Material Safety Data Sheet for 1-Chloroformyl-4-Piperidinylpiperidine

1. Identification

Product Name: 1-Chloroformyl-4-Piperidinylpiperidine
Chemical Formula: C10H17ClN2O
Other Names: N-(4-Piperidinyl)piperidine-1-carbonyl chloride
CAS Number: [Check local registry databases]
Intended Use: Intermediate for synthesis in chemical research and industrial labs
Manufacturer: [List your company and address]
Emergency Contact: [Insert local poison control center and company emergency line]

2. Hazard Identification

Classification: Acute toxicity (oral, inhalation, skin), skin corrosion or irritation, serious eye damage
Signal Word: Danger
Hazard Symbols: GHS05 (corrosive), GHS06 (toxic)
Hazard Statements: Causes severe burns and eye damage, harmful if inhaled, toxic in contact with skin, toxic if swallowed
Precautionary Statements: Avoid breathing dust, vapors, spray; wash hands thoroughly after handling; use only outdoors or in a well-ventilated area; wear impervious gloves, protective clothing, and eye protection
Physical Hazards: Corrosive to metals; reacts with water forming toxic fumes
Health Hazards: Inhalation can cause coughing, respiratory tract irritation, shortness of breath; skin contact leads to corrosion, burning sensations, possible blistering; eye exposure brings on pain, redness, blindness risk
Environmental Hazards: Can damage aquatic life; runoff may pollute waterways

3. Composition / Information on Ingredients

Chemical Name: 1-Chloroformyl-4-Piperidinylpiperidine
Concentration: 97–100%
Impurities: Residual piperidine derivatives, solvents (trace amounts)
Molecular Weight: 216.71 g/mol
Structure: [Provide structural formula or SMILES as reference in laboratory portal]

4. First Aid Measures

Inhalation: Move person to fresh air immediately, loosen tight clothing, provide oxygen or artificial respiration if necessary, seek medical attention without delay
Skin Contact: Remove contaminated clothes, wash skin with copious amounts of running water and mild soap, seek medical help for persistent irritation or burns
Eye Contact: Rinse eyes for at least 15 minutes under running water, lifting both upper and lower eyelids frequently, remove contact lenses if present and easy to do, get emergency medical support
Ingestion: Rinse mouth with water (do not induce vomiting), keep person at rest, seek hospital care right away, note substance and dosage

5. Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide; avoid water jet, which might cause reaction
Specific Hazards: Releases toxic gases such as hydrogen chloride, nitrogen oxides, carbon monoxide under heat or fire conditions
Advice for Firefighters: Wear self-contained breathing apparatus and fully encased protective gear
Firefighting Methods: Stay upwind, use water spray to keep fire-exposed containers cool, evacuate personnel from danger zone, contain runoff for proper disposal

6. Accidental Release Measures

Personal Precautions: Evacuate area; ventilate space; put on chemical-resistant gloves, full face shield, aprons, and boots
Environmental Measures: Prevent spill from entering drains, watercourses; contain with sand or earth; use vapor suppressing foam for large spills
Cleanup Method: Absorb with inert material such as diatomaceous earth, collect in non-metallic container with tight lid, clean area with plenty of water, ventilate thoroughly
Cautions: Immediately place soaked materials in containers for disposal, never touch spilled product bare handed, avoid inhaling vapor

7. Handling and Storage

Handling: Handle under chemical fume hood or in well-ventilated space, avoid skin and eye contact, wear splash goggles and impervious gloves, access shower and eyewash station nearby, never pipette by mouth
Storage: Store in tightly sealed chemical-resistant containers, away from moisture, oxidizing agents, acids, and bases, at temperatures below 25°C; label all storage vessels; monitor temperature and humidity
Incompatibilities: Water, strong oxidizers, bases, strong acids
Bulk Storage Considerations: Keep in area dedicated for hazardous materials, use corrosion-resistant shelving

8. Exposure Controls and Personal Protection

Permissible Exposure Limits: Not established (check agency listings for updates)
Engineering Controls: Fume hoods, adequate room ventilation, closed systems
Personal Protective Equipment: Chemical splash goggles, face shield, gloves (nitrile or neoprene), long chemical-resistant apron, full body suit for high-exposure risk
Hygiene Measures: Wash hands, face, and forearms thoroughly before breaks and at day’s end; do not eat or drink in the lab; remove soiled clothing promptly; keep work area clean

9. Physical and Chemical Properties

Appearance: Colorless to pale yellow solid or liquid (depending on storage conditions)
Odor: Pungent, amine/chlorinated odor
Melting Point: 35–39°C
Boiling Point: Est. 290–305°C
Solubility: Decomposes in water, soluble in organic solvents such as dichloromethane, chloroform, acetonitrile
Vapor Pressure: Low at room temperature
Relative Density: Approx. 1.12–1.16 g/cm³
pH: Highly acidic if dissolved in water
Flash Point: Not precisely established, presumed high
Partition Coefficient (log Pow): Not confirmed, estimated moderate hydrophobicity
Auto-ignition Temperature: Not available

10. Stability and Reactivity

Chemical Stability: Stable in sealed containers under dry, cool conditions
Reactivity: Decomposes in contact with water; forms corrosive and toxic fumes; very reactive with alkalis, strong acids, oxidizers
Conditions to Avoid: Humidity, elevated temperatures, sunlight, sources of ignition
Hazardous Decomposition Products: Hydrogen chloride gas, carbon monoxide, carbon dioxide, nitrogen oxides
Polymerization: Not prone to hazardous polymerization but keep away from reactive chemicals to avoid uncontrolled reactions

11. Toxicological Information

Acute Toxicity: Ingestion or inhalation even at low amount causes nausea, vomiting, severe irritation, central nervous system effects, headache, dizziness, and may be fatal
Skin Corrosion/Irritation: Causes burns, pain, and possible necrosis at site of contact
Serious Eye Damage: Corrosive, risk of blindness if splashed
Respiratory Sensitization: Breathing vapor or dust brings on persistent cough, burning in airways, risk of pulmonary edema
Chronic Toxicity: Repeat exposure might lead to organ damage, especially liver and kidneys
Carcinogenicity: Not classified as carcinogen by major agencies but data’s limited
Mutagenicity: Not well studied; use utmost caution
Reproductive Hazards: No definite data, keep pregnant women away from exposure

12. Ecological Information

Ecotoxicity: Toxic to aquatic organisms, causes long-term adverse effects in aquatic environments
Persistence and Degradability: Degrades slowly; breakdown products toxic to life forms
Mobility: Bound to soil in spills; possible migration to groundwater
Bioaccumulation: No detailed data, but structurally similar compounds build up in organisms
Other Adverse Effects: Spillage could harm microorganisms, plants, and disrupt ecosystem balance; always contain waste
Precautions: Avoid direct contact with natural environments; keep all waste and residues contained until processed

13. Disposal Considerations

Waste Disposal: Treat as hazardous chemical waste—incinerate in controlled facility licensed for chlorinated organics, or coordinate with hazardous waste processors
Container Disposal: Triple rinse with suitable solvent, puncture, and tag for hazardous waste disposal
Environmental Precautions: Do not allow any product, residue, or rinse waters to reach sewer, surface water, or soil
Regulations: Meet local, national, and international waste handling standards for industrial chemicals

14. Transport Information

UN Number: [Consult latest UN lists for correct assignment]
Proper Shipping Name: 1-Chloroformyl-4-Piperidinylpiperidine, or Organic chloride, liquid, corrosive
Transport Hazard Class: 8 (Corrosive), with Toxic subsidiary risk
Packing Group: II or I (depending on purity and volume)
Label Requirements: Corrosive, Toxic, Environmental Hazard labels required
Additional Precautions: Ship in tightly sealed drums, use secondary containment, notify carriers of reactive and corrosive risks
Special Transport Notes: Avoid transporting with food, feed, or incompatible chemicals; always have emergency spill protocol ready

15. Regulatory Information

TSCA Status: Check with EPA for stateside registration
REACh Status: Registration or notification required; check status on ECHA portal
Workplace Classification: Listed hazardous substance under OSHA Hazard Communication Standard
Labeling: GHS-compliant pictograms, hazard statement codes, precautionary statements on every container
Other Laws: Subject to chemical control inventories in most jurisdictions; may need reporting for shipments across state or national boundaries