Product Name: 1-(2-Furoyl)Piperazine
Chemical Formula: C9H12N2O2
CAS Number: 5801-99-0
Synonyms: N-(2-Furoyl)piperazine, 2-Furoylpiperazine
Recommended Use: Laboratory reagent, pharmaceutical intermediate
Supplier: Company contact details on request
Emergency Contact: Refer to local, regional, and national regulations for emergency support
Restrictions: Not for food, drug, or household use
Classification: Eye irritant, skin sensitizer, harmful if swallowed
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, may cause allergy or asthma symptoms, toxic to aquatic organisms
Precautionary Statements: Avoid breathing dust or fumes, wear eye and skin protection, wash hands thoroughly after handling, do not eat or drink while using
Label Elements: Exclamation mark, health hazard pictogram
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Specific Target Organ Toxicity: Data limited, exercise caution with all forms of exposure
Chemical Name: 1-(2-Furoyl)Piperazine
Common Name: 2-Furoylpiperazine
CAS Number: 5801-99-0
Concentration: 98% or above
Impurities: Trace secondary amines, possible traces of solvent residues from synthesis
Stabilizing Additives: None specified
Inhalation: Move person to fresh air, provide artificial respiration if not breathing, seek medical attention
Skin Contact: Immediately wash with plenty of soap and water for at least 15 minutes, remove contaminated clothing, consult physician
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy, continue rinsing, get medical help
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical advice
Most Important Symptoms and Effects: Irritation, allergic reactions, respiratory distress possible with prolonged exposure
Special Notes for Medical Providers: Symptomatic treatment, monitor respiratory symptoms, perform supportive therapy as needed
Extinguishing Media: Use dry chemical, carbon dioxide, water spray, or foam
Unsuitable Media: Avoid high-volume water spray
Fire Hazards: May emit toxic fumes under fire conditions, especially nitrogen oxides, carbon monoxide, furans
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Special Procedures: Cool containing vessels with water spray, prevent fire-fighting runoff from entering drains
Combustion Products: Carbon oxides, nitrogen oxides, possibly furfural
Personal Protection: Evacuate unnecessary personnel, ventilate area, use gloves, safety goggles, lab coat, respirator if needed
Containment: Prevent further leakage or spillage, use non-sparking tools
Cleanup: Scoop or vacuum dispersed material, avoid creating dust, place in appropriate waste container
Environmental Precautions: Prevent entry to sewers and surface waterways, notify environmental agencies if significant spill occurs
Decontamination: Wash contaminated area with water and detergent, dispose of cleaning materials as hazardous waste
Handling: Use only in well-ventilated areas, avoid breathing dust, use personal protective equipment, handle away from heat or open flames
Hygiene Measures: Wash hands, forearms, and face after working with the compound, keep food and drink away from work area
Storage: Store in cool, dry, well-ventilated place, keep container tightly closed, protect from moisture and direct sunlight
Storage Incompatibilities: Strong oxidizing agents, acids, bases
Container Materials: Preferably use amber glass with appropriate chemical resistance
Exposure Limits: No occupational exposure limits established, minimize exposure as best practice
Engineering Controls: Chemical fume hood, local exhaust ventilation
Personal Protective Equipment: Nitrile gloves, protective safety goggles, lab coat or coveralls, dust mask or respirator with appropriate filter
Environmental Controls: Control contaminants at source, use spill containment strategies, monitor air quality periodically
Special Instructions: Emergency shower and eye wash station accessible
Appearance: Off-white to pale yellow crystalline powder
Odor: Mild, slightly aromatic
Molecular Weight: 180.20 g/mol
pH: Not applicable (solid)
Melting Point: 104–108°C
Boiling Point: Decomposes before boiling
Flash Point: Data not specified
Solubility: Moderately soluble in water, soluble in organic solvents (ethanol, DMSO)
Vapor Pressure: Not determined
Density: ~1.22 g/cm³
Partition Coefficient: Not established
Chemical Stability: Stable under recommended storage conditions, avoid long exposure to heat or moisture
Reactivity: May react with strong acids, oxidizers, alkali
Hazardous Reactions: Generates toxic fumes when heated or decomposed, avoid contact with incompatible materials
Decomposition Products: Carbon oxides, nitrogen oxides, furfural-type compounds
Polymerization: Polymerization not anticipated under normal conditions
Acute Toxicity: Oral LD50 (rat) data not available, low to moderate toxicity expected based on structure
Skin Corrosion/Irritation: May cause dryness or cracking, irritation possible on prolonged contact
Eye Damage/Irritation: May result in redness, watering, discomfort, risk of lasting injury if not promptly treated
Respiratory Sensitization: Inhalation of dust or fumes may irritate nose, throat, and lungs
Skin Sensitization: May provoke allergic reaction in sensitive individuals
Carcinogenicity: No components listed as carcinogen by IARC, NTP, or OSHA
Mutagenicity: Insufficient data, employ standard laboratory safety precautions
Reproductive Toxicity: No animal studies available, avoid exposure if pregnant or lactating
Chronic Effects: Long-term exposure effects not reported, handle as a potential hazard
Eco-Toxicity: Harmful to aquatic life, avoid environmental contamination
Persistence/Degradability: May persist in environment, degradation pathways not fully characterized
Bioaccumulation Potential: Not expected to bioaccumulate significantly, further studies required
Mobility in Soil: Likely moderate mobility due to partial solubility in water
Other Effects: Do not allow undiluted product or large quantities to reach ground water, watercourses, or sewage systems
Waste Disposal Methods: Dispose as hazardous chemical waste, use licensed chemical waste contractor
Product Disposal: Incinerate in accordance with local, regional, and national requirements
Packaging Disposal: Triple rinse containers, puncture or otherwise render unusable before disposal in qualified landfill or by appropriate incineration
Additional Precautions: Do not discharge to drains, soil, or water bodies, document controls and final disposal
Regulatory Status: Follow all applicable hazardous waste disposal regulations
UN Number: Not assigned
Proper Shipping Name: Not regulated for transport under most international guidelines
Hazard Class: Chemical not classified as hazardous for ground, air, or sea shipment; check local regulations
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Special Precautions: Ship in sealed, labeled containers, prevent spillage during transit, secure packaging against damage and leaks
US Federal Regulations: Not listed on SARA 313, or TSCA Inventory, laboratories must comply with OSHA chemical hygiene requirements
EU Regulations: Substance not indexed in EINECS or REACH, subject to standard chemical safety assessment obligations
Other Global Inventories: Data availability varies by country, consult relevant national and regional regulatory authorities
Labeling Requirements: GHS-compliant hazard and precautionary statements, clear labeling of all primary and secondary containers
Worker Protection: Chemical hygiene plan required, risk assessments to be reviewed and updated periodically
Restrictions: Not for medicinal, food, or cosmetic use, ensure tracking and accountability in laboratory usage
