Chemical Name: 1-Ethyl-2-(Nitromethylene)Pyrrolidine
Synonyms: N-Ethyl-2-(nitromethylene)pyrrolidine
Chemical Formula: C7H12N2O2
CAS Number: 26452-81-5
Use of Substance: Organic synthesis intermediate, research chemical
Manufacturer/Supplier: Contact supplier for latest information
Emergency Contact Number: Listed by individual suppliers
Globally Harmonized System Classification: Acute toxicity (oral and inhalation), Eye irritation, Skin irritation, Specific target organ toxicity
Label Elements: Warning, Skull and crossbones, Exclamation mark
Hazard Statements: Harmful if swallowed or inhaled, causes serious eye irritation, may cause respiratory irritation
Precautionary Statements: Avoid breathing dust or vapors, wash hands thoroughly after handling, use only outdoors or in a well-ventilated area, wear protective gloves, protective clothing, and eye/face protection
Potential Health Effects: Short-term exposure brings nausea, headache, respiratory discomfort, clouded vision, prolonged skin contact leads to redness or dryness
Environmental Hazards: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Main Ingredient: 1-Ethyl-2-(Nitromethylene)Pyrrolidine
Concentration: 97-99% pure (as provided by suppliers)
Impurities: Water (≤ 2%), minor side products from synthesis
Additives: None included
Other Components: Not applicable for this compound
Inhalation: Remove individual to fresh air, keep comfortable for breathing, seek medical attention for persistent discomfort or dizziness, provide artificial respiration if breathing stops
Skin Contact: Remove contaminated clothing, wash affected area with soapy water for at least 15 minutes, seek medical advice for irritation or symptoms
Eye Contact: Flush open eye with gentle stream of water for a minimum of 15 minutes, remove contact lenses, immediate medical assistance is needed
Ingestion: Rinse mouth, drink water in small sips, avoid inducing vomiting, consult medical staff urgently
Most Important Symptoms: Coughing, breathing difficulties, redness, rash, stomach pain, headache, potential chemical burns on sensitive tissue
Notes for Physician: Treat symptomatically, monitor for delayed symptoms, provide supportive care
Suitable Extinguishing Media: Foam, carbon dioxide, dry chemical powder, avoid water jets if possible
Specific Hazards: Toxic gases like nitrogen oxides and carbon monoxide may be released on combustion, potential for thermal decomposition products
Fire-Fighter Protection: Firefighters should use full turn-out gear and self-contained breathing apparatus
Advice on Extinguishing: Cool containers with lots of water, move containers from danger zone if safe, block product leaks with sand or earth, wash down spills with excess water only after complete cool down
Personal Precautions: Wear chemical resistant gloves, goggles, and protective clothing, avoid dust generation, use ventilation
Environmental Precautions: Prevent product from entering surface water, soil, or storm drains, do not allow chemical into sewers
Containment: Scoop up and collect spilled material in a dry, inert, chemical waste container for disposal
Cleanup Methods: Neutralize with chemical deactivators approved for nitro compounds, use absorbent materials like sand or vermiculite, wash area with copious amounts of water after collection
Decontamination Recommendations: Wash tools and contaminated equipment thoroughly before reuse
Precautions for Safe Handling: Ventilate work areas, avoid static discharge, handle away from food and drink, minimize skin and eye contact, open containers carefully using appropriate PPE
Storage Requirements: Store in tightly closed original container, away from sunlight, heat sources, oxidizers, acids, and bases, maintain temperature between 2-8°C, keep dry
Incompatibilities: Strong acids, strong bases, reducing agents, oxidizing agents
Other Information: Label containers with appropriate hazard warnings, restrict access to trained personnel only, implement inventory management controls
Exposure Limits: No government occupational exposure limits established, handle with engineering controls
Engineering Controls: Use chemical fume hood or local exhaust ventilation, control dust and vapor emissions, use explosion-proof equipment in case of volatile batches
Respiratory Protection: Use NIOSH-approved respirators if exposure risk remains
Eye Protection: Chemical splash goggles compliant with ANSI Z87.1
Skin Protection: Chemical-resistant gloves (nitrile, neoprene), lab coat, long pants, closed shoes, no open skin
Hygiene Measures: Wash hands and face thoroughly after handling, do not eat or drink at worksite, clean contaminated clothing before reuse
Appearance: Pale yellow to amber oily liquid
Odor: Lightly pungent, similar to organic nitro compounds
Odor Threshold: Not determined
pH: Not applicable (neat)
Melting Point: -24°C (estimated)
Boiling Point: 218-221°C at 1 atm
Flash Point: Approximately 99°C (closed cup)
Evaporation Rate: Slow; less than water
Flammability: Not highly flammable but supports combustion
Explosion Limits: Not established
Vapor Pressure: Estimated below 0.1 mmHg at 20°C
Vapor Density: Heavier than air
Relative Density: 1.21 g/cm³
Solubility: Slightly soluble in water; mixes well with acetone, ethanol, organic solvents
Partition Coefficient: Not determined
Autoignition Temperature: Not established
Decomposition Temperature: Slight decomposition above 160°C
Viscosity: Medium, similar to light oil at room temperature
Chemical Stability: Stable for extended periods below room temperature, unstable at high temperatures, avoid direct sunlight
Reactivity: Reacts violently with strong oxidizers, acids, strong reducing agents
Hazardous Decomposition: Nitrogen oxides, carbon monoxide, toxic vapors released during burning or thermal decomposition
Polymerization: Does not undergo hazardous polymerization
Other Comments: Shelf life varies depending on purity and storage, impurities may accelerate decomposition
Likely Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Oral LD50 (rats) estimated between 250-500 mg/kg, inhalation LC50 (rats) estimated 250-500 ppm/4h, skin LD50 (rats) not determined
Symptoms: Abdominal cramps, respiratory distress, headache, vomiting, skin and eye irritation, possible dizziness
Chronic Exposure: Prolonged exposure linked to decreased liver function, CNS depression, dermatitis in repeated contact
Sensitization: Not known to cause sensitization, vigilance necessary for allergic response
Carcinogenicity: Not classified as a human carcinogen by ACGIH, IARC, OSHA, NTP
Mutagenicity: No mutagenicity in Ames test, no reproductive toxicity evidence
Other Data: Not a known reproductive hazard, but has not undergone full chronic toxicity screening
Ecotoxicity: Highly toxic to aquatic life, LC50 (fish, 96h): estimated 2-5 mg/L, EC50 (daphnia, 48h): 1-2 mg/L
Persistence and Degradability: Readily biodegradable in soil and water but may persist if large volumes are released
Bioaccumulative Potential: Low potential due to rapid biotransformation, log Kow not determined
Mobility in Soil: Moderate, leaching risk in sandy soils
Other Harmful Effects: Harmful to aquatic plants and amphibian embryos, disrupts algal reproduction in low concentrations
Disposal Methods: Incinerate in a chemical incinerator with afterburner and scrubber, follow all local and national regulations, avoid disposal in natural waterways
Contaminated Packaging: Rinse containers with a suitable solvent, dispose in accordance with chemical waste regulations, label as hazardous
Precautions for Disposal: Use personal protection, prevent spills, maintain full records for waste shipment
UN Number: 2810 (Toxic Liquid, Organic, N.O.S.)
Class: 6.1 (Toxic substances)
Packing Group: III
Proper Shipping Name: Toxic Liquid, Organic, N.O.S. (Contains 1-Ethyl-2-(Nitromethylene)Pyrrolidine)
Transport Hazard: Toxic by ingestion or inhalation
Special Precautions: Use leak-proof packaging, mark all containers with a poison hazard statement, prohibit shipment with foodstuffs or animal feeds
Labeling as per OSHA HCS: Regulated as hazardous, subject to Safety Data Sheet requirements
TSCA Status: Check supplier, not guaranteed to be listed
REACH Status (EU): May require registration for import and handling, contact authority for substance-specific annex data
SARA 313: Subject to reporting when handled in large quantities
WHMIS (Canada): Class D1B (Toxic Material), Class E (Corrosive Material); workplace-specific controls apply
Other Regulations: Not regulated as an explosive or narcotic, export and use controls may exist depending on local laws
