Product Name: 1-(2-Chloroethyl)Piperidinium Chloride
Synonyms: N-(2-Chloroethyl)piperidinium chloride
Chemical Formula: C7H16Cl2N
CAS Number: 2079-89-2
Recommended Uses: Laboratory chemicals, chemical research and development
Manufacturer: Laboratory Supply Companies, Chemical Vendors
Contact Information: Emergency phone number and address listed by supplier on label
Emergency Overview: White to off-white crystalline powder, slight amine odor, hygroscopic, soluble in water
Classification: Acute toxicity (oral, dermal, inhalation), skin and eye irritant, suspected mutagenic agent, neurotoxin potential
GHS Label Elements: Skull and crossbones, Exclamation mark
Pictograms: GHS06 (Toxic), GHS07 (Harmful/Irritant)
Signal Word: Danger
Hazard Statements: Toxic in contact with skin or if swallowed. Causes severe skin burns and eye damage. May cause respiratory irritation. Suspected of causing genetic defects.
Precautionary Statements: Do not breathe dust or vapors. Wash skin thoroughly after handling. Use only with adequate ventilation. Wear protective gloves, protective clothing, eye protection, and face protection.
Target Organs: Nervous system, eyes, skin, respiratory system.
Symptoms of Overexposure: Burning sensation, coughing, headache, dizziness, nausea, twitching, possible convulsions.
Chronic Effects: Long-term exposure may affect central nervous system and may pose a cancer risk.
Chemical Name: 1-(2-Chloroethyl)Piperidinium Chloride
Chemical Family: Piperidinium compounds
Purity: ≥97% (as supplied for research)
Hazardous Components: 1-(2-Chloroethyl)Piperidinium Chloride (main), minor impurities possible
Impurities: Not specified, trace solvents or by-products from synthesis
Inhalation: Remove person to fresh air, keep at rest, seek immediate medical attention if symptoms persist such as respiratory distress, dizziness or drowsiness.
Skin Contact: Remove contaminated clothing rapidly, rinse skin with plenty of water for at least 15 minutes. Call a physician right away.
Eye Contact: Flush eyes with large amounts of water for at least 15 minutes, lifting eyelids, seek immediate medical help, show the chemical container or label.
Ingestion: Rinse mouth thoroughly if conscious, do not induce vomiting, never give anything by mouth if unconscious, get immediate medical attention.
Note to Physicians: Treat symptomatically. Consider effects on nervous and respiratory systems. Monitor for respiratory distress, seizures, or possible delayed symptoms.
Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam, water spray for large fires.
Unsuitable Extinguishing Media: Direct water stream on chemical can spread the fire.
Special Hazards: Emits toxic fumes of hydrogen chloride, nitrogen oxides, and carbon oxides under burning conditions.
Protective Equipment for Firefighters: Wear Department of Transportation (DOT) approved self-contained breathing apparatus, full protective turn-out gear.
Firefighting Advice: Remove containers from fire area if safe to do so. Prevent buildup of vapors. Keep upwind. Cool containers with water spray if exposed to fire. Maintain evacuation and isolation from affected area.
Explosion Data: No data for sensitivity to mechanical impact; avoid dust accumulation.
Personal Precautions: Evacuate unnecessary personnel, wear gloves, goggles, lab coat, NIOSH-approved respirator in poorly ventilated areas. Remove ignition sources.
Environmental Precautions: Prevent release to sewers, waterways, or soil. Notify proper authorities if contamination spreads.
Methods for Containment/Cleanup: Absorb with inert material (e.g. dry sand or earth, vermiculite), collect into chemical waste container for proper disposal. Avoid dust generation.
Decontamination: Wash spill site after material pickup is complete, ventilate the area. Dispose of cleaning materials as hazardous waste.
Safe Handling: Use fume hood if available. Avoid breathing dust, vapor, or mist. Prevent contact with skin, eyes, clothing. Do not eat, drink, or smoke when handling on lab bench.
Measures for Hygiene: Wash hands thoroughly after handling. Remove contaminated clothing and wash before reuse.
Storage Conditions: Store in tightly sealed container, in cool, dry, and well-ventilated place away from incompatible substances such as strong oxidizers and acids.
Storage Class: Toxic, hygroscopic chemicals.
Packaging Materials: Use non-reactive materials such as polyethylene or glass.
Specific Uses: Only permitted for laboratory or industrial use by trained professionals.
Engineering Controls: Work in properly functioning chemical fume hood. Provide eyewash stations and safety showers. Use non-sparking tools.
Respiratory Protection: Use NIOSH-approved respirators for toxic dusts/vapors if engineering controls fail.
Eye Protection: Chemical splash goggles or face shield.
Skin Protection: Impervious gloves (nitrile, neoprene), lab coat, chemical resistant apron.
Workplace Monitoring: Regularly monitor workplace air for hazardous concentrations.
Exposure Limits: No specific OSHA or ACGIH exposure limits set. Minimize exposure at all times.
Appearance: White or off-white crystalline powder
Odor: Slightly amine-like
Odor Threshold: Not available
pH: 3.5 - 5.5 (aqueous solution)
Melting Point/Freezing Point: 215–225°C (decomposes at range)
Boiling Point: Not applicable (decomposes)
Flash Point: Not determined
Evaporation Rate: Not determined
Flammability (solid): Not classified as flammable
Vapor Pressure: Negligible at ambient temperature
Vapor Density: Not determined
Relative Density: 1.2–1.3 (estimated)
Solubility: Soluble in water, slightly soluble in polar organic solvents
Partition Coefficient (n-octanol/water): Not determined
Auto-ignition Temperature: Not determined
Decomposition Temperature: Decomposes above 200°C, releases corrosive fumes
Viscosity: Not relevant (solid)
Chemical Stability: Stable under recommended storage conditions, sensitive to moisture
Conditions to Avoid: High humidity, heat, open flames, sources of ignition, prolonged light exposure
Incompatible Materials: Strong oxidizing agents, acids, alkalis, reactive metals
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, other toxic and corrosive fumes
Polymerization: Not expected to occur under normal handling but should be monitored in case of chemical contamination or excessive heat
Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin. LD50 (oral, rat): not available; structurally-related compounds show LD50 in range of 20–200 mg/kg
Skin Corrosion/Irritation: Causes irritation and possible burns
Serious Eye Damage/Irritation: Severe irritation, potential for permanent injury
Respiratory or Skin Sensitization: May cause allergic reactions, sensitization possible on repeated contact
Mutagenicity: Suspected based on structure and related chemicals; avoid exposure
Carcinogenicity: Not classified by ACGIH, IARC, OSHA, or NTP
Reproductive Toxicity: Insufficient data, avoid exposure in pregnancy
Repeated Dose Toxicity: Possible central nervous system and liver effects seen with related compounds
Symptoms: Burning of eyes and throat, cough, headache, nausea, muscular twitching, drowsiness, convulsions in severe cases
Ecotoxicity: Toxic to aquatic organisms, may cause long-term adverse effects in aquatic environments
Persistence and Degradability: Not readily biodegradable, persists in water/soil under some conditions
Bioaccumulation Potential: No specific studies, potential for accumulation in aquatic life
Mobility in Soil: Mobile in water, may leach to groundwater
Other Adverse Effects: Inhibition of microbial activity in soil and water possible at higher concentrations
Aquatic Toxicity Studies: Not available for this specific chemical; related alkylating agents show high toxicity to fish and invertebrates
Waste Disposal Methods: Dispose as hazardous waste via licensed chemical disposal contractor. Comply with local, regional, national, and international regulations. Do not discharge to drains.
Packaging Disposal: Treat empty containers as hazardous. Rinse thoroughly, puncture/leach, dispose in line with chemical waste protocols.
Incineration Recommendation: Chemical incineration in approved facility with afterburner and scrubber for halogenated waste
Precautions for Disposal: Do not mix with incompatible wastes; segregate for safety
Regulatory Constraints: U.S. EPA, Resource Conservation and Recovery Act (RCRA) classification may apply. Check permissible methods locally.
UN Number: 2811
UN Proper Shipping Name: Toxic solid, organic, n.o.s. (contains 1-(2-Chloroethyl)Piperidinium Chloride)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: II (medium danger)
Hazard Labels: Toxic
Environmental Hazards: Marine pollutant label recommended if transported in bulk
Special Precautions: Secure containers, follow shipment documentation, emergency response information must accompany transport
Other Requirements: Provisions of the International Air Transport Association (IATA), International Maritime Dangerous Goods (IMDG), and U.S. Department of Transportation (DOT) apply
U.S. Regulations: Listed as hazardous per OSHA Hazard Communication Standard. Not on SARA Title III section 313. Not on CERCLA or EPCRA lists.
TSCA Inventory: May require notification for new uses or import.
E.U. Regulations: Subject to Regulation (EC) No 1272/2008 (CLP). May be classed as toxic for use/release in European Union member countries.
Canadian Regulations: Controlled under WHMIS, classified as D1A (very toxic material).
Other National Regulations: Restrictions or reporting requirements exist in various countries.
Other Relevant Legislation: Follow employer’s health and safety plans, local permit and waste guidelines, and ensure proper worker training on handling dangerous chemicals.
