Product Name: 1-Butylpyrrolidin-2-One
Synonyms: N-Butyl-2-pyrrolidone, Butylpyrrolidone, NBP
CAS No.: 3470-98-2
Recommended Uses: Used as solvent in pharmaceuticals, agricultural chemicals, electronics, and cleaning agents
Supplier Identification: Manufacturer’s name, address, and 24-hour emergency contact number required on the label
Emergency Phone: Local poison information center or emergency numbers as applicable
Product Code: Specific code provided by supplier or manufacturer for tracing batches
Classification: Eye irritation category 2, Skin irritation category 2, Reproductive toxicity category 2, Acute toxicity category 4 (oral and dermal)
Hazard Statements: Causes serious eye irritation, may cause skin irritation, suspected of damaging fertility or the unborn child, harmful if swallowed or absorbed through skin
Pictograms: Exclamation mark, Health hazard
Signal Word: Warning
Precautionary Statements: Avoid breathing vapors or mist, wear protective gloves, rinse eyes cautiously, wash hands thoroughly, seek medical attention if exposed or if feeling unwell
C hemical Name: 1-Butylpyrrolidin-2-One
CAS Number: 3470-98-2
EC Number: 222-439-0
P urity: 98% or higher
Impurities/ Additives: Trace amounts may include residual solvents or by-products below threshold for hazard classification
Exposure Limits: No established occupational exposure limits, handle as hazardous based on potential effects
Eye Contact: Immediately flush with water for at least fifteen minutes, holding eyelids open, seek medical advice
Skin Contact: Remove contaminated clothing, rinse affected area with water and soap, consult a physician if irritation or symptoms develop
Inhalation: Move person to fresh air, assist breathing if necessary, seek medical attention if any symptoms develop
Ingestion: Rinse mouth, do not induce vomiting, provide water if victim is conscious, seek immediate medical advice or attention
Acute Symptoms/Effects: May include irritation, headache, nausea, or drowsiness
Delayed Symptoms: Prolonged or repeated skin exposure may cause dermatitis; chronic exposure could affect liver or kidney function based on animal studies
Suitable Extinguishing Media: Alcohol-resistant foam, water spray, dry chemical powder, carbon dioxide
Unsuitable Extinguishing Media: Direct water jet may spread liquid
Hazardous Combustion Products: Carbon oxides (CO, CO₂), nitrogen oxides
Specific Hazards: Vapors may form explosive mixtures with air above flash point in closed spaces
Protective Equipment: Firefighters use self-contained breathing apparatus and protective gear against toxic combustion gases
Special Procedures: Use water spray to cool containers exposed to fire, avoid runoff from fire control entering waterways
Personal Precautions: Use personal protective equipment such as gloves, goggles, and chemical-resistant clothing
Evacuation: Evacuate unprotected personnel from area of large spills, ventilate the area
Environmental Precautions: Prevent entry into waterways, drains, or soil; contain and stop leak if safe to do so
Cleanup Methods: Absorb spill with inert material (sand, earth), collect for disposal in suitable container, wash spill area with water after removal
Disposal: Handle as hazardous waste according to local, state, and national regulations; consult with waste disposal experts
Safe Handling: Use only in well-ventilated areas, avoid inhaling vapors and contact with skin or eyes, keep container tightly closed when not in use
Storage Conditions: Store in cool, dry conditions, away from heat, sunlight, direct ignition sources, incompatible materials (strong oxidizers, acids)
Storage Class: Chemical storage for organic solvents, segregated from food, feed, and incompatible substances
Special Requirements: Ground containers when transferring to prevent static discharge, keep away from open flames and sparks
Container Materials: Use containers made of compatible materials such as polyethylene or stainless steel, check integrity regularly
Engineering Controls: Use with adequate ventilation or local exhaust to minimize airborne concentrations, laboratory fume hood recommended for small-scale handling
Personal Protection: Wear chemical-resistant gloves (nitrile, neoprene), safety goggles or face shield, protective clothing, impervious boots in large spills
Respiratory Protection: Use approved respirator if exposure limit values are exceeded or during emergency spill response
Hygiene Measures: Wash hands after handling, do not eat, drink, or smoke in areas where chemical is used, remove contaminated clothing before entering clean areas
Monitoring: Regular workplace monitoring for airborne concentrations if used in volume or regularly handled
Appearance: Clear, colorless to light yellow liquid
Odor: Faint, amine-like
Odor Threshold: Not available
pH: Neutral (approximate in water)
Melting Point: -75°C
Boiling Point: 244°C
Flash Point: 122°C (closed cup)
Evaporation Rate: Slow relative to other solvents
Upper/Lower Flammability Limits: Not determined
Vapor Pressure: ~0.03 mmHg at 25°C
Vapor Density: 5.2 (air = 1)
Relative Density: 0.982 g/cm³ at 25°C
Solubility (Water): Miscible
Partition Coefficient (n-octanol/water): Not established
Decomposition Temperature: Not determined
Viscosity: 2.03 cP at 20°C
C hemical Stability: Stable under recommended storage and handling conditions
Reactivity: Generally unreactive with most substances, though not inert
Conditions to Avoid: Avoid exposure to heat, flames, strong alkalis, oxidizers
Incompatible Materials: Strong acids, strong bases, oxidizing agents, reactive metals
Hazardous Decomposition Products: Burning produces toxic fumes of carbon dioxide, carbon monoxide, nitrogen oxides
Polymerization: No known hazardous polymerization
Routes of Exposure: Eye contact, skin absorption, inhalation, ingestion
Acute Toxicity: Oral LD50 (rat): approx 3,750 mg/kg, Dermal LD50 (rabbit): above 2,000 mg/kg
Skin Corrosion/Irritation: May cause skin irritation, especially with repeated or prolonged exposure
Serious Eye Damage/Irritation: Causes moderate to severe eye irritation based on animal studies
Respiratory Sensitization: Prolonged inhalation can irritate respiratory tract
Germ Cell Mutagenicity: Data not sufficient
Carcinogenicity: Not classified as carcinogen by IARC, NTP, ACGIH or OSHA
Reproductive Toxicity: Based on animal studies, may affect fertility and fetal development
Target Organs: Liver, kidneys, central nervous system upon excessive exposure
Symptoms: Irritation, nausea, headache, dizziness, dermal redness
Toxicity to Aquatic Species: Aquatic toxicity data limited, may pose a hazard to fish and daphnia in concentrated spills
Mobility: Fully miscible in water, can spread rapidly if released
Persistence and Degradability: Not readily biodegradable, may persist in environment for extended periods
Bioaccumulation: Potential for bioaccumulation not anticipated due to physical properties
Other Adverse Effects: Large releases may alter water chemistry and pose risk to aquatic organisms; avoid environmental release whenever possible
Waste Methods: Dispose in accordance with local, regional, and national regulatory requirements for organic solvents
Container Disposal: Triple rinse and puncture empty containers before submitting to recycling or hazardous waste facility
Treatment: Suitable for incineration under controlled conditions, avoid landfill unless permitted for organic solvents with similar profiles
Precautions: Do not discharge into sewer systems, water courses, or soil
Regulatory Guidance: Consult hazardous waste codes and local chemical disposal authorities for requirements
UN Number: Not classified as hazardous for transport under most international air and ground regulations
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not assigned
Packing Group: Not regulated
Marine Pollutant: Not listed as marine pollutant
Special Precautions: Prevent spill during transport, use sealed, compatible, and appropriately labelled containers
Regulations: Subject to workplace safety standards for hazardous chemicals (OSHA Hazard Communication Standard in the US, REACH in the EU), requirements for environmental release reporting under EPA regulations for significant spills
Hazard Communication: Requires accurate labelling, safety training, and safety data sheets available at workplace
Inventory Status: Listed or notified under TSCA (US), EINECS (EU), DSL (Canada), and other key national inventories
Restrictions: Consult specific regional or national guidelines for use in consumer products, food, feed, or personal care formulations
Other Information: Keep employees informed about risks, recommended handling, and first aid through regular safety communications and training
