Chemical Name: 1-Aminopyrrole
Chemical Formula: C4H6N2
CAS Number: 3973-54-6
Synonyms: Pyrrol-1-amine, Aminopyrrole
Recommended Uses: Research chemical, intermediate for pharmaceuticals
Restrictions on Use: Only trained professionals in a controlled environment should handle
Manufacturer/Supplier Information: Check primary supplier for specific details; keep contact information readily available at the worksite
GHS Classification: Acute toxicity (oral, dermal, inhalation), Skin irritant, Eye irritant
Signal Word: Danger
Hazard Statements: May cause skin irritation, can be harmful if swallowed, risk of eye irritation, inhalation risks include respiratory tract irritation
Precautionary Statements: Avoid all contact with skin and eyes, do not breathe dust/vapor/mist, always use protective gear
Symbol(s): Exclamation mark, skull and crossbones for toxicity
Health Hazards: High exposure can lead to nausea, headache, dizziness, possibly respiratory distress
Environmental Hazards: Persistent in soil and water, potentially harmful to aquatic life if released in volume
Substance: 1-Aminopyrrole (C4H6N2)
Concentration: Typically supplied as >98% pure solid or in solution (consult supplier data)
Impurities/Decomposition Products: Minor pyrrole derivatives, trace water content may be present, decomposition may produce nitrogen oxides and carbon oxides
General Advice: Move affected person away from exposure area immediately, get medical attention fast
Inhalation: If someone inhales vapors or dust, bring them to fresh air, support breathing with oxygen if needed, seek immediate medical advice
Skin Contact: Remove contaminated clothing; wash exposed skin thoroughly with soap and water for at least 15 minutes
Eye Contact: Rinse eyes with large amounts of water for 15 minutes, hold eyelids open—do not rub eyes
Ingestion: Do not induce vomiting, rinse mouth with water if conscious, never give anything by mouth to an unconscious person, rush to medical help
Symptoms to Watch: Rashes, redness, coughing, headache, burning sensation, stomach upset
Suitable Extinguishing Media: Dry chemical powder, alcohol-resistant foam, CO2, water spray—avoid direct water jets
Specific Hazards: Releases toxic fumes of nitrogen oxides, carbon monoxide under fire; highly flammable—vapors may form explosive mixtures with air
Special Protective Equipment: Firefighters need to use self-contained breathing apparatus—protective full-body gear
Advice for Fire Responders: Use water spray to cool containers near fire, stay upwind, evacuate area if massive quantities go up in smoke
Personal Precautions: Evacuate unnecessary personnel—use proper protective equipment, avoid breathing vapors or contacting skin
Environmental Precautions: Prevent chemical from reaching drains, sewers, surface water, or soil
Containment Methods: Stop leak if possible, absorb spill with inert material (sand, vermiculite), place waste in container for disposal
Cleanup Procedures: Collect and dispose in accordance with local regulations, ventilate area thoroughly, decontaminate surfaces with appropriate cleaner—never return spilled material to original container
Handling: Work in well-ventilated area or chemical fume hood—avoid generation of dust, minimize inhalation or direct contact, never eat, drink, or smoke during handling
Storage: Store in tightly sealed original container, label properly, keep in cool, dry space away from direct sunlight, incompatible substances like strong oxidants, acids, or bases
Other Precautions: Store below 25°C, segregate from food and feedstuffs, limit access to trained personnel, use secondary containment when possible
Occupational Exposure Limits: Not established specifically for 1-Aminopyrrole, but minimize chronic exposure to low levels
Engineering Controls: Use chemical fume hood, maintain local exhaust, keep work area well ventilated all times
Personal Protective Equipment: Wear chemically resistant gloves (nitrile or neoprene), safety goggles or face shield, lab coat, closed toe shoes
Respiratory Protection: Use NIOSH-approved respirator if ventilation is inadequate or significant airborne exposure is possible
Hygiene Measures: Wash hands thoroughly after use, remove and clean contaminated clothing before reuse, avoid touching face while working
Appearance: Colorless to pale yellow liquid or low-melting solid
Odor: Mild, ammonia-like smell
Molecular Weight: 82.10 g/mol
Melting Point: 65-67°C (depends on purity)
Boiling Point: Approximately 200°C at atmospheric pressure
Density: 1.12 g/cm³ (approximate, liquid)
Solubility: Soluble in most organic solvents—poor solubility in water
pH (of solution): Slightly basic
Vapor Pressure: Low at standard temperatures
Stability: Air and light sensitive—tends to darken or polymerize slowly in storage
Chemical Stability: Stable under standard temperatures and dry conditions, but breaks down under sustained heat, UV, or air exposure
Incompatible Materials: Strong oxidizers, mineral acids, hypochlorites—risk of hazardous reaction
Hazardous Decomposition: Can release toxic nitrogen oxides, carbon monoxide, and unidentified organic fragments on burning or decomposition
Polymerization: No dangerous polymerization expected under normal handling, but polymerizes slowly if left exposed to air and light
Routes of Exposure: Absorption through skin, inhalation of vapors, ingestion
Acute Effects: Causes skin and eye irritation, potential for systemic toxicity if enough is absorbed
Chronic Effects: Data on long-term effects is limited; similar compounds may impact liver and kidneys—avoid repeat exposure
LD50 (Oral, Rat): Estimated 400 mg/kg—can vary significantly by batch and exposure conditions
Symptoms: Skin redness, headache, nausea, dizziness, respiratory irritation
Carcinogen Status: Not classified as carcinogenic according to IARC, limited data available
Ecotoxicity: Likely toxic to aquatic organisms at low concentrations, especially in enclosed systems
Persistence and Degradability: Not readily biodegradable, long half-life in cold water or soil
Bioaccumulative Potential: Unlikely to build up in organisms due to water solubility, but needs monitoring
Mobility in Soil: Mobile if spilled—can leach, especially during rain or run-off
Other Harmful Effects: Can negatively affect microorganisms in wastewater treatment
Product Disposal: Incinerate at approved facility whenever possible—do not pour down drain or discard in trash
Contaminated Packaging: Triple rinse containers, dispose of as hazardous chemical waste
Sewage Disposal Recommendations: Do not discharge into municipal systems, waterways, or soil—contact local hazardous waste authorities
Additional Notes: Always use properly labeled containers and complete required waste manifests
UN Number: Only assigned for some derivatives—check regulations based on shipping region
Proper Shipping Name: 1-Aminopyrrole, Chemical, n.o.s.
Transport Hazard Class: Flammable, toxic (consult regional regulations)
Packing Group: II or III, depending on concentration
Precautions for Transport: Ship in tightly sealed chemical containers, use absorbent material in case of leaks, keep upright in cool, well-ventilated space
Special Regulations: Must comply with local, national, and international hazardous goods rules—mark packages clearly with hazard labels and shipping papers
OSHA Classification: Hazardous Chemical
SARA Title III: Not listed as an extremely hazardous substance, but regulated under hazardous chemical reporting
TSCA: Listed or reportable in the United States
REACH Status: Consult supplier for EU registration status—not widely registered as of 2024
Workplace Regulations: Facilities must keep MSDS access, spill control kits, emergency wash stations
Other Directives: Waste generators and carriers need to keep proper shipping documentation and follow hazardous waste rules specific to region
