Material Safety Data Sheet for 1-Benzylpiperazine

Hazard Identification

Classification: Acute toxicity, oral; Skin and eye irritation; Harmful if swallowed or inhaled
Label Elements: Pictogram: Exclamation mark; Signal Word: Warning
Hazard Statements: Harmful if swallowed, may cause central nervous system stimulation, may cause skin and eye irritation
Precautionary Statements: Avoid breathing dust or vapor, wash skin thoroughly after handling, wear gloves, eye protection
Potential Health Effects: Short-term exposure may cause agitation, nausea, headache, increased heart rate; chronic exposure remains under-researched, but may increase risk for adverse mental health reactions
Environmental Hazard: Limited data on persistence or bioaccumulation, recommend prevention of uncontrolled environmental release

Composition / Information on Ingredients

Chemical Identity: 1-Benzylpiperazine
Synonyms: BZP
Concentration: 98% >
Impurities: Residual solvents or byproducts (trace amounts, supplier-specific)
Other Ingredients: None disclosed

First Aid Measures

Inhalation: Move person to fresh air, support breathing as needed, seek medical attention for respiratory distress
Skin Contact: Immediately wash with soap and water, remove contaminated clothing; seek medical attention if irritation persists
Eye Contact: Rinse eyes with plenty of water for at least 15 minutes; remove contact lenses if present and easy to do; seek medical advice
Ingestion: Rinse mouth, do not induce vomiting unless instructed by medical professionals; seek immediate medical help
Symptoms: Overexposure may cause hyperactivity, agitation, dizziness, difficulty breathing, increased heart rate
Advice to Doctor: Treat symptomatically, monitor cardiovascular and respiratory status; no specific antidote

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide
Unsuitable Extinguishing Media: Do not use direct water jet
Specific Hazards: Combustion produces toxic fumes including nitrogen oxides and carbon monoxide
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective clothing
Special Fire-Fighting Procedures: Approach from upwind, cool containers with water spray to prevent bursting; avoid breathing smoke or gases

Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel, ventilate area, avoid contact with skin and eyes, wear protective equipment
Environmental Precautions: Prevent spillage from entering drains, surface or ground water
Methods for Cleaning Up: Collect spill using non-sparking tools, absorb liquid with inert material, place in suitable closed container for disposal; clean area with detergent and water
Decontamination: Wash contaminated surface thoroughly; maintain ventilation

Handling and Storage

Handling: Use in well-ventilated area, avoid inhalation or contact with skin and eyes; handle with gloves and safety glasses, keep away from food and drinks
Storage: Store in tightly closed original container, away from incompatible substances; keep in cool, dry, well-ventilated location, protect from light and moisture, label containers clearly
Incompatibilities: Strong oxidizing agents, acids, bases
Hygiene Practices: Wash hands thoroughly after use, remove contaminated clothing and clean before reuse

Exposure Controls and Personal Protection

Exposure Limits: No established occupational exposure limits
Engineering Controls: Use chemical fume hood, ensure adequate ventilation
Personal Protective Equipment: Nitrile gloves, safety goggles, laboratory coat, respirator if airborne dust or vapor risk exists
Environmental Controls: Prevent release to environment, use spill containment
General Measures: Wash hands before breaks and after work; avoid eating, drinking, or smoking near chemical

Physical and Chemical Properties

Appearance: White or off-white crystalline powder
Odor: Mild, characteristic
Melting Point: 233-235°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, alcohol, and organic solvents
pH: Not available
Vapor Pressure: Negligible at room temperature
Density: Approx. 1.1 g/cm³
Flash Point: Not available
Evaporation Rate: Not determined
Partition Coefficient (log Kow): Not measured
Viscosity: Not applicable
Form: Solid

Stability and Reactivity

Chemical Stability: Stable under recommended handling and storage conditions
Conditions to Avoid: Excessive heat, light, moisture, incompatible materials
Incompatible Materials: Strong oxidizing agents, acids, bases
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, benzyl derivatives
Polymerization: No hazardous polymerization expected under normal use

Toxicological Information

Acute Toxicity: Causes acute stimulation of central nervous system in animals and likely in humans, potentially harmful by ingestion
Inhalation Exposure: May provoke dizziness, respiratory irritation
Skin Contact: May cause irritation, redness, dryness
Eye Contact: Irritation, redness, watering of eyes
Chronic Effects: Prolonged or repeated exposure may lead to neurotoxicity or behavioral effects
Carcinogenicity: No data indicating carcinogenic potential
Mutagenicity: Insufficient data available
Reproductive Toxicity: Insufficient data to determine effects
Signs and Symptoms: Nervousness, restlessness, headache, nausea, cardiovascular impacts

Ecological Information

Ecotoxicity: Data on aquatic and terrestrial toxicity are limited
Persistence and Degradability: Expected to be degraded in environment, but specifics not documented
Bioaccumulative Potential: Low to moderate potential anticipated, insufficient experimental evidence
Mobility in Soil: Moderate, based on structure, likely to move through soil with water
Other Adverse Effects: Spillage can disrupt aquatic systems, recommend avoiding environmental release

Disposal Considerations

Waste Treatment Methods: Incinerate or use authorized chemical disposal services in compliance with local, regional, and national regulations
Container Disposal: Triple rinse, puncture, and dispose according to hazardous waste procedures
Special Precautions: Do not dispose with general waste, avoid environmental contamination, records of disposal kept as per regulations

Transport Information

UN Number: Not assigned
UN Proper Shipping Name: Not regulated for transport in most countries
Transport Hazard Class(es): Not listed
Packing Group: Not classified
Environmental Hazards: Not classified as marine pollutant
Special Precautions: Follow national laws regarding chemicals with psychoactive properties under controlled substances acts; protect containers from breakage during transport

Regulatory Information

International Inventory Status: Not listed on major federal inventories (TSCA, EINECS)
Regulatory Classification: Controlled substance in many jurisdictions, legal status varies by country
Labeling Requirements: Hazard warning labels including emergency health and contact information
Risk Phrases: Harmful if swallowed, irritant
Safety Phrases: Keep container tightly closed and in a well-ventilated place, avoid exposure, wear suitable protective clothing
Further Regulations: Refer to national legislation for handling psychoactive substances, use only with proper licenses and authorization