People working in chemical procurement may not recognize the name, but the structure of 1-Boc-3-hydroxypyrrolidine stands out. The chemical comes with CAS 1092309-66-1 and features a pyrrolidine backbone with a Boc-protected hydroxy substituent on the third position. This compact molecule serves as a valuable building block in pharmaceutical synthesis and other fine chemistry fields. In China’s bustling fine chemical world, you find manufacturers and suppliers in direct competition to offer factory prices, which often brings better savings than going to European or North American sources. I've noticed companies advertising this compound as flakes or powder, with purity reaching as high as 99%. It often ships with a clear COA and up-to-date MSDS, crucial for buyers navigating strict regulatory environments. Factories in China with GMP certification supply both research-grade and commercial-bulk batches, fitting the demand for scale and certification like ISO, SGS, Halal, and Kosher standards. Looking at market data, bulk CIF and FOB rates have held steady over the last quarter, pointing to stable demand in APIs and specialty intermediates manufacturing.
Diving into the details, 1-Boc-3-hydroxypyrrolidine carries a molecular formula of C9H17NO3 and an HS Code frequently referenced as 2933990099. The material property data show a specific density around 1.13 g/cm³, often delivered as colorless to white flakes or solid powder. Each batch requires strict HPLC testing, and genuine suppliers readily provide the SDS, TDS, and reach-compliance documentation. Applications run across the board: from pharmaceutical intermediates to specialty raw materials in new drug research. From a procurement viewpoint, knowing every fact—molecular weight, formula, and even batch traceability—prevents headaches in downstream import inspections or customs clearance. The main Chinese suppliers offer samples and small MOQ orders before moving to bulk purchases, reducing risk in the market-entry phase. In my experience, professional buyers push for a sample, study particle consistency, and compare COA specs before locking down a large order.
China’s established chemical ecosystem allows direct sourcing from manufacturers holding both REACH registration and TDS availability. Quality certifications matter here; buyers serious about global supply routes should not only demand ISO and GMP but also halal and kosher for broader distribution, especially to markets in Southeast Asia and the Middle East. News and policy updates from Chinese exporters emphasize their compliance with environmental and workplace safety rules. On my last supplier search trip in Suzhou, I saw several factories allowing in-person inspection, which helps verify on-site production and warehousing. Experienced distributors provide quotes at both CIF and FOB terms, adapting to buyer needs on logistics and financing. Many suppliers even list real-time inventory status, a practical move for buyers needing consistent supply or caught in seasonal rush.
The bulk of demand comes from pharmaceutical, specialty chemical, and biotech firms. Market reports show a spike in requests for USP-grade intermediates, supported by large-scale Chinese factories with direct-to-customer shipping. The option to request free samples allows R&D teams to vet physical properties and reactivity in their own labs. This transparency increases buyer confidence before placing a minimum order quantity—often as low as 1 kg for inquirers. Regular supply updates, bulk pricing at both CIF and FOB, and full documentation all contribute to repeat orders. GMP-compliant facilities streamline purchase, simplify customs clearance, and support global expansion for smaller firms wanting to break into high-barrier regulated markets.
Handling 1-Boc-3-hydroxypyrrolidine demands respect for chemical safety. MSDS and SDS files supplied by factories detail every hazard, from inhalation to combustion risks. Bulk carriers and storage facilities meet modern fire and environmental standards, which often gets overlooked in fast-paced procurement. I always ask for REACH reports and a recent sample COA to make sure batch variability falls within narrow specs for density, melting point, and moisture level. The right supplier will send updated quality certifications, including ISO, Halal, and Kosher when requested. Keeping records straight supports not just everyday operations, but also audits by new business partners and regulators. Most competitive chemical suppliers from China adapt quickly to trends and provide fast response on quotes, bulk rates, and shipping dates—reducing downtime and keeping the production line running.
This intermediate finds a home in several applications. Pharmacy labs buy it for peptide synthesis and complex drug intermediates, with a strong pull from Asian, EU, and North American buyers. Inquiry and OEM requests have increased over the last year, with buyers asking for pine-solid pearls or liquid crystal forms, depending on the downstream product. Specific density, reactivity, and purity drive the purchase decision, as do price, sample support, flexible MOQ, and bulk inquiry policy. News feeds and supplier updates highlight increased market demand, especially with new pharmacological pipelines. Every reliable China-based factory posts not just price lists but also new certifications, REACH, ISO, SGS, and full application-use guidance so buyers make informed decisions. Those long email threads and late-night calls with suppliers pay off in smoother shipment, fewer regulatory headaches, and stronger supply chains, especially when the clock is ticking in drug R&D or specialty material production.
