Material Safety Data Sheet - 1-Cyclohexyl-1H-Pyrrole-2,5-Dione

Identification

Chemical Name: 1-Cyclohexyl-1H-Pyrrole-2,5-Dione
Synonyms: N-Cyclohexyl Maleimide, Cyclohexylmaleimide
CAS Number: 3886-69-9
Recommended Use: Chemical intermediate, cross-linking agent, specialty chemicals formulation
Supplier: Commercial chemical distributor or manufacturer
Contact Information: Safety officer or technical support line provided by supplier
Emergency Contact: Regional emergency number such as CHEMTREC or local poison control

Hazard Identification

Classification: Irritant, possible skin sensitizer, not classified as a carcinogen based on available data
GHS Label Elements: Exclamation mark symbol
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation. May cause an allergic skin reaction. Harmful if swallowed.
Precautionary Statements: Avoid breathing dust or vapor, wear protective gloves and eye protection, wash hands thoroughly after handling
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Physical State: Solid or powder, white to beige appearance, slight odor

Composition / Information on Ingredients

Chemical Identity: 1-Cyclohexyl-1H-Pyrrole-2,5-Dione
Common Name: N-Cyclohexyl Maleimide
Concentration: 97–99%
Impurities: Trace levels of related maleimide derivatives and solvents, typically less than 1%
Additives: None intentionally added

First Aid Measures

Inhalation: Move person to fresh air, get medical attention if symptoms persist such as coughing or shortness of breath
Skin Contact: Remove contaminated clothing, wash exposed skin with plenty of water and mild soap, seek medical care if irritation develops
Eye Contact: Rinse opened eye under running water for several minutes, lift eyelids to ensure thorough rinsing, consult eye specialist if discomfort or irritation lingers
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical attention
Most Important Symptoms: Redness, itching, rash, respiratory irritation or discomfort

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical powder, foam, carbon dioxide, water spray (avoid jets that may spread powder)
Unsuitable Media: Direct water streams
Hazards from Combustion: Emission of carbon oxides, nitrogen oxides, possible formation of toxic smoke
Special Protective Equipment: Full protective clothing and self-contained breathing apparatus
Firefighting Instructions: Keep containers cool by spraying with water, prevent firefighting runoff from entering waterways
Explosion Data: Non-explosive under normal storage and handling conditions

Accidental Release Measures

Personal Precautions: Evacuate area if dust levels increase, ventilate area, wear adequate personal protective equipment (respirator, gloves, goggles)
Environmental Precautions: Do not allow product to reach drains, waterways, or soil
Spill Cleanup: Sweep or scoop solid product into containers for disposal, use damp cloths to reduce dust generation, wash area with water after waste removal
Special Procedures: Dispose of cleaning materials in accordance with local regulations

Handling and Storage

Handling: Use within fume hoods or well-ventilated areas, avoid generating dust, keep away from strong oxidizers, follow normal chemical hygiene practices
Storage: Keep in tightly sealed, labeled containers, store in cool, dry, well-ventilated place, away from direct sunlight and incompatible substances
Storage Class: Chemical storage group for solids, may be grouped with organic peroxides or sensitizers
Incompatibilities: Strong acids, strong bases, oxidizing agents

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific OSHA, NIOSH, or ACGIH limits established, maintain airborne concentrations as low as reasonably achievable
Engineering Controls: Local exhaust ventilation recommended, safety showers and eyewash stations accessible
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), safety goggles with side protection, lab coat or coveralls, particulate respirator if dust might occur
Hygiene Measures: Wash hands before eating or drinking, remove contaminated clothing before leaving work area, do not eat or drink while handling product

Physical and Chemical Properties

Appearance: White or off-white crystalline powder
Odor: Mild, not distinctive
Odor Threshold: Not established
pH: Not applicable (insoluble in water)
Melting Point: 100–105°C (approximately)
Boiling Point: Not easily determined; decomposition may occur before boiling
Flash Point: Over 200°C (closed cup)
Flammability: Not readily flammable as solid
Vapor Pressure: Negligible at room temperature
Solubility: Poorly soluble in water, soluble in organics such as acetone and ethanol
Density: ~1.2 g/cm³
Partition Coefficient: Log Kow unavailable
Decomposition Temperature: >130°C
Viscosity: Not applicable
Molecular Weight: 179.22 g/mol

Stability and Reactivity

Chemical Stability: Stable under standard storage and handling conditions
Reactivity: May react with strong oxidizers, can undergo polymerization in presence of bases
Hazardous Reactions: No hazardous polymerization expected under normal use
Conditions to Avoid: Extreme heat, exposure to light, contact with acids or bases
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, smoke when burned

Toxicological Information

Acute Toxicity (Oral): Low oral toxicity based on analogs, LD50 in rat estimated >2,000 mg/kg
Skin Corrosion/Irritation: Causes skin irritation, redness, possible sensitization in repeated exposures
Serious Eye Damage/Irritation: Causes irritation, tearing, conjunctivitis
Respiratory or Skin Sensitization: Skin sensitizer in animal or human data reported
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, OSHA
Mutagenicity: Not classified as mutagenic based on available studies
Repeated Dose Toxicity: Not fully characterized; long-term exposure should be limited due to potential skin or respiratory sensitization

Ecological Information

Aquatic Toxicity: Data limited, likely harmful to aquatic life with long lasting effects
Persistence and Degradability: Not readily biodegradable under environmental conditions
Bioaccumulation Potential: Low to moderate potential, monitoring advised
Mobility in Soil: Expected to have low mobility, limited water solubility
Other Adverse Effects: Avoid release to environment, proper waste treatment critical

Disposal Considerations

Waste Methods: Handle as hazardous chemical waste. Dispose at licensed hazardous waste facility.
Container Disposal: Empty containers cleaned with solvent and water, dispose according to local regulations.
Recommended Disposal: Incineration by permitted facility is preferred if recycling or disposal by other methods not possible.
Regulatory Requirements: Follow requirements of local, regional, and national authorities.

Transport Information

UN Number: Not assigned
Shipping Name: Not regulated for transport under typical conditions
Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: Not classified but avoid aquatic release
Special Transport Precautions: Keep container tightly sealed, transport in upright position, ensure secondary containment to prevent spills

Regulatory Information

TSCA Status: Listed on the Toxic Substances Control Act (TSCA) inventory
REACH Status: Not registered for European Union market by all suppliers; consult supplier for updated information
SARA Title III: Not subject to reporting requirements under SARA 302, 304, 313
California Proposition 65: No known listing
Other Regulations: Review all applicable international, federal, state, and local regulations related to health and safety before use
Labelling Requirements: GHS-compliant labeling recommended for all handling and shipping