swelling of skin, watering and reddening of eyes, throat discomfort
Chemical: 1-Ethylpiperidin-3-ol
Concentration: Pure substance >98%
Impurities: Trace residual solvents below 0.1%, water content <0.5%
Formula Weight: 129.2 g/mol
Component Breakdown: No known additional hazardous ingredients present in mixtures for laboratory application
Regulatory Listings: Listed under chemical inventories according to regulations in regions such as EU REACH, US TSCA
Nature of Substance: Organic base, secondary amine group, alcohol functionality
General Notes: Move affected person from exposure area, keep at rest, obtain medical attention for any symptoms
Skin Contact: Promptly remove contaminated clothing, rinse affected skin thoroughly with soap and water for at least 15 minutes, monitor for persistent irritation, consult medical care if discomfort continues
Eye Contact: Immediately flush with plenty of lukewarm water for 15 minutes, hold eyelids apart, remove contact lenses if present and easy to do, seek medical care
Inhalation: Remove to fresh air, support breathing as needed, seek medical attention if respiratory symptoms develop
Ingestion: Rinse mouth, avoid induction of vomiting, give small amounts of water if person is conscious, get medical help promptly
Delayed Effects: Risk of eye damage, delayed skin reaction possible, respiratory discomfort could linger for several hours
Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam, water spray for cooling surfaces
Unsuitable Media: Avoid direct water jet as chemical runoff may spread contamination
Fire Hazards: Vapors can form explosive mixtures with air at higher temperatures, decomposition releases toxic fumes such as nitrogen oxides, carbon oxides, small amounts of amines
Protective Equipment: Full protective gear and self-contained breathing apparatus for fire crews, chemical-resistant gloves, boots, face shields
Additional Notes: Containers may burst from pressure buildup under fire conditions, water runoff risk for environmental contamination, discarding all soiled materials in accordance with local regulations after firefighting
Personal Protection: Don chemical splash goggles, gloves, impervious apron, ensure adequate ventilation, evacuate unnecessary personnel
Spill Response: Absorb liquid with inert material like sand or vermiculite, transfer to appropriate waste containers with chemical label
Cleanup Methods: Use non-sparking tools, ventilate area, mop residues with a solution of mild detergent followed by abundant water, avoid combustible absorbents
Environmental Precaution: Prevent spillage from reaching sewers or natural water sources, block drains, consult environmental officer for cleanup protocols
Disposal Guidance: Collected waste classified as hazardous, label accordingly, transport via licensed waste contractor, maintain spill log for tracking and future audits
Safe Handling: Perform handling in chemical fume hood or engineered ventilated area, use closed containers, wash hands thoroughly after manipulation, minimize skin and eye contact by disciplined work habits
Storage Requirements: Keep in cool, well-ventilated area, moisture-sensitive packaging, avoid sources of heat and strong oxidizers, segregate from incompatible substances such as acids or strong alkalis
Storage Conditions: Use containers compatible with amines and alcohols, label all containers with date and lot number, keep tightly sealed when not in use
Fire Hazard Precaution: No smoking near storage sites, ground and bond transfer equipment, maintain access to chemical spill kits and eyewash stations
Incompatibilities: Acidic materials, anhydrides, strong oxidizers, reducing agents
Occupational Exposure Limits: No established specific limits; follow general exposure values for amine alcohols, often 1–5 ppm for reference
Engineering Controls: Utilize chemical fume hoods, exhaust fans, protective enclosures, ensure continuous air monitoring if working in enclosed environment
Respiratory Protection: Wear approved organic vapor respirators for operations outside of hood or during spill response
Skin Protection: Impervious gloves such as nitrile, long-sleeved lab coats, chemical boots
Eye and Face Protection: Tight-fitting goggles, full-face shield for high-risk procedures, eyewash within 10 meters of work station
Other Protection: Wash facilities at access points, routine laundering of work clothes, spill-ready PPE stored nearby
Exposure Monitoring: Regular personal air monitoring for extended projects, biological sampling at medical surveillance intervals depending on use scenario
Appearance: Colorless to pale yellow, clear liquid, no visible particulates, flows freely at room temperature
Odor: Mild, amine-like with faint alcohol undertone
Odor Threshold: Not established; low-level detection for trained staff
pH: Approx 11 (typical for secondary amine alcohol), measurable in dilute aqueous solution
Melting Point: - Not determined, remains liquid at standard room temperature
Boiling Point: Estimated around 198–205°C based on molecular structure
Flash Point: Approximately 91°C (closed cup method)
Evaporation Rate: Slow at ambient conditions, faster with air flow
Flammability: Combustible liquid, not highly flammable but presents burning risk
Vapor Pressure: Low at 20°C (approx 1–2 mmHg)
Vapor Density: Heavier than air
Solubility: Miscible with water and most polar organic solvents
Partition Coefficient (octanol/water): Estimated log Pow < 1, indicating low potential for bioaccumulation
Decomposition Temperature: Not fully characterized, likely above 210°C
Viscosity: Not high, near that of water, facilitates easy pouring
Chemical Stability: Stable under normal laboratory and storage conditions if moisture and oxidizing agents are excluded
Condition to Avoid: Strong heat, direct sunlight, prolonged contact with acids, oxidizers, high humidity
Reactive Hazards: Violent reaction possible with strong oxidizing agents or formation of toxic nitrogen oxides under combustion
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, minor amines and aldehydes can form during over-heating
Polymerization: No information on self-polymerization; low risk based on chemical structure
Storage Incompatibles: Acid chlorides, anhydrides, chloroformates, strong mineral acids
Other notes: Avoid contamination by metals or moisture, secure airtight seal on secondary containment
Routes of Exposure: Inhalation, ingestion, eye and skin contact
Acute Toxicity: LD50 (oral, rat): 320–375 mg/kg (literature-based range for similar structures), LD50 (dermal, rabbit): >1000 mg/kg
Skin Irritation: Causes moderate inflammation, reversible on removal of contaminated clothing
Eye Irritation: Produces marked discomfort, tearing, redness, reversible with prompt irrigation
Respiratory Effects: Vapor inhalation can cause sore throat, coughing, mild bronchial irritation on sustained exposure
Chronic Effects: No long-term animal studies published, no known mutagenicity or carcinogenicity reports, monitor for potential delayed hypersensitivity in frequent users
Target Organs: Respiratory tract, skin, eyes
Additional Data: Chemical structure supports potential for secondary amine-related irritation, standardized tox screens recommended for new applications
Environmental Toxicity: Predicted moderate aquatic toxicity to invertebrates and fish, based on similar piperidine derivatives; LC50 (fish, 96hr): estimated 50–200 mg/L
Persistence and Degradability: Readily biodegradable over a period of weeks under aerobic soil and activated sludge conditions
Bioaccumulation: Low risk as log Pow below 1.0, rapid metabolism expected in environmental compartments
Mobility in Soil: High mobility due to water solubility, may leach into water tables with improper disposal
Additional Concerns: Avoid large-scale releases, report spills to regulatory agencies if environmental thresholds exceeded, establish secondary containment near drains in workspaces
Waste Treatment Methods: Incinerate under controlled conditions at licensed facility, package material in labeled chemical waste drums
Disposal of Contaminated Packaging: Rinse with copious water, dispose as hazardous lab waste, do not reuse or recycle chemically exposed containers
Environmental Release Prevention: Use absorbents for remnants, ensure all labs are equipped with liquid-tight chemical bins
Local Regulations: Follow all applicable regulations, consult municipal and national waste codes, log waste movement in hazardous inventory
Other Options: Neutralization under supervision by professional chemical waste handlers
UN Number: Not assigned for small/research quantities; consider UN2810 for toxic liquids, organic, n.o.s. for bulk shipment
Proper Shipping Name: 1-Ethylpiperidin-3-ol, flammable liquid, amine-alcohol
Hazard Class: 6.1 (toxic), 3 (flammable liquid auxiliary) as applicable
Packing Group: III (minor hazard), require leakproof sealed containers
Transport Labels: "Toxic", "Flammable Liquid" as determined by amount and concentration
Special Precautions for User: Vehicle ventilation crucial, keep away from heat and open flames, properly secure containers to avoid leaks or shifting in transit
Marine/International Codes: Comply with IMDG, IATA requirements, provide transport documentation and emergency contact sheets
Inventory Status: Listed on major international and regional chemical inventories such as TSCA (US), DSL (Canada), REACH (EU); annual reporting required for certain thresholds
Workplace Regulation: Subject to Occupational Safety and Health (OSH) hazard communication rules, includes right-to-know and labeling standards
Hazardous Chemical Category: Classified for workplace physical/health hazard under local codes, risk of regular workplace inspections
Environmental Release Limits: Not covered under specific priority pollutant releases, but included in general "new chemical substances" guidelines
Labelling Requirements: Complete hazard icons, risk and safety phrases, supplier identification on primary and secondary containers
Training Obligations: Workers must be trained in chemical hazards, emergency procedures and use of PPE before handling
Community Right-to-Know: Notification duties exist for bulk storage or release scenarios; consult with regional environmental regulatory bodies for updates
