Product Name: 1-(2-Hydroxyethyl)Pyrrolidine-2,5-Dione
Chemical Formula: C6H9NO3
CAS Number: 5290-45-1
Synonyms: Succinimide, N-(2-Hydroxyethyl)-; N-(2-Hydroxyethyl)succinimide
Recommended Use: Laboratory reagent, intermediate in organic synthesis
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Classification (GHS): Not classified as hazardous according to GHS criteria
Pictogram: Not required
Signal Word: Not required
Hazard Statements: Non-hazardous under normal handling and use
Precautionary Statements: Avoid inhalation, skin, and eye contact. Use in ventilated space.
Potential Health Effects: May cause mild irritation to eyes, skin, or respiratory tract on repeated exposure.
Environmental Hazards: Thought not to be hazardous to environment in small laboratory quantities, but large spills could affect water quality.
Chemical Name: 1-(2-Hydroxyethyl)Pyrrolidine-2,5-Dione
Common Name: N-(2-Hydroxyethyl)succinimide
CAS Number: 5290-45-1
Percentage in Product: 98–100% (w/w)
Impurities: Trace synthetic impurities below 1%
Other Ingredients: None disclosed
Eye Contact: Rinse immediately with plenty of cold water for at least 15 minutes, holding eyelids apart. Get medical attention if symptoms persist.
Skin Contact: Remove contaminated clothing. Wash skin with mild soap and water. Seek medical help for persistent irritation.
Inhalation: Move to fresh air if dust or vapors are inhaled. Get medical advice if symptoms continue.
Ingestion: Rinse mouth with water; never give anything by mouth to an unconscious person. Call a physician if large amounts are ingested.
Most Important Symptoms/Effects: Mild irritation, redness, or discomfort at exposed sites.
Suitable Extinguishing Media: Water mist, dry chemical powder, alcohol-resistant foam, carbon dioxide
Unsuitable Extinguishing Media: Avoid strong water jets
Specific Hazards from Burning: May produce nitrogen oxides and carbon monoxide on thermal decomposition
Protective Equipment: Firefighters use self-contained breathing apparatus, protective clothing
Firefighting Advice: Cool exposed containers with water spray, prevent runoff from entering drains
Personal Precautions: Avoid breathing dust, provide adequate ventilation; wear gloves and eye protection
Environmental Precautions: Prevent solid from entering drains or waterways; inform local authorities if large quantities spill
Cleanup Methods: Collect spill with non-combustible absorbent material, sweep into suitable container and close tightly for disposal; clean residue with water
Handling: Work in well-ventilated spaces, avoid contact with skin and eyes, keep containers tightly closed when not in use; never eat or drink in working area
Storage: Store cool, dry place, away from direct sunlight, strong oxidizing agents, and moisture
Storage Conditions: Recommended temperature below 25°C, protect from humidity
Container Materials: Use compatible, properly labeled containers
Special Requirements: Ground and bond metal containers for large quantities to avoid static discharge
Occupational Exposure Limits: No specific limits set by OSHA, ACGIH, NIOSH
Engineering Controls: Laboratory fume hood or local exhaust to keep airborne levels low
Personal Protective Equipment (PPE): Safety goggles, chemical-resistant gloves (nitrile or latex), laboratory coat
Hygiene Measures: Wash thoroughly after handling; do not eat, drink, or smoke where product is used or stored
Respiratory Protection: For dust formation, use dust mask or respirator approved for particulates
Environmental Controls: Prevent release to environment, keep away from drains
Appearance: White to off-white crystalline solid
Odor: Odorless
Odor Threshold: Not determined
pH (1% soln): Approx. 5–7
Melting Point/Freezing Point: 112–116°C
Boiling Point: Not determined (decomposes)
Flash Point: Not applicable
Evaporation Rate: Not determined
Flammability: Not flammable
Vapor Pressure: Negligible at room temperature
Solubility: Soluble in water and alcohol
Partition Coefficient (Log Kow): Not determined
Decomposition Temperature: >200°C
Viscosity: Not applicable
Chemical Stability: Stable under normal laboratory conditions
Reactivity: Not reactive under ambient conditions with typical materials
Conditions to Avoid: Excessive moisture, strong heat, direct light
Incompatible Materials: Strong oxidizers, strong acids
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide
Polymerization: Product does not polymerize
Likely Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Toxicity: No data specific for this compound; similar structures show low toxicity
Skin Corrosion/Irritation: May cause mild irritation on prolonged contact
Serious Eye Damage/Irritation: May result in temporary discomfort or redness
Respiratory Sensitization: Low probability based on structure
Carcinogenicity: Not listed by IARC, NTP, OSHA
Germ Cell Mutagenicity: Not established
Reproductive Toxicity: No evidence from available studies
Long-Term Effects: Chronic exposure data unavailable; avoid frequent, long-term exposure
Toxicity Data: Not determined for this product; similar compounds suggest oral LD50 above 2000 mg/kg (rat)
Ecotoxicity: Not tested directly for aquatic or terrestrial toxicity; neutral pH and water solubility hint at moderate impact in large spills
Persistence and Degradability: Expected to degrade slowly in the environment
Bioaccumulative Potential: Not expected, given low octanol-water partition coefficient
Mobility in Soil: Soluble, likely to move with water
Other Adverse Effects: No known special adverse effects stated in public databases
Disposal Methods: Dispose according to federal, state, and local regulations. Dissolve small amounts in water and flush with plenty of water in accordance with local wastewater rules if permitted.
Incineration: Appropriate when in compliance with environmental authority guidance
Contaminated Packaging: Triple-rinse containers before recycling or disposal; dispose in an approved landfill or incinerator
Special Precautions: Do not discharge to natural water bodies or storm drains in large amounts
UN Number: Not assigned
Proper Shipping Name: Not regulated for transport
Transport Hazard Class: Not classified as hazardous material
Packing Group: Not applicable
Environmental Hazards: Not considered hazardous for transport
Special Precautions for User: Use appropriate packaging to avoid breakage and leaks during transit
U.S. TSCA: Listed
EU REACH: Not specifically listed
OSHA: Not classified as hazardous
SARA Title III: Not subject to reporting under Sections 302, 304, or 313
California Proposition 65: Not listed
Other International Regulations: No restrictions known in Japan, Canada, Australia or other major jurisdictions
Labelling Requirements: Standard chemical labeling sufficient for non-hazardous laboratory chemical
