Product Name: 1-Aminopyrrolidine
Synonyms: Pyrrolidin-1-amine, Pyrroline amine, 1-Pyrrolidinamine
CAS Number: 1121-75-7
EC Number: 214-340-3
Manufacturer: [Insert supplier/manufacturer information]
Recommended Use: Laboratory chemical, chemical synthesis
Contact Details: [Provide emergency number, e-mail, supplier address]
Restrictions: Not intended for drug, food, or cosmetic use
GHS Classification: Flammable liquid (Category 3), Acute toxicity—oral (Category 4), Skin corrosion/irritation (Category 2), Serious eye damage/eye irritation (Category 2A)
Pictograms: Flame, Exclamation mark
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.
Precautionary Statements: Keep away from heat, sparks, open flames; no smoking. Wear protective gloves, clothing, and eye/face protection. Wash hands thoroughly after handling. Avoid breathing vapor or mist. In case of fire, use dry chemical, foam, or CO2.
Potential Health Effects: Inhalation causes respiratory tract irritation, headaches, dizziness. Skin contact causes irritation, redness, possible burns from prolonged exposure. Eye contact causes pain, redness, watering, and blurred vision. Swallowing may result in nausea, vomiting, and abdominal pain.
Chemical Identity: 1-Aminopyrrolidine
Common Name and Synonyms: Pyrrolidine amine, N-Aminopyrrolidine
CAS Number: 1121-75-7
Concentration: >98% (for laboratory grade samples)
Impurities and Stabilizing Additives: Product purity and impurity profile available from the supplier upon request
Inhalation: Move person to fresh air, provide artificial respiration if breathing stops, keep individual calm and warm, seek medical help immediately for persistent symptoms.
Skin Contact: Remove contaminated clothing and shoes, rinse affected skin thoroughly with plenty of water (at least 15 minutes), use mild soap if available, consult a physician if irritation persists.
Eye Contact: Flush eyes with copious amounts of water for at least 15 minutes, keep eyelids apart to ensure thorough rinsing, remove contacts if present and safe to do so, get medical attention without delay.
Ingestion: Rinse mouth with water, do not induce vomiting unless directed by medical personnel, give water if conscious, seek immediate medical assistance.
Most Important Symptoms: Burning sensation, dermatitis, eye discomfort, nausea, dizziness; medical observation may be needed.
Suitable Extinguishing Media: Dry chemical, foam, alcohol-resistant foam, CO2, water spray, avoid direct water stream due to risk of splash.
Unsuitable Media: Direct water jets
Specific Hazards: Emits toxic gases (nitrogen oxides, carbon oxides) on combustion. Vapors may form explosive mixtures with air.
Advice for Firefighters: Wear self-contained breathing apparatus, chemical-resistant suit, remain upwind and avoid smoke. Use water spray to cool containers.
Additional Considerations: Containers exposed to fire may rupture; removal or cooling is key to safety.
Personal Precautions: Evacuate area, ventilate space, shut off ignition sources, equip personnel with gloves, goggles, and respirator.
Environmental Precautions: Prevent from entering sewers, drains, or waterways; notify relevant authorities if contamination is likely.
Spill Response: Absorb with inert material (earth, sand, vermiculite), transfer to chemical waste cans, clean spill area with plenty of water, ventilate, dispose of according to local legislation.
Cleanup Tools: Shovel, non-sparking tools, absorbent pads recommended for complete removal.
Handling: Avoid contact with skin, eyes, clothing; do not inhale vapors, use in well-ventilated spaces or with appropriate exhaust systems; ground equipment when transferring material, handle away from sources of heat and ignition.
Storage: Store in tightly sealed container, keep in cool, dry, well-ventilated area, keep away from direct sunlight and incompatible materials like oxidizing agents and strong acids.
Special Instructions: Label storage area clearly, restrict access to trained staff, install spill containment if large volumes are stored.
Control Parameters: No established occupational exposure limits for 1-Aminopyrrolidine, use exposure limits for amines if available for reference.
Engineering Controls: Use chemical fume hood, mechanical exhaust recommended for indoor work.
Personal Protective Equipment (PPE): Chemical-resistant gloves (nitrile, neoprene), tightly fitting chemical splash goggles, lab coat or apron, closed shoes; for large-scale or industrial settings, use full-face respirator.
Hygiene Measures: Wash thoroughly after handling, change contaminated clothing, keep food and drinks away from the workplace.
Form: Colorless to pale yellow liquid
Odor: Amine-like, strong, unpleasant
Boiling Point: 139°C
Melting Point: -45°C
Flash Point: 47°C (closed cup)
Vapor Pressure: 5 mmHg at 25°C
Solubility: Miscible with water, alcohol, and ether
Density: 0.97 g/cm³
pH (in aqueous solution): Basic
Viscosity: Low viscosity liquid
Partition Coefficient (log Pow): Not readily available; likely low due to solubility
Autoignition Temperature: 275°C
Explosion Limits: Not precisely defined, ensure monitoring for flammable range during use.
Chemical Stability: Stable under suggested storage and handling. Decomposes on excessive heating, exposure to strong acids, oxidizing agents or sunlight.
Possibility of Hazardous Reactions: Reacts with acids, oxidants, and halogens rapidly, can react vigorously under improper conditions causing toxic fume release.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, toxic organic fumes.
Incompatible Materials: Strong acids, oxidizing agents, acid chlorides, anhydrides
Conditions to Avoid: Heat, flame, sparks, sources of ignition, moisture ingress leading to container corrosion.
Potential Routes of Exposure: Inhalation, ingestion, skin contact, eye contact.
Acute Toxicity Data (if known): LD50 (oral, rat): ~350 mg/kg
Chronic Effects: Prolonged skin contact can cause dermatitis; repeated inhalation may affect organ function due to amine sensitization.
Symptoms: Irritation, burning pain, coughing, nausea, dizziness, blurred vision.
Sensitization: Potential for skin and respiratory sensitization in some cases.
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Insufficient data on carcinogenic, mutagenic or teratogenic effects.
Aquatic Toxicity: Data not fully available; as an amine, may be harmful to aquatic organisms, particularly at high concentrations.
Persistence and Degradability: Moderately biodegradable; may persist in certain soil and water environments.
Bioaccumulative Potential: Low, likely rapid metabolism in environment
Mobility in Soil: High mobility due to water miscibility, can contaminate groundwater if released.
Other Adverse Effects: Runoff may cause oxygen depletion in water bodies, disrupt aquatic life in local concentrations.
Disposal Containers: Place unused material into sealed, labeled chemical waste containers.
Methods of Disposal: Use authorized chemical disposal contractor, incineration recommended for small quantities in a controlled facility, avoid landfill disposal.
Special Instructions: Do not pour down drains or discharge into environment; rinse empty containers before recycling or discarding according to local regulations.
Legal Requirements: Adhere to all regional, national and international guidelines for hazardous chemical waste.
UN Number: 2734
Proper Shipping Name: Amines, liquid, corrosive, flammable, n.o.s. (contains 1-Aminopyrrolidine)
Transport Hazard Class: 3 (flammable liquid), 8 (corrosive)
Packing Group: II
Environmental Hazards: Not classified for marine pollution, but bulk accidental release remains a risk
Special Precautions: Ensure containers are upright, tightly closed, segregated from oxidizers and acids during transit; mark with appropriate labels (flammable, corrosive).
Classification: Controlled as a hazardous chemical under OSHA (USA), EU CLP, and analogous standards worldwide.
Inventory Status: Listed in TSCA, EINECS, DSL, AICS; check compliance with relevant regional chemical inventories.
Label Elements: Signal word “Warning”, hazard pictograms, hazard and precautionary statements under GHS and local rules.
Restrictions: Certain jurisdictions may require notification or approval for quantities above threshold limits.
Other Regulatory References: Consult country-specific workplace safety, transport, and environmental regulations for up-to-date compliance details.
