Product Name: 1,1'-Carbonylbis-1H-Imidazole
Synonyms: Carbonyldiimidazole, CDI, Carbonyl diimidazole
CAS Number: 530-62-1
Recommended Use: Reagent for peptide coupling, organic synthesis
Supplier: Refer to the chemical supplier’s internal documentation for emergency contact
Emergency Phone: Refer to company emergency contact or regional poison control
Classification: Skin irritation, Eye irritation, Acute toxicity oral and inhalation
Signal Word: Warning
Pictograms: Exclamation mark for irritant, health hazard
Hazard Statements: Causes skin irritation, Causes serious eye irritation, Harmful if inhaled, Harmful if swallowed
Precautionary Statements: Avoid breathing dust. Use only outdoors or in a well-ventilated area. Wash hands thoroughly after handling. Wear protective gloves/eye protection.
Chemical Name: 1,1'-Carbonylbis-1H-Imidazole
Chemical Formula: C7H6N4O
Molecular Weight: 162.15 g/mol
Ingredient Purity: ≥97%
Impurities: Minor organic contaminants below 1% based on batch analysis
CAS Number: 530-62-1
Inhalation: Move person to fresh air. Get medical attention if irritation or symptoms persist.
Skin Contact: Remove contaminated clothing. Wash skin thoroughly with soap and water. Seek medical attention if irritation develops.
Eye Contact: Rinse cautiously with water for at least fifteen minutes. Remove contact lenses if present. Get medical attention if irritation persists.
Ingestion: Do not induce vomiting. Rinse mouth thoroughly. Seek immediate medical care. Do not provide anything by mouth to an unconscious person.
Suitable Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or foam
Specific Hazards: Dust can form explosive mixtures with air. Hazardous gases such as nitrogen oxides and carbon monoxide may form during combustion.
Protective Equipment: Wear self-contained breathing apparatus and full protective gear.
Fire-Fighting Procedures: Move containers from fire area if possible without risk. Use water spray to cool unopened containers. Avoid inhaling combustion gases.
Personal Precautions: Evacuate unnecessary personnel. Avoid breathing dust and fumes. Ventilate area. Wear appropriate protective equipment (gloves, goggles, dust mask or respirator).
Environmental Precautions: Prevent entry to sewers and public waters. Collect spill using non-sparking tools.
Methods for Cleanup: Sweep up and place in a suitable, labeled, closed container for disposal. Clean spill area thoroughly with water and detergent.
Safe Handling: Work in a chemical fume hood, keep container tightly closed. Avoid dust formation. Wash hands after handling.
Storage Conditions: Store in a cool, dry, well-ventilated place. Protect from moisture. Keep container sealed and away from incompatible materials such as strong acids and bases, water, and oxidizing agents.
Incompatibilities: Moist air, strong oxidizers, strong acids and bases.
Occupational Exposure Limits: No established limits for this product. Use workplace exposure guidelines for dust.
Engineering Controls: Use local exhaust ventilation or closed systems to minimize dust. Provide eye wash and safety shower stations.
Personal Protective Equipment: Chemical splash goggles, gloves (nitrile or neoprene), lab coat, NIOSH-approved respirator if exposure risk present. Avoid contact with skin, eyes, and clothing.
Appearance: White to off-white crystalline powder
Odor: Faint, not distinctive
Odor Threshold: Data not available
pH: Slightly basic (in aqueous suspension)
Melting Point: 134 - 137°C
Boiling Point: Decomposes before boiling
Flash Point: Data not available
Flammability: Combustible dust
Vapor Pressure: Negligible at standard temperature
Solubility: Slightly soluble in water, soluble in organic solvents like DMSO and DMF
Partition Coefficient: Data not available
Decomposition Temperature: Data not available
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage conditions. Sensitive to moisture.
Reactivity: Reacts with water to generate carbon dioxide and imidazole.
Hazardous Reactions: Moisture exposure leads to hydrolysis and gas release.
Hazardous Decomposition Products: Imidazole, carbon dioxide, nitrogen oxides under fire or decomposition.
Incompatible Materials: Water, strong acids, strong bases, oxidizing agents.
Acute Toxicity: Harmful if swallowed, inhaled, or in contact with skin. Oral LD50 (rat) = 940 mg/kg
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Symptoms: Irritation to eyes, skin, respiratory tract; excessive dust inhalation may cause headache, dizziness
Chronic Effects: No available data on long-term effects
Carcinogenicity: Not listed by IARC, NTP, OSHA
Mutagenicity: No available data
Reproductive Toxicity: No available data
Ecotoxicity: Low acute toxicity expected for aquatic organisms, but no detailed long-term data
Persistence and Degradability: May hydrolyze slowly in moist soil or water to imidazole and carbon dioxide
Bioaccumulation: Not expected to bioaccumulate
Mobility in Soil: Low mobility expected due to low water solubility
Other Adverse Effects: No additional information available
Disposal Methods: Incinerate or dispose as hazardous waste according to local, regional, and national regulations. Do not release to environment.
Contaminated Packaging: Dispose in accordance with federal, state, and local regulations.
Disposal Precautions: Wear appropriate PPE, keep away from water and moisture during disposal.
UN Number: Not regulated for transport under most local guidelines
Transport Hazard Class: Not classified as a hazardous material under DOT, ADR, RID, IMDG, IATA
Packing Group: No assignment
Proper Shipping Name: Chemical, not otherwise specified
Environmental Hazards: Not classified as marine pollutant
Special Precautions: Protect from moisture during transport
TSCA Inventory Status: Listed
SARA Title III: Not subject to reporting
REACH Status: Registered or pre-registered
California Proposition 65: Not listed
WHMIS Classification: D2B (Toxic material causing other toxic effects)
Label Requirements: Comply with OSHA Hazard Communication Standard and local regulations
