Product Name: 1,4-Diazabicyclo[2.2.2]octane
Synonyms: DABCO; Triethylenediamine; TEDA
CAS Number: 280-57-9
Recommended Use: Curing agent, catalyst for polyurethane and epoxy resins, corrosion inhibitor, chemical synthesis
Supplier: Registered chemical distributors, research chemical manufacturers
Emergency Contact: Refer to regional chemical helpline or poison control center
Classification (GHS): Acute toxicity (oral, dermal, inhalation)—Category 4; Eye irritation—Category 2A; Skin irritation—Category 2
Signal Word: Warning
Hazard Statements: Harmful if swallowed or inhaled; Causes skin and eye irritation
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust or vapor; Wash hands thoroughly after handling; Wear protective gloves, clothing, and eye protection
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Target Organs: Eyes, skin, respiratory system
NFPA Ratings: Health: 2, Fire: 1, Reactivity: 0
Chemical Name: 1,4-Diazabicyclo[2.2.2]octane
Concentration: ≥98% (pure substance)
CAS Number: 280-57-9
Impurities and Stabilizing Additives: Not significant for standard laboratory material
Molecular Formula: C6H12N2
Molecular Weight: 112.17 g/mol
Inhalation: Move exposed person to fresh air; seek medical attention for prolonged symptoms; provide oxygen if breathing is difficult
Skin Contact: Remove contaminated clothing; rinse skin with soap and water for at least 15 minutes; consult physician if irritation persists
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing; get medical advice if irritation remains
Ingestion: Rinse mouth; do not induce vomiting; call medical help immediately; provide symptomatic support only
Note to Physicians: Treat with supportive measures as required; symptoms may be delayed
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: Direct water stream on burning solid may spread fire
Special Hazards from Combustion: Emits toxic fumes including nitrogen oxides and carbon oxides
Protective Equipment: Use self-contained breathing apparatus and full protective gear
Specific Firefighting Measures: Contain run-off; cool exposed containers with water spray; avoid breathing smoke or gases
Personal Precautions: Use appropriate PPE; avoid inhalation of dust; avoid skin and eye contact; ensure adequate ventilation
Environmental Precautions: Prevent further leakage or spillage where safe to do so; avoid discharge to waterways and sewers
Containment Methods: Sweep up and collect spillage; prevent dust formation; place in appropriate labeled containers
Cleanup Procedures: Wet brushing or vacuum with appropriate filter; wash residue from area with plenty of water; check for compatibility with cleaning equipment to avoid unwanted reactions
Handling: Handle in a chemical fume hood; use protective gloves, eyewear, and clothing; avoid breathing dust; avoid contact with skin and eyes; do not eat, drink, or smoke near substance; wash hands thoroughly after use
Storage: Store in cool, dry, well-ventilated area; keep container tightly closed; store away from strong acids, oxidizers, and moisture; keep separate from food and drink; use corrosion-resistant shelving
Incompatibilities: Strong oxidizing agents, acids, halogens; may react with CO2 to form solid carbamate
Occupational Exposure Limits: No established OSHA PEL or ACGIH TLV for DABCO; keep airborne levels as low as possible
Engineering Controls: Local exhaust ventilation necessary; use process enclosures or fume hoods; eye wash stations and emergency showers should be available
Personal Protective Equipment: Safety goggles/glasses, chemical-resistant gloves (nitrile, butyl rubber), lab coat or chemical-resistant clothing, NIOSH-approved respirator for dust or inadequate ventilation scenarios
Hygiene Measures: Remove PPE and wash skin thoroughly; do not reuse contaminated clothing until cleaned
Appearance: White crystalline solid, powder
Odor: Ammonia-like
Odor Threshold: Not available
pH: Alkaline aqueous solutions
Melting Point: 158-159°C (316-318°F)
Boiling Point: Decomposes before boiling
Flash Point: 114°C (237°F)
Flammability: Combustible solid
Explosion Limits: Not established
Vapor Pressure: Low at room temperature
Solubility: Soluble in water; also dissolves in alcohols and acetone
Partition Coefficient (log Kow): -1.29 (estimated)
Vapor Density: Not applicable
Evaporation Rate: Not applicable
Relative Density: ~1.14 g/cm³
Auto-ignition Temperature: Not established
Viscosity: Not applicable (solid)
Chemical Stability: Stable under recommended storage and handling conditions
Possibility of Hazardous Reactions: May react with strong acids forming heat and fumes; formation of solid carbamates with CO2
Conditions to Avoid: Excess moisture, elevated temperature, exposure to CO2 in confined spaces, ignition sources
Incompatible Materials: Strong oxidizers, acids, haloalkanes, CO2
Hazardous Decomposition Products: Toxic gases including nitrogen oxides, carbon oxides
Routes of Exposure: Inhalation, skin, eye contact, ingestion
Acute Toxicity: LD50 (oral, rat): 970 mg/kg; LD50 (dermal, rabbit): >2000 mg/kg
Symptoms: Irritation to mucous membranes, eyes, skin; respiratory discomfort, coughing, headache from inhalation
Corrosivity/Irritation: Can irritate skin, eyes, and respiratory tract
Sensitization: Data not sufficient for classification
Chronic Effects: Repeated/prolonged exposure may lead to dermatitis or respiratory irritation
Carcinogenicity: Not listed as carcinogen by IARC, NTP, OSHA
Mutagenicity/Reproductive Toxicity: Insufficient data on mutagenic or reproductive effects
Aquatic Toxicity: Low to moderate toxicity; EC50 (Daphnia, 48 hr): 37 mg/L; harmful in larger concentrations to aquatic organisms
Persistence and Degradability: Expected to be biodegradable; will not persist in water or soil
Bioaccumulative Potential: Low, based on partition coefficient
Mobility: Readily mobile in aqueous environments
Other Effects: Avoid discharge in natural water or soil; large spills increase oxygen demand in water, impacting aquatic life
Waste from Residues: Dispose of in accordance with federal, state, and local environmental control regulations; consult licensed waste disposal company
Contaminated Packaging: Rinse and dispose safely, follow regulations for hazardous waste
Treatment: Must not enter sewers, surface water, or soil
Incineration: Suitable for properly permitted facility, with proper controls for emission of nitrogen oxides
UN Number: Not regulated as hazardous for ground, air, or sea transport in most regions
Proper Shipping Name: 1,4-Diazabicyclo[2.2.2]octane
Hazard Class: Not classified
Packing Group: Not assigned
Environmental Hazards: Not classified as a marine pollutant
Special Precautions for Transport: Protect from physical damage, moisture, and heat during transport; ensure container integrity; follow national and local transport regulations
SARA 313: Not listed
TSCA Inventory: Listed
REACH Status: Registered / pre-registered in the EU
OSHA Hazard Communication: Considered hazardous chemical
Canadian DSL/NDSL: Listed on DSL
RoHS, SVHC: Not listed as a substance of very high concern
Labeling: In accordance with local, regional, and global chemical safety regulations, ensure appropriate warning labels and safety data accompany the product during sale and shipping
