D-Pyrrolidine-2-Carboxylic Acid, often referenced by its chemical formula C5H9NO2 or CAS number 5988-51-2, finds considerable use in pharmaceutical and biotech industries. Structurally, the molecule represents a cyclic amino acid, closely related to proline but existing in the D-configuration rather than the naturally abundant L-form. Looking at its appearance, the compound typically comes as flakes, solid powder, pearls, or sometimes even in a liquidcrystal display, giving suppliers flexibility in handling different end-use demands. Companies reference its HS-Code for customs declaration, and laboratories pay close attention to specifics like density, molecular weight (115.13 g/mol), and property stability under storage conditions for safe and consistent application. The crystalline form lasts under proper temperature and humidity, safeguarding quality for research or production batches.
Sourcing D-Pyrrolidine-2-Carboxylic Acid usually leads buyers to China, where a well-established network of supplier-manufacturer-factory relationships enables consistent availability and competitive pricing. Direct communication with manufacturers offers access to batch-specific MSDS, TDS, REACH, and SGS documentation, elements customers depend on for their own safety and compliance audits. Factories certified under GMP, ISO, and often halal or kosher standards signal reliability and adherence to strict processing guidelines. Many buyers, including those operating under OEM branding, scrutinize price per kilogram, bulk packaging options, and logistics plans under CIF or FOB Incoterms. Each quote often includes specific MOQ, but larger orders for the pharmaceutical sector typically secure more attractive wholesale rates. Free samples still play a part in the early evaluation stages, enabling R&D chemists to run pre-scale verifications before onboarding a new chemical raw material supplier.
Reputable Chinese suppliers list a detailed product specification catalogue for D-Pyrrolidine-2-Carboxylic Acid. The acid’s structure, with its pyrrolidine ring and attached carboxylate group, grants both reactivity and stability in a range of chemical reactions. A measured specific density, purity usually above 98%, and well-defined melting points give customers predictability in both synthesis and formulation. It comes as solid, flakes, or powder — granulation usually aligning with downstream requirements in pharmaceutical APIs or biocatalyst research. Many end-users care about the solvent compatibility, and manufacturers offer liter solution concentrations for process development or pilot runs. Hazard labeling based on GHS, safe handling guidelines, and chemical hazard codes appear on MSDS or SDS documents, reflecting real-life risks in handling or transport. Whenever customers request, manufacturers provide TDS sheets outlining storage temperatures, shelf-life, and recommended PPE for both the lab and the factory floor.
Pharmaceutical research drives the strongest demand, but D-Pyrrolidine-2-Carboxylic Acid also shows up in fine chemical synthesis, peptide design, and sometimes agricultural R&D. It acts as a chiral building block in the synthesis of drug molecules and advanced intermediates, powering growth in CDMO and contract manufacturing partnerships. Market reports for 2024 point to rising global demand for high-purity amino acid derivatives, a reflection of biosimilar and generics expansion worldwide. Import regulations have grown tighter, so compliance with REACH, ISO, and TDS standards isn’t just preferable, it’s a baseline. Price competition stays fierce, especially between major Chinese suppliers and smaller specialty factories that may offer niche formulations or custom synthesis on request. Distributors help with MOQ negotiations for those unable to commit to full-container-load purchases. Inquiries often arrive seeking both bulk CIF prices and small “for sale” sample lots, feeding into a broader trend of simultaneous large-scale production and small-scale investigation.
Handling D-Pyrrolidine-2-Carboxylic Acid does not come without hazards. MSDS sheets from trusted suppliers spell out eye, skin, and inhalation risks, listing appropriate chemical spill procedures, waste disposal, and recommended storage containers. Chinese factories observing GMP and ISO frameworks implement robust training for workers and enforce strict environmental controls, responding to growing scrutiny from both Chinese and international regulators. Halal and kosher certification holds weight in global markets, opening doors beyond traditional pharma buyers, and bringing additional export value. Quarterly audits ensure compliance, and SGS certification acts as a third-party seal of trust for customers with demanding supply chain risk policies. As more multinationals seek China-based suppliers for cost efficiency, real-world safety, environmental management, and honest certification reporting move from marketing bullet points to crucial dealbreakers.
I have spoken with procurement managers in both pharmaceutical and flavor industries, and many stress the importance of transparency from chemical suppliers. It’s rare now for buyers to choose a partner based on price alone; instead, up-to-date safety documentation, quick access to sample shipments, and proven supply consistency earn long-term business. Market data shows rising competition in China spurs not only lower costs but also improvement in quality management and material traceability. Industry forums and news reports draw attention to policy changes — such as stricter export controls and stronger enforcement of REACH-style regulations — signaling a shift toward improved safety and sustainability for exported raw materials and intermediates. Applications keep growing as peptide synthesis and green chemistry accelerate. Buyers searching for D-Pyrrolidine-2-Carboxylic Acid now look to trusted Chinese factories for scalable, certified, and safe solutions, comparing supplier-specific MOQs, bulk rates, REACH status, and OEM flexibility with a keen eye for long-term partnership.
