Product Name: 1-Benzo[B]Thien-2-Ylethan-1-One
Chemical Formula: C10H8OS
Synonyms: 2-Acetylbenzo[b]thiophene, Benzo[b]thiophene-2-yl ethanone
CAS Number: 23801-74-3
Recommended use: Laboratory reagent, research chemical
Manufacturer: Refer to supplier label
Emergency Telephone: Contact local poison control center
Classification: Flammable solid, Harmful if swallowed, Skin irritant, Eye irritant, Hazardous to aquatic environment
Label Elements: Skull and crossbones, exclamation mark for irritant properties
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation; harmful if swallowed or inhaled; suspected of causing genetic defects; may damage fertility or the unborn child; dangerous to aquatic life with long lasting effects
Precautionary Statements: Avoid breathing dust, wash thoroughly after handling, use only outdoors or in a well-ventilated area, avoid release to the environment, wear protective gloves and eye protection
Chemical Name: 1-Benzo[B]Thien-2-Ylethan-1-One
Concentration: 98-100%
Molecular Weight: 176.24 g/mol
Impurities: Traces of unreacted starting material or by-products may be present depending on synthesis route
Inhalation: Move exposed person to fresh air. If breathing becomes difficult, get immediate medical attention. Remove any contaminated clothing.
Skin contact: Rinse exposed skin well with soap and water for at least 15 minutes. Remove contaminated clothing and wash before reuse.
Eye contact: Flush eyes immediately with plenty of running water, lifting eyelids to thoroughly rinse the surface of the eye. Seek prompt medical attention.
Ingestion: Do not induce vomiting. Rinse mouth with water and seek medical attention if symptoms appear; never give anything by mouth to an unconscious person.
Most important symptoms/effects: Irritation, reddening, possible respiratory distress with significant inhalation, abdominal discomfort if ingested
Extinguishing Media: Use foam, dry powder, or carbon dioxide as appropriate for the surrounding fire.
Unsuitable Extinguishing Media: Avoid high pressure water streams that may spread the chemical.
Specific Hazards: May emit hazardous fumes of sulfur oxides and carbon oxides under fire conditions.
Protective Equipment: Firefighters need self-contained breathing apparatus and protective clothing.
Fire/Explosion Hazards: Flammable dust explodes if dispersed in air and ignited; containers may rupture under fire conditions owing to heat.
Additional Information: Prevent runoff from entering drains, sewers or waterways.
Personal Precautions: Evacuate personnel to safe areas. Use personal protective equipment including gloves, goggles, dust mask or respirator.
Environmental Precautions: Prevent material from entering drains or surface water. Avoid soil contamination.
Methods for Cleanup: Sweep up and collect spilled material in a suitable, properly labeled waste container. Wash spill area after material pickup is complete.
Reference to other sections: Refer to Exposure Controls/Personal Protection and Disposal Considerations.
Handling: Use only in well-ventilated areas. Avoid generating and breathing dust. Avoid contact with skin, eyes, and clothing. Always use local exhaust ventilation and wear suitable personal protection.
Storage: Store in a tightly closed container. Keep in a cool, dry, well-ventilated space away from sources of ignition, incompatible substances, and direct sunlight.
Incompatibilities: Strong oxidizers, reducing agents, acids, and bases.
Engineering Controls: Use local exhaust or general room ventilation to limit exposure. Work in a chemical fume hood when possible.
Personal Protective Equipment: Wear splash-proof safety goggles and gloves made of compatible chemical-resistant material. Use a lab coat or long-sleeved clothing to reduce skin exposure.
Respiratory Protection: Use NIOSH-approved dust respirator for nuisance dusts when ventilation is insufficient.
Hygiene Measures: Wash hands thoroughly after handling. Do not eat, drink, or smoke in work areas.
Appearance: White to faintly yellow crystalline powder
Odor: Weak, characteristic aromatic
Melting Point: 72 - 74°C
Boiling Point: Decomposes
Solubility: Slightly soluble in water; more soluble in organic solvents such as ethanol, acetone, and ethyl acetate
Density: Approximately 1.28 g/cm³
Flash Point: Estimated near 105°C
Vapor Pressure: Not significant at room temperature
Other Properties: May form combustible dust concentrations in air; stable in original packaging at room temperature
Chemical Stability: Stable under normal conditions of storage and handling.
Reactivity: Reacts with strong oxidizing agents.
Conditions to Avoid: Excess heat, sources of ignition, elevated temperatures, incompatible materials
Incompatible Materials: Strong oxidizers, strong acids, strong bases
Hazardous Decomposition Products: May generate toxic gases such as carbon monoxide, carbon dioxide, and sulfur oxides upon decomposition.
Polymerization: No known hazardous polymerization may occur
Acute Effects: Harmful if swallowed or inhaled; causes irritation to eyes, skin, and mucous membranes
Chronic Effects: No long-term studies in humans are available; structurally similar compounds have displayed effects on the liver and central nervous system.
Routes of Exposure: Inhalation, ingestion, skin contact
LD50 (oral, rat): Estimated >500 mg/kg
Symptoms of Overexposure: Burning or itching sensation, coughing, headache, nausea
Carcinogenicity: Not listed by NTP, IARC, or OSHA as a carcinogen.
Mutagenicity: Data is lacking for this material, similar chemicals have tested negative in standard assays; precaution warranted
Toxicity: Harmful to aquatic organisms; may cause long-term effects in the aquatic environment
Persistence and Degradability: Expected to be poorly biodegradable based on structure
Bioaccumulation Potential: Moderate to high potential
Mobility in Soil: Low water solubility; strong adsorption to soil anticipated
Other Adverse Effects: Chemical waste may affect surface and groundwater; follow proper waste management practices to prevent environmental release
Disposal Methods: Dispose of as hazardous chemical waste in accordance with local, regional, and national regulations. Incineration recommended under controlled conditions in approved facilities.
Container Disposal: Rinse container thoroughly before disposal. Do not reuse empty containers.
Precautions: Do not allow into sewer, soil, surface water, or groundwater; label waste containers clearly and keep securely closed until disposal
UN Number: 2811
UN Proper Shipping Name: Toxic solid, organic, n.o.s. (contains 1-Benzo[B]Thien-2-Ylethan-1-One)
Transport Hazard Class: 6.1 (Toxic Substances)
Packing Group: III
Marine Pollutant: Yes
Special Precautions: Avoid breakage; keep product away from food and feedstuffs during transit
Regulatory Transport Statements: Comply with all international, national, and local transport regulations
US Federal Regulations: SARA Title III Section 313 not listed; consult TSCA inventory for up-to-date status
EU Regulations: Not classified according to REACH Annex XVII, CLP Regulation EC No 1272/2008; Safety data sheet required for all supplied quantities
Other International Standards: Ensure compliance with country-specific requirements for chemical handling, storage, and transport
Workplace Exposure Limits: Not established; recommended threshold limit value (TLV) may be extrapolated from similar chemicals—use caution
